Title: The Best 5 Star Hotels in Mestre from $99 | Expedia.com [Mestre Travel Guide](https://expedia.com/Mestre.dx4952)[Hotels in Mestre](https://expedia.com/Mestre-Hotels.d4952.Travel-Guide-Hotels)[Vacation Rentals in Mestre](https://expedia.com/Mestre-Vacation-Rentals.d4952.Travel-Guide-VacationRentals)[Flights to Mestre](https://expedia.com/Cheap-Flights-To-Mestre.d4952.Travel-Guide-Flights)[Things to do in Mestre](https://expedia.com/Things-To-Do-In-Mestre.d4952.Travel-Guide-Activities)[Car Rentals in Mestre](https://expedia.com/Car-Rentals-In-Mestre.d4952.Car-Rental-Guide)[Mestre Vacation Packages](https://expedia.com/Mestre.d4952.Destination-Travel-Guides) ![Aerial view of Forte Marghera in Mestre Italy former Austrian fortification protecting Venice with water filled moat, artillery bastion, barracks](https://images.trvl-media.com/place/3000661740/a83a86a7-cba6-4aa9-b16a-464a88306f2c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/3000661740/a83a86a7-cba6-4aa9-b16a-464a88306f2c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check availability on Mestre 5 Star Hotels Tonight [Mar 13 - Mar 14](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-03-13&endDate=2026-03-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 14 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-03-14&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=4952&startDate=2026-03-20&endDate=2026-03-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mestre 5-star hotels ![3 restaurants, breakfast, lunch, dinner served; Italian cuisine](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/3906e85f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite | Living area | 40-inch LED TV with satellite channels, TV, toys](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/437518fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/w2835h1889x0y1-c089b1f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1590000/1583200/1583191/ab9c1295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Molino Stucky Venice [](https://www.expedia.com/Venice-Hotels-Hilton-Molino-Stucky-Venice.h1583191.Hotel-Information) La Giudecca 8.8/10 Excellent (1,002 reviews) "Nice hotel with lots of amenities" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) cem $214 nightly $246 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Hilton-Molino-Stucky-Venice.h1583191.Hotel-Information) ![2 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/dd59d66c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/090ab099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/ed3577a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Roof Garden Suite | 1 bedroom, Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/10000/3700/3624/9a48eacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The St. Regis Venice [](https://www.expedia.com/Venice-Hotels-The-St-Regis-Venice.h3624.Hotel-Information) Venice City Center 9.6/10 Exceptional (120 reviews) "The hotel is amazing, placed in the heart of Venice and every single person from the staff was incredible to me and my family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nicolás $1,178 nightly $1,307 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-The-St-Regis-Venice.h3624.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/2a7b0bd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/91ca31d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/499585a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/210000/201300/201235/e0e40e82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Venezia Grand Hotel Dei Dogi [](https://www.expedia.com/Venice-Hotels-NH-Collection-Venezia-Grand-Hotel-Dei-Dogi.h201235.Hotel-Information) Cannaregio 9.0/10 Wonderful (489 reviews) "We had a wonderful time, and the receptionist gave us a fabulous restaurant recommendation close by. Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Francisco $296 nightly $337 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-NH-Collection-Venezia-Grand-Hotel-Dei-Dogi.h201235.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/c87a4de0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/d92edb1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/5d244e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/450000/445200/445128/37bd28ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baglioni Hotel Luna - The Leading Hotels of the World [](https://www.expedia.com/Venice-Hotels-Baglioni-Hotel-Luna-The-Leading-Hotels-Of-The-World.h445128.Hotel-Information) Venice City Center 9.4/10 Exceptional (1,000 reviews) "Perfect location, superb service, immaculate rooms, fabulous breakfast, top notch bar and bar staff. It's ideal in every way." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Guy $660 nightly $737 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Baglioni-Hotel-Luna-The-Leading-Hotels-Of-The-World.h445128.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/4cf86529.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/3ad3eb1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/f30d6942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Canal | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/93000000/92020000/92013900/92013875/e987c616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Venice Venice Hotel [](https://www.expedia.com/Venice-Hotels-The-Venice-Venice-Hotel.h92013875.Hotel-Information) Venice City Center 9.8/10 Exceptional (105 reviews) "Excellent location staff restaurant and hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Noof $765 nightly $854 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-The-Venice-Venice-Hotel.h92013875.Hotel-Information) ![Daily buffet breakfast (EUR 36 per person)](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/719475d8_edited_be99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/91ea3e91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/e078e07d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/65000000/64670000/64665900/64665805/c237d8a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Collection Hotel, Palazzo Nani Venice [](https://www.expedia.com/Venice-Hotels-Radisson-Collection-Palazzo-Nani.h64665805.Hotel-Information) Cannaregio 9.8/10 Exceptional (177 reviews) "Nice staff, nice room, location is ok." