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Featured San Francisco 5 Star Hotels

See all 521 Hotels in San Francisco
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,035 reviews)
Nice hotel downtownStayed here after a holiday party, linens etc were nice, hotel very nicely maintained, but rooms didnt have a ton of character
  Dec 17, 2017

$167

$167
Omni San Francisco Hotel

Omni San Francisco Hotel

500 California St, San Francisco
5.0 out of 5.0
4.7 out of 5 (3,333 reviews)
In the center of the financial district Very nice welcoming staff. Room was quiet, pleasant and roomy. Like the holiday candy display of large gingerbread buildings in the lobby.
  Dec 16, 2017

$166

$166
Argonaut Hotel - a Noble House Hotel

Argonaut Hotel - a Noble House Hotel

495 Jefferson St, San Francisco
5.0 out of 5.0
4.6 out of 5 (5,623 reviews)
Amazing location, nice staff, interesting nautical theme but not excessive.
  Dec 11, 2017

$142

$142
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
5.0 out of 5.0
4.6 out of 5 (1,540 reviews)
Fantastic Staff and a Beautiful HotelThe location on Nob Hill is perfect. Every aspect of my stay was delightful. The staff is professional, accommodating and friendly.
  Dec 16, 2017

$212

$212
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
5.0 out of 5.0
4.5 out of 5 (2,864 reviews)
Very clean and nice hotel with a friendly staff.
  Dec 17, 2017

$143

$143
Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco
5.0 out of 5.0
4.7 out of 5 (378 reviews)
Great Hotel with a Great ViewLoved the breakfast. Really clean rooms and great service!
  Dec 15, 2017

$239

$239
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (773 reviews)
Great location central to most SF landmarksGreat location and very nice room. The staff was exceptionally friendly and well trained. The location is ideal, near many SF points of interest. I highly recommend this hotel if price is not an issue.
  Dec 12, 2017

$369

$369
The St. Regis San Francisco

The St. Regis San Francisco

125 3rd St, San Francisco
5.0 out of 5.0
4.7 out of 5 (304 reviews)
Beautiful hotelWonderful hotel. Elegant! Great staff. Our breakfast was delicious
  Dec 15, 2017

$336

$336
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

757 Market St, San Francisco
5.0 out of 5.0
4.5 out of 5 (478 reviews)
Position is great in San Francisco! In the evening the hotel and the bar is a little bit to crowded but it’s ok.
  Dec 15, 2017

$395

$395
Taj Campton Place

Taj Campton Place

340 Stockton St, San Francisco
5.0 out of 5.0
4.6 out of 5 (908 reviews)
Friendly staff, great location. Were forthcoming about an upgrade and proactively offered us late checkout. Will stay again!
  Dec 16, 2017

$270

$270
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Treat your every desire on your upcoming break. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made San Francisco so popular in the last year. Come see what all the excitement is about. We should also mention, the hotels in this area are known for guest services, so you know you'll be well cared for during your getaway. Reserve one of our 5-star hotels in San Francisco and indulge in the finer things in life for a while. What are you waiting for?

Get a Great Deal on 5-Star Hotels in San Francisco

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Highly-rated eateries, exceptional customer care, and fabulous spa offerings are waiting for you. We have a huge number of hotels in the region, and all of them offer awesome amenities. Additionally, the hotels in this area receive fantastic marks for guest services, so you know you'll be looked after during your getaway. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling refreshed and alive? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A Swedish massage to help your cares fall away? Want to see for yourself? Then explore the 13,157 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? You're in luck. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals -- they'll be happy to sit down for a pint or a cuppa.

Your Getaway Starts Today

The results are in, and San Francisco 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Your great getaway is just a mouse-click away -- this is a great time to find 5-star hotel deals in @region! Choose one of Expedia's San Francisco 5-star hotels today and soothe yourself in complete comfort tomorrow.

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