Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Map

Indulge your every desire on your impending sabbatical. After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made Santorini Island so popular in the last year. As you might have known, this is one of the Top 100 locations in Expedia's portfolio! You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Our 5-star hotels in Santorini Island are the perfect places to relax in when you really need to escape. You deserve the great vacation you're dreaming about.

Book the Best Santorini Island 5-Star Hotels

You'll have a fantastic time at one of these 5-star hotels. Michelin-starred restaurants, exceptional customer care, and rejuvenating spa offerings are waiting for you. We have a huge number of hotels in the area, and all of them offer outstanding amenities. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What creature comforts do you want in your lodging? A full-body massage to help your cares fall away? A concierge to help you make reservations at that outstanding restaurant? Plush carpeting, lip-smacking main courses, and even a hot tub in the bathroom...these hotels will leave you amazed.

But you aren't going to spend your entire vacation in your room, of course. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Santorini Island are the perfect place to relax after an exciting day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Santorini Island 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Don't put off your dream vacation any longer -- this is a great time to find 5-star hotel deals in @region! Select one of Expedia's Santorini Island 5-star hotels today and relax in the lap of luxury at your convenience.