Customized for your search:

Best 5 Star Hotels in St. Louis

St. Louis hotels
St. Louis

More St. Louis 5 Star Hotels

Four Seasons Hotel St Louis - St. Louis Hotels
Rating: 5.0 Stars
Check availability

Four Seasons Hotel St Louis

999 North Second Street, St. Louis 63102 - Map
"Excellent view of the Arch"
We had an excellent stay. Loved the location, the food and the view.
Traveller from Fontana, CA
This 19-story St. Louis hotel overlooks the Mississippi River, 3 blocks away. Shopping at Lumière Place is downstairs …More

Search from 1 St. Louis Hotels - 5 Stars

    Need help booking?

    Call 1-800-551-2409
    Visit Customer Support »

    Why book with Expedia ?

    • 282,000+ hotels worldwide
    • No Expedia Cancellation Fee
    • Best price guarantee
    • 91% customer satisfaction

    Find The Best Hotels in St. Louis

    Areas of St. Louis

    St. Louis Five Star Hotel Information

    Book private stadium tours and tickets to the symphony for a ritzy trip to St. Louis, Missouri.

    • Choose a fancy 5-star hotel in St. Louis that suits your high-end preferences
    • Earn perks for your loyalty through the Expedia+ program
    • Avoid spending a fortune when you book the cheapest hotel deals around
    Read More

    Treat yourself to the luxurious side of St. Louis.

    Score the best seats in the house for a performance at the Opera Theatre of Saint Louis, and feel like a VIP when you receive a private tour of the Cardinals baseball stadium. During your sojourn, revel in a fancy charter cruise along the Mississippi River with unrivaled views of the Gateway Arch, and listen to the sweet sounds of the St. Louis Symphony at Powell Hall. Whether a luxe vacation means pampering yourself with a massage at one of the best spas in downtown or dining at an upscale restaurant on the riverfront, you’ll find it all right here in The Lou. Make a reservation at one of the 5-star hotels in St. Louis to continue your classy indulgences all vacation long.

    Here at, we’re committed to providing you with the lavish getaway you desire at prices that won’t hurt your savings account. Take a look at our cheap deals on St. Louis 5-star hotels that pull out all the glamorous stops. You’ll find hotels with tranquility pools and steam rooms for the ultimate vacation experience. Sort through our selection of lodging today to discover everything from romantic places to luxury hotels in St. Louis that match all your high-class preferences.

    Customers Rate Expedia
    Powered by feefo
    91% recommended
    From 29,939 Reviews