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Featured Panama 5 Star Hotels

See all 494 Hotels in Panama
Trump International Hotel and Tower Panama

Trump International Hotel and Tower Panama

Calle Punta Colon, Punta Pacifica, Panama City
5.0 out of 5.0
4.3 out of 5 (407 reviews)
Amazing Experience !Everything was first class ! From check in, customer service, the restaurants and all. Thanks Trump Hotels and Expedia !
  Sep 25, 2017

$149

$149
Bristol Panama

Bristol Panama

Avenida Aquilino de La Guardia, Panama City
5.0 out of 5.0
4.6 out of 5 (167 reviews)
Great hotel in the cityThe experience here was great! The staff was very friendly. They navigated me through things in the city. The spa was excellent and the food was good too. Check out there breakfast and make sure you go to the spa
  Sep 25, 2017

$127

$127
Waldorf Astoria Panama

Waldorf Astoria Panama

47th St. & Uruguay Street, Panama City
5.0 out of 5.0
4.4 out of 5 (152 reviews)
Surprising location for WAOverall, a good hotel, but not the Waldorf Astoria experience you would expect. The hotel is in an odd location although near all the skyscrapers. The room was ok, but the wallpaper in the bathroom was coming off and patched badly in two sections. the hotel restaurant Brio was terrible and extremely ...
  Aug 17, 2017

$135

$135
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

Km 6 Road to Veracruz, Panama City
5.0 out of 5.0
4.2 out of 5 (133 reviews)
Great staff. Impressive looking. So-so cleanlinessThe hotel staff was amazing and welcoming to me and my family. Overall the resort is impressive and hanging by the pool was a treat. Very comfy bed and absolutely stunning view. Don't take a taxi from the hotel as a non-resident. $25-$30 to go into the city when locals only pay $4-$6. Definitely ...
  Sep 4, 2017

$173

$173
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There's nothing wrong with enjoying the finer things in life. Add an extra layer of luxury on your next trip to Panama by treating yourself to the best of the best when it comes to lodging. It's an ideal fusion. After all, this is one of the Top 100 locations in Expedia's portfolio! You'll join the multitudes of vacationers who have made Panama so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve the great vacation you're dreaming about. Our 5-star hotels in Panama are the perfect places to relax in during your next escape.

5-Star Hotels in Panama

You'll have a fantastic time at one of these 5-star hotels. Excellent service, delicious meals, and personalized service are all waiting for you. Our numerous hotels in the area will ensure you find the perfect space to kick back after a long day. You'll also enjoy a high standard of care and meticulous guest relations, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? A concierge to help you suggest the next attraction to visit? A deep-tissue massage to help your cares fall away? Comfortable beds, lip-smacking main courses, and even spectacular views...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs.

But you aren't going to spend your entire vacation in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Panama are the perfect place to rest up after a busy day.

Make Your Escape

The results are in, and Panama 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- this is a great time to find 5-star hotel deals in @region! Select one of our Panama 5-star hotels today and soothe yourself in luxe surroundings tomorrow.

Recently booked 5 Star Hotels in Panama

Waldorf Astoria Panama
5.0 out of 5.0
Last booking: 2 hours ago