Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search over 1,000,000 properties worldwide and 550 airlines worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Santorini

Best deal Aug 16 - Aug 18
Tonight Jun 20 - Jun 21
This weekend Jun 21 - Jun 23
Next weekend Jun 28 - Jun 30

Featured Santorini 5 Star Hotels

See all 1,369 Properties in Santorini

Estimated price for 1 night/2 adults

De Sol Spa Hotel
De Sol Spa Hotel
5.0 out of 5.0 Fira, Santorini, Santorini Island
4.5/5 (170 reviews)
$151/ night for 2 guests

Serene, beautiful surroundings and amazing service.

Reviewed on May 5, 2019
Andronis Arcadia Hotel
Andronis Arcadia Hotel
5.0 out of 5.0 Oia, Santorini, Santorini Island
5.0/5 (3 reviews)
$1,154/ night for 2 guests
Aqua Blue Hotel
Aqua Blue Hotel
5.0 out of 5.0 Perissa, P.O. Box 121, Santorini, Cyclades
4.8/5 (115 reviews)
$217/ night for 2 guests

Beautiful room and excellent staff. Great respite from the over tourism of Fira.

Reviewed on Jun 11, 2019
Volcano View Hotel & Villas
Volcano View Hotel & Villas
5.0 out of 5.0 Fira, Santorini, Santorini Island
4.6/5 (442 reviews)
$193/ night for 2 guests

This is heaven! Beautiful staff, property views, pool and room. The bus from the ferry stopped in front of the hotel. The hotel also offers free shuttle to downtown Fira bus station so you will not need a car. I have to give a big thank you to Sophia who worked at the pool for being so kind and teaching ...

Reviewed on Jun 4, 2019
Santorini Princess Luxury Spa Hotel
Santorini Princess Luxury Spa Hotel
5.0 out of 5.0 Imerovigli, Santorini, Santorini Island
4.9/5 (570 reviews)
$269/ night for 2 guests

Everything was as described. We loved our stay, our room was lovely with spectacular view. The location was perfect for us as it was quiet compare to Oia but occasionally there was a loud music playing in nearby bar which was very disturbing when you try to relax by the pool. We would not rather ...

Reviewed on Jun 15, 2019
Santo Maris Oia, Luxury Suites & Spa
Santo Maris Oia, Luxury Suites & Spa
5.0 out of 5.0 Oia, Santorini
4.8/5 (147 reviews)
$560/ night for 2 guests

amazing place, great location, great staff, a wonderful stay

Reviewed on Jun 18, 2019
Katikies Hotel
Katikies Hotel
5.0 out of 5.0 Oia, Santorini, Santorini Island
4.8/5 (186 reviews)
$1,082/ night for 2 guests

Everything was beautiful and the entire staff was extremely attentive. Wonderful stay!

Reviewed on Jun 15, 2019
Lilium Villas
Lilium Villas
5.0 out of 5.0 Fira Town, Santorini, Santorini Island
4.8/5 (437 reviews)
$311/ night for 2 guests

Excellent hoyel best in town Location perfect Facilities top view the best

Reviewed on May 31, 2019
Pegasus Suites & Spa
Pegasus Suites & Spa
5.0 out of 5.0 Imerovigli, Santorini, Santorini Island
4.5/5 (100 reviews)
$391/ night for 2 guests

Loved the location, staff, and property. Only disliked the fruit fly problem

Reviewed on May 26, 2019
Map

Indulge your every desire on your impending sabbatical. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Santorini so popular in the last year. As you might have known, this is one of the Top 100 locations in Expedia's portfolio! You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Our 5-star hotels in Santorini are the perfect places to relax in when you really need to escape. You deserve the great vacation you're dreaming about.

Book the Best Santorini 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. Michelin-starred restaurants, exceptional customer care, and rejuvenating spa offerings are waiting for you. We have a huge number of hotels in the area, and all of them offer outstanding amenities. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? A full-body massage to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? Plush carpeting, lip-smacking main courses, and even a hot tub in the bathroom...these hotels will leave you amazed.

But you aren't going to spend your entire vacation in your room, of course. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Santorini are the perfect place to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Santorini 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- this is a great time to find 5-star hotel deals in @region! Select one of Expedia's Santorini 5-star hotels today and relax in the lap of luxury at your convenience.

Recently booked 5 Star Hotels in Santorini

Splendour Resort
4.0 out of 5.0
Last booking: 1 hour ago
Smaragdi Hotel
3.0 out of 5.0
Last booking: 2 hours ago
Sea of Aegeon
3.0 out of 5.0
Last booking: 2 hours ago
Aigialos Luxury Traditional Settlement
5.0 out of 5.0
Last booking: 4 hours ago
San Giorgio
2.0 out of 5.0
Last booking: 4 hours ago
Maistros Village
4.5 out of 5.0
Last booking: 4 hours ago
Antonia Apartments
2.0 out of 5.0
Last booking: 5 hours ago
Crown Suites
4.0 out of 5.0
Last booking: 5 hours ago
Kima Villa
3.0 out of 5.0
Last booking: 5 hours ago