Cairo Vacations from $531

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Your Cairo Vacation

The exciting city of Cairo is calling. Discover its hot spots and hidden treasures with a Cairo vacation package that's custom made for you. Need some ideas on what to do or see first during your trip to Cairo? Head straight for famous attractions like Fort Defiance State Park. No matter your travel plans or the size of your budget, putting together a tailored Cairo vacation is simple with Expedia.

The Latest Cairo vacation packages

Price found within the past 48 hours. Click for updated prices.
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

3.5 out of 5
Price was $696, price is now $531 per person
$531
per person
Jan 10 - Jan 13
found 24 hours ago
Roundtrip non-stop flight included
Houston (HOU) to Paducah (PAH)
16.4/10 Exceptional! (1,000 reviews)
Other than loosing my money it was a nice stay👍

Reviewed on Nov 11, 2025

Marcs Museum

Marcs Museum

3 out of 5
Price was $842, price is now $704 per person
$704
per person
Jan 10 - Jan 13
found 24 hours ago
Roundtrip non-stop flight included
Houston (HOU) to Paducah (PAH)
No reviews
Belle Louise Historic Guest House

Belle Louise Historic Guest House

3.5 out of 5
Price was $758, price is now $689 per person
$689
per person
Jan 10 - Jan 13
found 24 hours ago
Roundtrip non-stop flight included
Houston (HOU) to Paducah (PAH)
20/10 Exceptional! (11 reviews)
Beautiful house with fantastic hosts. Thoroughly enjoyed our stay.

Reviewed on Sep 14, 2025

Homewood Suites By Hilton Paducah

Homewood Suites By Hilton Paducah

3 out of 5
Price was $647, price is now $592 per person
$592
per person
Jan 10 - Jan 13
found 24 hours ago
Roundtrip non-stop flight included
Houston (HOU) to Paducah (PAH)
18.8/10 Exceptional! (391 reviews)
Excellent option for a road trip! Great job team! Kudos!

Reviewed on Oct 26, 2025

Hampton Inn & Suites Paducah

Hampton Inn & Suites Paducah

2.5 out of 5
Price was $625, price is now $575 per person
$575
per person
Jan 10 - Jan 13
found 24 hours ago
Roundtrip non-stop flight included
Houston (HOU) to Paducah (PAH)
18.4/10 Exceptional! (562 reviews)
Great staff, clean room and quiet

Reviewed on Nov 22, 2025

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Discover the most popular places to visit in Cairo

Fort Defiance State Park

You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.

Fort Defiance State Park

Cairo Hotel Deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road Cairo IL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $76 total per night from Nov 30 to Dec 1
$76 total
Nov 30 - Dec 1
Total with taxes and fees
6.4/10 (272 reviews)
Break fast was excellent

Reviewed on Sep 28, 2025

Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $59 total per night from Nov 24 to Nov 25
$59 total
Nov 24 - Nov 25
Total with taxes and fees
6.6/10 (607 reviews)
Thank you

Reviewed on Nov 7, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 out of 5
102 Drake St Charleston MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Nov 30 to Dec 1
$73 total
Nov 30 - Dec 1
Total with taxes and fees
6.8/10 (406 reviews)
Ladydi
The only issue was the temperature display on the ac/heating unit went to E5 during the night and it was overly warm. I woke up because of this and was able to get the fan only running but it was still uncomfortable for me and I spent 5 hours tossing and turning with little sleep after that with ...

Reviewed on Oct 22, 2025

Quality Inn Charleston - Sikeston
See all 25 properties in Cairo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Cairo Vacation Packages

Cairo Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cape Girardeau Municipal Airport (CGI)
Population
2,500
Max Temp Winter
45ºF
Max Temp Summer
85ºF

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Frequently asked questions

How much does a Cairo vacation package cost?
Offering great value package deals from $531 on Expedia, you'll be pleasantly surprised at how much a vacation to Cairo costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Cairo?
If you'd like to snag a cheap Cairo vacation package, consider planning a trip in December, January and February. You'll typically find lower prices on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Cairo?
The ideal duration for your Cairo vacation depends on what you'd like to do. Generally, a few days to a week will give you plenty of time to go to all the major attractions and explore some hidden treasures along the way.
How to find the best Cairo package deals?
Landing a cheap Cairo package deal is a cinch with Expedia. Once you've entered your trip dates and destination under our "Packages" tab, set your budget range, apply some filters and see what's available. You can fine-tune your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to view the most economical Cairo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Cairo vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging accommodations and flights individually. Better still, you can customize your Cairo escape to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Cairo?
Score amazing discounts by reserving your flights in advance with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for a spur-of-the-moment Cairo break.
Does Expedia offer Book Now, Pay Later Cairo vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Cairo vacation across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.