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Priscilla $354 nightly $401 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Radisson-Collection-Palazzo-Nani.h64665805.Hotel-Information) ![Lounge](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/a22a5078.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom | Frette Italian sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/55c0f55d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Pool](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/1d6be914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 Bedroom | Frette Italian sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/27300/27226/8f782ea8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Gritti Palace, a Luxury Collection Hotel, Venice [](https://www.expedia.com/Venice-Hotels-The-Gritti-Palace.h27226.Hotel-Information) Venice City Center 9.4/10 Exceptional (241 reviews) "Excellent place " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Prabakar $1,838 nightly $2,033 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-The-Gritti-Palace.h27226.Hotel-Information) ![Staircase](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/1e825745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/854b47f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/2b709ed2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/0fa00b29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ca' Sagredo [](https://www.expedia.com/Venice-Hotels-Ca-Sagredo.h1593284.Hotel-Information) Venice City Center 9.2/10 Wonderful (481 reviews) "Beautiful clean room, very helpful staff. Strongly recommended." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hakima $322 nightly $366 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Ca-Sagredo.h1593284.Hotel-Information) ![Suite, City View (terrace) | Living area | 32-inch Smart TV with satellite channels](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/d9ccabd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; local cuisine, alfresco dining ](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/f1f44d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/w4835h3305x0y0-251e16dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/16000000/15130000/15124400/15124381/eb0fed40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Venart Luxury Hotel [](https://www.expedia.com/Venice-Hotels-Palazzo-Venart-Luxury-Hotel.h15124381.Hotel-Information) Venice City Center 9.8/10 Exceptional (169 reviews) "Beautiful apartment with all the amenities one would need. Also, a quieter part of Venice but close enough to restaurants and shopping " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher $693 nightly $773 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Palazzo-Venart-Luxury-Hotel.h15124381.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/818dbb2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/03d8dcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Pool Access, City View | City view](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/99823920.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Grand Master Suite | Premium bedding, Tempur-Pedic beds, free minibar items, in-room safe](https://images.trvl-media.com/lodging/77000000/76980000/76973400/76973344/dcb9e55c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nolinski Venezia - Evok Collection [](https://www.expedia.com/Venice-Hotels-Nolinski-Venezia.h76973344.Hotel-Information) Venice City Center 9.8/10 Exceptional (107 reviews) "Beautiful hotel, great location, and amazing staff. This is my new favorite hotel in Venice! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dee $858 nightly $955 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Nolinski-Venezia.h76973344.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/3707a5e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/8a0ef0a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, Canal View (Grand) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/w4287h2850x3y0-6a277d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2060000/2051500/2051446/257d57e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sina Centurion Palace [](https://www.expedia.com/Venice-Hotels-Sina-Centurion-Palace.h2051446.Hotel-Information) Dorsoduro 9.0/10 Wonderful (619 reviews) "Everything was wonderful....great staff..all with loads of personality....best stay i have ever had in multiple trips to Venice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Garry $340 nightly $386 total Mar 30 - Mar 31 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Sina-Centurion-Palace.h2051446.Hotel-Information) ![55-inch flat-screen TV with satellite channels, TV, Netflix](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/4208a326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/f19871a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/1c50292f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Rio Moise) | Premium bedding, down comforters, memory foam beds, free minibar items](https://images.trvl-media.com/lodging/1000000/980000/971000/970957/e8a75159.