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Featured San Francisco 5 Star Hotels

See all 525 Hotels in San Francisco
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,029 reviews)
Comfortable hotelI love staying at the Palace Hotel. The beds and pillows are so comfortable and the rooms are spacious and clean. The staff are very helpful and the location of the hotel is very central.
  Dec 6, 2017

$167

$167
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,842 reviews)
Great hotel in beautiful San Francisco. Only downside is that you have to walk up a big hill!
  Dec 8, 2017

$199

$199
Omni San Francisco Hotel

Omni San Francisco Hotel

500 California St, San Francisco
5.0 out of 5.0
4.7 out of 5 (3,332 reviews)
2nd stay in a week!We enjoyed our overnight stay at the Omni the previous week that when we came across a great price, we jumped at a little 'staycation' in the city to enjoy the lights with our children. After a wonderful walk, we came back to cookies and milk - kids were over the moon! Friendly staff; hot cider was ...
  Dec 11, 2017

$166

$166
Argonaut Hotel - a Noble House Hotel

Argonaut Hotel - a Noble House Hotel

495 Jefferson St, San Francisco
5.0 out of 5.0
4.6 out of 5 (5,620 reviews)
Amazing location, nice staff, interesting nautical theme but not excessive.
  Dec 11, 2017

$142

$142
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
5.0 out of 5.0
4.6 out of 5 (1,541 reviews)
Excellent hotelNice Hotel, excellent locations and nice staff. Will stay here in my next trip to SF for sure.
  Dec 8, 2017

$212

$212
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
5.0 out of 5.0
4.5 out of 5 (2,858 reviews)
Always stay at Intercontinental and have never been disappointed. Rooms are quiet, restaurant is wonderful, beds comfortable... not much else to say!
  Dec 4, 2017

$143

$143
Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco
5.0 out of 5.0
4.7 out of 5 (377 reviews)
Always a great place to stay! Plenty of things to do within this hotel and outside of it!
  Dec 8, 2017

$239

$239
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (770 reviews)
Amazing serviceThe hotel was a perfect blend of contemporary and classic. The staff were incredible, attentive, and friendly. They really made it feel like home away from home. Can’t wait for my next stay!
  Nov 16, 2017

$369

$369
The St. Regis San Francisco

The St. Regis San Francisco

125 3rd St, San Francisco
5.0 out of 5.0
4.7 out of 5 (302 reviews)
great locationSF is a walking town and this hotel is in a great location. Staff uniformly warm, welcoming, knowledgeable, helpful and efficient. Room was comfortable and quiet.
  Nov 30, 2017

$336

$336
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

757 Market St, San Francisco
5.0 out of 5.0
4.5 out of 5 (474 reviews)
Awesome hotelThis hotel has to be one of my favorites! This was the second time that I stayed here and it never seems to fail! The staff is great, room is awesome and the view is one of a kind! Will be coming back next year!
  Nov 27, 2017

$395

$395
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Treat your every desire on your upcoming break. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made San Francisco so popular in the last year. Come see what all the excitement is about. We should also mention, the hotels in this area are known for guest services, so you know you'll be well cared for during your getaway. Reserve one of our 5-star hotels in San Francisco and indulge in the finer things in life for a while. What are you waiting for?

Get a Great Deal on 5-Star Hotels in San Francisco

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Highly-rated eateries, exceptional customer care, and fabulous spa offerings are waiting for you. We have a huge number of hotels in the region, and all of them offer awesome amenities. Additionally, the hotels in this area receive fantastic marks for guest services, so you know you'll be looked after during your getaway. What kind of amenities will make your stay a wonderful one? A mud wrap treatment that will leave you feeling refreshed and alive? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A Swedish massage to help your cares fall away? Want to see for yourself? Then explore the 13,157 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? You're in luck. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals -- they'll be happy to sit down for a pint or a cuppa.

Your Getaway Starts Today

The results are in, and San Francisco 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Your great getaway is just a mouse-click away -- this is a great time to find 5-star hotel deals in @region! Choose one of Expedia's San Francisco 5-star hotels today and soothe yourself in complete comfort tomorrow.

Recently booked 5 Star Hotels in San Francisco

Fairmont San Francisco
5.0 out of 5.0
Last booking: 25 minutes ago
Palace Hotel, a Luxury Collection Hotel, San Francisco
5.0 out of 5.0
Last booking: 1 hour ago