Cairo Vacations from $585

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Your Cairo Vacation

The exciting city of Cairo is calling. Discover its hot spots and hidden treasures with a Cairo vacation package that's custom made for you. Need some ideas on what to do or see first during your trip to Cairo? Head straight for famous attractions like Fort Defiance State Park. No matter your travel plans or the size of your budget, putting together a tailored Cairo vacation is simple with Expedia.

The Latest Cairo vacation packages

Price found within the past 48 hours. Click for updated prices.
Regency Inn

Regency Inn

2 out of 5
per person
Nov 4 - Nov 9
found 4 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
8.4/10 Very Good! (320 reviews)
Nice room, affordable to spend the night.

Reviewed on Aug 8, 2025

Marcs Museum

Marcs Museum

3 out of 5
per person
Nov 4 - Nov 9
found 4 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
No reviews
Harrah's Metropolis Hotel & Casino

Harrah's Metropolis Hotel & Casino

3.5 out of 5
per person
Nov 4 - Nov 9
found 4 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
8.4/10 Very Good! (1,001 reviews)
Good food. Enjoyed the casino. Spacious rooms and bathroom.

Reviewed on Aug 17, 2025

The Respite Bed and Breakfast

The Respite Bed and Breakfast

4.5 out of 5
per person
Nov 4 - Nov 9
found 4 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
9.8/10 Exceptional! (236 reviews)
Could not control air in our room. We stayed during the first week of August. It was hot and wish we had a thermostat in room to turn air conditioning temperature down.

Reviewed on Aug 9, 2025

The Lakehouse Inn at Sledd Creek

The Lakehouse Inn at Sledd Creek

2 out of 5
per person
Nov 4 - Nov 9
found 4 hours ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
9.8/10 Exceptional! (118 reviews)
The décor at Lakehouse Inn is very charming. The room was spacious and very clean. The kitchenette in the room was small but very nicely stocked with anything we needed. The pool area is beautiful, and we enjoyed the DJ very much. The staff at the Inn was wonderful. Nevaeh was friendly and efficient, and made sure we had everything we needed. We will definitely stay there again.

Reviewed on Jul 11, 2025

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Discover the most popular places to visit in Cairo

Fort Defiance State Park

You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.

Fort Defiance State Park

Cairo Hotel Deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road, Cairo, IL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Sep 8 to Sep 9
$77 total
Sep 8 - Sep 9
Total includes taxes and fees
6.4/10 (264 reviews)
"The checkin was fast and easy. The room is big and comfortable."

Reviewed on Aug 6, 2025

Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St, Charleston, MO
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Sep 8 to Sep 9
$65 total
Sep 8 - Sep 9
Total includes taxes and fees
6.6/10 (580 reviews)
"Located very close to the expanse of corn fields, quiet, clean rooms, everything is neat, the bathroom is also very clean. Friendly receptionist."

Reviewed on Aug 1, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City
$175 nightly
The price is $185 total per night from Aug 20 to Aug 21
$185 total
Aug 20 - Aug 21
Total includes taxes and fees
9.8/10 Exceptional! (15 reviews)
"This place is beautiful and VERY CLEAN. Super secluded, but with a dollar store close enough if you forget to bring anything. Although if you are bringing a dog that might take the occasional toilet sip in unfamiliar places, make sure to enter the cabin ahead of them and close the toilet lid or bathroom ..."

Reviewed on Aug 14, 2025

Peaceful secluded cabin located near Horseshoe Lake
See all 24 properties in Cairo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Cairo vacation package cost?
Offering great value package deals from $585 on Expedia, you'll be pleasantly surprised at how much a vacation to Cairo costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Cairo?
If you'd like to snag a cheap Cairo vacation package, consider planning a trip in December, January and February. You'll typically find lower prices on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Cairo?
The ideal duration for your Cairo vacation depends on what you'd like to do. Generally, a few days to a week will give you plenty of time to go to all the major attractions and explore some hidden treasures along the way.
How to find the best Cairo package deals?
Landing a cheap Cairo package deal is a cinch with Expedia. Once you've entered your trip dates and destination under our "Packages" tab, set your budget range, apply some filters and see what's available. You can fine-tune your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to view the most economical Cairo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Cairo vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging accommodations and flights individually. Better still, you can customize your Cairo escape to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Cairo?
Score amazing discounts by reserving your flights in advance with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for a spur-of-the-moment Cairo break.
Does Expedia offer Book Now, Pay Later Cairo vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Cairo vacation across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.