Cairo Vacations from $390

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Your Cairo Vacation

The exciting city of Cairo is calling. Discover its hot spots and hidden treasures with a Cairo vacation package that's custom made for you. Need some ideas on what to do or see first during your trip to Cairo? Head straight for famous attractions like Fort Defiance State Park. No matter your travel plans or the size of your budget, putting together a tailored Cairo vacation is simple with Expedia.

The Latest Cairo vacation packages

Price found within the past 48 hours. Click for updated prices.
Comfort Suites Hopkinsville near Fort Campbell

Comfort Suites Hopkinsville near Fort Campbell

2.5 out of 5
Price was $448, price is now $390 per person
$390
per person
Oct 10 - Oct 13
found 1 day ago
Roundtrip flight included
Minneapolis (MSP) to Paducah (PAH)
9/10 Wonderful! (506 reviews)
The Comfort Inn was awesome, clean, and everyone was friendly, considering I stayed in a Hilton in Clarksville, TN, and it wasn't very good. Comfort Inn beat them by a mile. Thanks for the awesome service and clean room.

Reviewed on Jul 29, 2025

Harrah's Metropolis Hotel & Casino

Harrah's Metropolis Hotel & Casino

3.5 out of 5
Price was $784, price is now $668 per person
$668
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
8.4/10 Very Good! (1,001 reviews)
Excellent hotel for the overnight stay

Reviewed on Aug 19, 2025

The Respite Bed and Breakfast

The Respite Bed and Breakfast

4.5 out of 5
Price was $874, price is now $745 per person
$745
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
9.8/10 Exceptional! (242 reviews)
Could not control air in our room. We stayed during the first week of August. It was hot and wish we had a thermostat in room to turn air conditioning temperature down.

Reviewed on Aug 9, 2025

La Quinta Inn & Suites by Wyndham Paducah

La Quinta Inn & Suites by Wyndham Paducah

3 out of 5
Price was $767, price is now $668 per person
$668
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
8.8/10 Excellent! (1,008 reviews)
The pool area was a mess, outdoor patio cushions were out by the railroad tracks. Stained carpet in our room.

Reviewed on Aug 23, 2025

Regency Inn

Regency Inn

2 out of 5
Price was $656, price is now $575 per person
$575
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Detroit (DTW) to Paducah (PAH)
8.4/10 Very Good! (322 reviews)
Nice room, affordable to spend the night.

Reviewed on Aug 8, 2025

Don't see what you're looking for?
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Discover the most popular places to visit in Cairo

Fort Defiance State Park

You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.

Fort Defiance State Park

Cairo Hotel Deals

Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 out of 5
13201 Kessler Road, Cairo, IL
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $77 total per night from Sep 11 to Sep 12
$77 total
Sep 11 - Sep 12
Total with taxes and fees
6.4/10 (264 reviews)
"The checkin was fast and easy. The room is big and comfortable."

Reviewed on Aug 6, 2025

Quality Inn Cairo I-57
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St, Charleston, MO
Fully refundableReserve now, pay when you stay
$58 nightly
The price is $64 total per night from Sep 8 to Sep 9
$64 total
Sep 8 - Sep 9
Total with taxes and fees
6.6/10 (584 reviews)
Big rooms
"We stay here a lot. It is conveniently located. We like the nice big rooms."

Reviewed on Aug 21, 2025

Super 8 by Wyndham Charleston/Sikeston East MO
Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake

Miller City
$175 nightly
The price is $185 total per night from Aug 24 to Aug 25
$185 total
Aug 24 - Aug 25
Total with taxes and fees
9.8/10 Exceptional! (17 reviews)
"Out of the way location was just the solitude I needed! Thank you for sharing your home with us."

Reviewed on Aug 15, 2025

Peaceful secluded cabin located near Horseshoe Lake
See all 24 properties in Cairo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Cairo vacation package cost?
Offering great value package deals from $390 on Expedia, you'll be pleasantly surprised at how much a vacation to Cairo costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Cairo?
If you'd like to snag a cheap Cairo vacation package, consider planning a trip in December, January and February. You'll typically find lower prices on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Cairo?
The ideal duration for your Cairo vacation depends on what you'd like to do. Generally, a few days to a week will give you plenty of time to go to all the major attractions and explore some hidden treasures along the way.
How to find the best Cairo package deals?
Landing a cheap Cairo package deal is a cinch with Expedia. Once you've entered your trip dates and destination under our "Packages" tab, set your budget range, apply some filters and see what's available. You can fine-tune your search by "Area," "Amenities," "Property type" and more. Sort the results by "Price: low to high" to view the most economical Cairo package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
Is it cheaper to book a Cairo vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging accommodations and flights individually. Better still, you can customize your Cairo escape to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Cairo?
Score amazing discounts by reserving your flights in advance with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for a spur-of-the-moment Cairo break.
Does Expedia offer Book Now, Pay Later Cairo vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Cairo vacation across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.