
Cairo Vacations from $321
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Your Cairo Vacation
The exciting city of Cairo is calling. Discover its hot spots and hidden treasures with a Cairo vacation package that's custom made for you. Need some ideas on what to do or see first during your trip to Cairo? Head straight for famous attractions like Fort Defiance State Park. No matter your travel plans or the size of your budget, putting together a tailored Cairo vacation is simple with Expedia.
The Latest Cairo vacation packages
Price found within the past 48 hours. Click for updated prices.

Days Inn by Wyndham Oak Grove/Ft. Campbell
Price was $363, price is now $321 per person
$321
per person
Mar 12 - Mar 17
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Paducah (PAH)
7.2/10 Good! (232 reviews)
Room was clean and nice. Amenities were lacking. Bottles in shower were either stopped up or empty. They did have three tiny bottles on the sink but not enough for two persons. They did have baskets of shampoo & conditioner on the end of the counter in the offices but no one mentioned them and they had no body wash there. I didn’t notice them until later! Did not like kiosk check in and out. One other thing, if you have your iPhone near your door card, it erases your entry and you have to get someone to let you in.
Reviewed on Nov 28, 2025

Holiday Inn Hotel & Suites Hopkinsville - Convention Ctr by IHG
Price was $520, price is now $453 per person
$453
per person
Mar 12 - Mar 17
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Paducah (PAH)
9.2/10 Wonderful! (169 reviews)
Everything was great, the room was very nice , the service was excellent and our requests were met in a timely manner. We visit Hopkinsville often, and would not consider staying with anyone else. Keep up the great work
Andre & lillie
Reviewed on Dec 8, 2025

Holiday Inn Express Fort Campbell-Oak Grove by IHG
Price was $458, price is now $402 per person
$402
per person
Mar 12 - Mar 17
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Paducah (PAH)
8.8/10 Excellent! (605 reviews)
Room was clean and staff was very nice. This was my second stay and I will come back again.
Reviewed on Dec 14, 2025


Quality Inn Fort Campbell
Price was $371, price is now $341 per person
$341
per person
Mar 12 - Mar 17
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Paducah (PAH)
8.2/10 Very Good! (171 reviews)
Our room and the other facilities were clean and appeared to have been recently updated. The staff was friendly and helpful. We had a perfect overnight stay during our travels.
Reviewed on Jan 3, 2026
Discover the most popular places to visit in Cairo
Fort Defiance State Park
You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.
Cairo Hotel Deals

Quality Inn Cairo I-57
13201 Kessler Road Cairo IL
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $79 total per night from Jan 17 to Jan 18
$79 total
Jan 17 - Jan 18
Total with taxes and fees
6.4/10 (275 reviews)
Break fast was excellent
Reviewed on Sep 28, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $69 total per night from Jan 8 to Jan 9
$69 total
Jan 8 - Jan 9
Total with taxes and fees
6.6/10 (616 reviews)
Thank you
Reviewed on Nov 7, 2025

The Rested Duck Mallard Room
Olive Branch IL
$133 nightly
The price is $140 total per night from Jan 8 to Jan 9
$140 total
Jan 8 - Jan 9
Total with taxes and fees
9.2/10 Wonderful! (25 reviews)
It was fine. It was fairly clean and the bed was comfortable. No where to put anything down in the bathroom.
Reviewed on Oct 19, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Cairo Vacation Packages
Cairo Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Cape Girardeau Municipal Airport (CGI) |
Population | 2,500 |
Max Temp Winter | 45ºF |
Max Temp Summer | 85ºF |
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