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Violino D’Oro Venezia [](https://www.expedia.com/Venice-Hotels-Violino-DOro-Venezia.h970957.Hotel-Information) Venice City Center 10/10 Exceptional (57 reviews) "Great location, staff, and breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) D $733 nightly $818 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Violino-DOro-Venezia.h970957.Hotel-Information) ![Presidential Suite, Canal View | Premium bedding, minibar, in-room safe, soundproofing](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/53ae629f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/9c328f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/5604508d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20210000/20204900/20204896/c430443c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Nani Mocenigo Palace [](https://www.expedia.com/Venice-Hotels-Hotel-Nani-Mocenigo-Palace.h20204896.Hotel-Information) Dorsoduro 9.8/10 Exceptional (683 reviews) "The staff was so very accommodating, making us feel very special. The rooms were spotless and the bedding lovely. The shower was amazing! Delicious food in the restaurant both for breakfast and dinner. The location was convenient and yet quiet away from tourist areas. We would highly recommend this hotel again and again . Lastly, when you go back to the airport please consider the private water taxi. It was fun, gorgeous and efficient. Definitely worth the price and the hotel made all... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tori $332 nightly $377 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Hotel-Nani-Mocenigo-Palace.h20204896.Hotel-Information) ![In-room dining](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/7efcda71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite Supreme, Canal View | Living area | 60-inch Smart TV with satellite channels, TV](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/86a68dd1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/2a4588c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Minibar, in-room safe, desk, soundproofing](https://images.trvl-media.com/lodging/23000000/22840000/22836800/22836766/364311b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cà Bonfadini Historic Experience [](https://www.expedia.com/Venice-Hotels-Ca-Bonfadini-Historic-Experience.h22836766.Hotel-Information) Cannaregio 9.8/10 Exceptional (212 reviews) "Beautiful hotel - great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neetu $351 nightly $397 total Mar 17 - Mar 18 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Ca-Bonfadini-Historic-Experience.h22836766.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/4c71c1a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/db44ede8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Studio Suite, Canal View | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/9af6cbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Turkish bath](https://images.trvl-media.com/lodging/2000000/1710000/1703300/1703221/7795bc74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### EXCESS VENICE Boutique Hotel & Private Spa - Adults Only [](https://www.expedia.com/Venice-Hotels-EXCESS-VENICE-Boutique-Hotel-Private-Spa.h1703221.Hotel-Information) Dorsoduro 9.4/10 Exceptional (156 reviews) "Very nice place to stay very clean and very kind and helpful staff 100% recommend this place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ryan $157 nightly $184 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-EXCESS-VENICE-Boutique-Hotel-Private-Spa.h1703221.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/1c5f14c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite (Grand Canal) | Down comforters, minibar, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/w8589h5723x0y3-810bd8e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite (Grand Canal) | View from room](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/2a43c3ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1500000/1498000/1497971/c8003260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzina Grassi [](https://www.expedia.com/Venice-Hotels-Palazzina-Grassi.h1497971.Hotel-Information) Venice City Center 9.2/10 Wonderful (222 reviews) "Everyone was very friendly & excellent service! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patrick $573 nightly $642 total Mar 16 - Mar 17 Total with taxes and fees [](https://www.expedia.com/Venice-Hotels-Palazzina-Grassi.h1497971.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/5330e15c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Canal View | View from room](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/8cc7fb6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/b2ddfbd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Canal View | Down comforters, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/92000000/91550000/91542200/91542192/07ab6aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Eight Venezia [](https://www.expedia.com/Venice-Hotels-Palazzo-Maria-Formosa.h91542192.Hotel-Information) Castello 9.8/10 Exceptional (60 reviews) "Beautiful hotel and staff amazing. Loved our stay " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Simon John [](https://www.expedia.com/Venice-Hotels-Palazzo-Maria-Formosa.h91542192.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/bf1d57bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/8504ad64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/cdb2c47f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2940000/2938800/2938724/95feb0e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bauer Casa Nova [](https://www.expedia.com/Venice-Hotels-Bauer-Casa-Nova.h2938724.Hotel-Information) Venice City Center [](https://www.expedia.com/Venice-Hotels-Bauer-Casa-Nova.h2938724.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mestre-Hotels.s50-0-d4952.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Mestre-Hotels.s50-0-d4952.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mestre. ![Amadeus Hotel](https://images.trvl-media.com/lodging/1000000/10000/7400/7339/ef042085_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Amadeus Hotel Lista di Spagna Venice VE $81 nightly $99 total Mar 24 - Mar 25 Total with taxes and fees 8/10 Very Good! (1,001 reviews) [](https://expedia.com/Venice-Hotels-Amadeus-Hotel.h7339.Hotel-Information) ![Hotel Principe](https://images.trvl-media.com/lodging/1000000/20000/11400/11393/f4fecbd5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Principe Rio Tera Lista de Spagna, 146 Venice VE $88 nightly $108 total Mar 24 - Mar 25 Total with taxes and fees 8.8/10 Excellent! (1,001 reviews) [](https://expedia.com/Venice-Hotels-Hotel-Principe.h11393.Hotel-Information) ![Hotel Cavalletto e Doge Orseolo](https://images.trvl-media.com/lodging/1000000/10000/3600/3575/f038f496_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Cavalletto e Doge Orseolo Piazza San Marco 1107 Venice VE $124 nightly $146 total Mar 18 - Mar 19 Total with taxes and fees 8.8/10 Excellent! (1,708 reviews) [](https://expedia.com/Venice-Hotels-Hotel-Cavalletto-E-Doge-Orseolo.h3575.Hotel-Information) Still don't see what you're looking for? [See all properties in Mestre.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=4952&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=4952&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=4952&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=4952&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=4952&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F14%2F2026&endDate=3%2F15%2F2026®ionId=4952&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Mestre While often overlooked as Venice's mainland gateway, Mestre offers its own treasures with the striking Torre Civica and vibrant Piazza Ferretto at its heart. Catch performances at Teatro Toniolo or rent bikes to explore Parco San Giuliano's green spaces with spectacular views across the lagoon. [See all hotels in Mestre](https://www.expedia.com/Hotel-Search?startDate=2026-03-27&endDate=2026-03-28&adults=2®ionId=4952) ![Aerial view of Forte Marghera in Mestre Italy former Austrian fortification protecting Venice with water filled moat, artillery bastion, barracks](https://images.trvl-media.com/place/3000661740/a83a86a7-cba6-4aa9-b16a-464a88306f2c.jpg?impolicy=fcrop&w=900&h=362&p=1&q=high) ## Top Mestre Hotel Reviews ## Find out more about Mestre You enjoy the finer things in life, both at home and on vacation. Why not demand total luxury on your trip to Mestre? There's no reason to delay a getaway to Mestre any longer. You'll join the multitudes of vacationers who have made Mestre so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. What are you waiting for? Book one of Expedia's luxurious 5-star hotels in Mestre and get ready to be pampered like never before. ### 5-Star Hotels in Mestre You'll have a fantastic time at one of these 5-star hotels. Highly-rated eateries, top-notch customer care, and fabulous spa offerings are waiting for you. We've got 79 hotels in Mestre, some of which will have exactly what you desire. You can also look forward to an outstanding experience and fantastic customer care, so get ready for a wonderful adventure. How do you want to relax? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A mud wrap treatment that will leave you feeling refreshed and alive? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs. You won't sleep and order room service the entire time, though. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. Whatever you plan to do, the 5-star hotels in Mestre are the perfect place to relax after a busy day. ### Make Your Escape Numerous visitors make Mestre the place to vacation. Why not join their ranks? If you've been dreaming about a vacation set here, then go ahead and book it. A surge in interest means these great hotel rooms will go quickly. It's time to indulge yourself. Select one of our Mestre 5-star hotels today and settle down in complete comfort tomorrow. ## Frequently asked questions ### What are the best 5-star hotels in Mestre? ### How much does it cost to stay in a 5-star hotel in Mestre? > - Search for the lowest price per night from $99 ### What makes a hotel 5 stars in Mestre? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hotels near Ferretto Square ](https://www.expedia.com/Ferretto-Square-Hotels.0-l6163963-0.Travel-Guide-Filter-Hotels) - [Hotels near Municipal Tower of Mestre ](https://www.expedia.com/Municipal-Tower-Of-Mestre-Hotels.0-l6224447-0.Travel-Guide-Filter-Hotels) - [Hotels near Toniolo Theatre ](https://www.expedia.com/Toniolo-Theatre-Hotels.0-l6222778-0.Travel-Guide-Filter-Hotels) - [Hotels near Mestre City Center ](https://www.expedia.com/Mestre-City-Center-Venice-Hotels.0-n3000661743-0.Travel-Guide-Filter-Hotels) - [Casino Hotels in Mestre City Center ](https://www.expedia.com/Mestre-City-Center-Venice-Hotels-Casino-Hotel.0-n3000661743-0-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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