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Find Hotels in Cape Girardeau, MO

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Serenity South -- Gardens, River-views, and Refreshing Space
The price is $150 per night
3.84 mi from city center
4.9/5Exceptional! (9 reviews)
Great Getaway

"Close proximity to shops/ restaurants (next door to a spa) - this property will not disappoint- (in particular if you appreciate old world charm- with modern amenities)- Highly recommend !!!"…"

Reviewed on May 20, 2020

Serenity South -- Gardens, River-views, and Refreshing Space
Loft Apartment Across From Semo University Houch Field House. Walk To Events
The price is $150 per night
3.03 mi from city center
4.8/5Exceptional! (25 reviews)
Very nice

"Big apartment. Owners were wonderful to work with."…"

Reviewed on Jul 1, 2020

Loft Apartment Across From Semo University Houch Field House. Walk To Events
Quality Inn
2.5 out of 5
2011 North Kingshighway, Cape Girardeau, MO
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0.7 mi from city center
3.4/5 (358 reviews)
Exceptionally good

"Nice friendly people peace and quiet atmosphere"…"

Reviewed on Oct 22, 2019

Quality Inn
Drury Plaza Hotel Cape Girardeau Conference Center
3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Free CancellationReserve now, pay when you stay
The price is $100 per night
1.42 mi from city center
4.8/5Exceptional! (442 reviews)

"The front desk clerks were great checking and out. the room had great view and very big- however i was not pleased with the noise of alot of kids in the next room. (i was told that there was a tournament of some sort) and my Tub had a stain in it."…"

Reviewed on Jun 29, 2020

Drury Plaza Hotel Cape Girardeau Conference Center
Historical 'kage House' Short Term Rental Located in "old Town Cape"
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3.78 mi from city center
4.9/5Exceptional! (159 reviews)
Perfect Getaway

"Great location, clean and relaxing property. Perfect for a few days of relaxation. Super close to everything g that Cape has to offer."…"

Reviewed on Jun 29, 2020

Historical 'kage House' Short Term Rental Located in "old Town Cape"
Drury Inn & Suites Cape Girardeau
3 out of 5
3303 Campster Drive, Cape Girardeau, MO
Free CancellationReserve now, pay when you stay
The price is $90 per night
1.7 mi from city center
4.7/5Exceptional! (403 reviews)

"Clean room nice staff. Breakfast and dinner, with free drinks"…"

Reviewed on Jun 30, 2020

Drury Inn & Suites Cape Girardeau
Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 out of 5
3248 William St, Cape Girardeau, MO
Free CancellationReserve now, pay when you stay
The price is $65 per night
1.69 mi from city center
4.2/5Excellent! (958 reviews)

"This was a clean and comfortable room and the staff were very nice and helpful. I also appreciated that the pool was open."…"

Reviewed on Jun 24, 2020

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau West
2.5 out of 5
103 Cape West Pkwy, Cape Girardeau, MO
Free CancellationReserve now, pay when you stay
The price is $65 per night
1.68 mi from city center
4.3/5Excellent! (673 reviews)

"AMAZING employees. Patti went above and beyond for me and I couldn't have had a better stay without her help"…"

Reviewed on Jun 20, 2020

Pear Tree Inn Cape Girardeau West
Downtown Historic Apartment
Cape Girardeau, MO
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3.8 mi from city center
No reviews
Love the beautiful views

"It is very spacious and relaxing"…"

Reviewed on May 22, 2019

Downtown Historic Apartment
Serenity North - Enclosed Gardens and Pet-friendly Space
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3.82 mi from city center
5/5Exceptional! (2 reviews)
Nice location!

"It was great being able to walk to the restaurants and shops. Nice area. Bathrooms are a bit tight, but nice. I would have liked a queen bed in the bigger bedroom, but I knew what I reserved ahead of time. Property manager was quick to respond to any questions before the stay. There were cookies ..."…"

Reviewed on Feb 18, 2020

Serenity North - Enclosed Gardens and Pet-friendly Space
You Have the Entire House
Cape Girardeau, MO
The price is $180 per night
2.49 mi from city center
4.8/5Exceptional! (4 reviews)
Great little house!

"We really enjoyed our stay at the Dunklin house! The house decor is very cute, especially the painted floor in the living room! I want to do that in my basement! The house was super clean and comfortable. No complaints at all!"…"

Reviewed on Nov 21, 2017

You Have the Entire House
Town House Inn Cape Giradreau
2.5 out of 5
505 North Kingshighway Street, Cape Girardeau, MO
Free CancellationReserve now, pay when you stay
The price is $60 per night
1.8 mi from city center
2.9/5 (82 reviews)

"Management is wonderful, convenient location."…"

Reviewed on Mar 20, 2020

Town House Inn Cape Giradreau
Courtyard by Marriott Cape Girardeau Downtown
3 out of 5
400 Broadway St., Cape Girardeau, MO
Free CancellationReserve now, pay when you stay
The price is $107 per night
3.54 mi from city center
4.7/5Exceptional! (95 reviews)

"Very nice and clean room. Close to the older downtown area and the river and not near the newer section with more amenities by the freeway but I was aware of that when I booked so didn’t mind but some people might. One feature I really liked was the TV could access my Netflix and Amazon accounts ..."…"

Reviewed on Jun 28, 2020

Courtyard by Marriott Cape Girardeau Downtown
Drury Inn & Suites Jackson MO
3 out of 5
225 Drury Lane, Jackson, MO
Free CancellationReserve now, pay when you stay
The price is $83 per night
7.79 mi from city center
4.7/5Exceptional! (562 reviews)

"It was a quiet and clean place to stay. The staff was friendly and helpful."…"

Reviewed on Jun 21, 2020

Drury Inn & Suites Jackson MO
Historic Downtown Getaway
Cape Girardeau, MO
Get Rates
3.66 mi from city center
5/5Exceptional! (5 reviews)
Really Relaxing!

"My husband and I really enjoyed everything about this location and property. This probably was the best appointed home/vrbo we have stayed in. Everything was so comfortable and a great location. Thank you so much to the owners to make sure we had everything we needed with our stay."…"

Reviewed on Nov 8, 2019

Historic Downtown Getaway
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Visiting Cape Girardeau

Families will find kid-friendly activities in Cape Girardeau, and visitors give high marks for the top-notch restaurants. Tourists who journey to this welcoming city can discover its riverfront, university setting, and shopping. Top sights in the city include Isle Casino Cape Girardeau and Shawnee National Forest.

  • You'll find 39 Expedia hotels and other accommodations in the larger area of Sikeston
  • The closest major airport is in Cape Girardeau, MO (CGI-Cape Girardeau Municipal), 7 mi (11.2 km) from the city center
  • The next closest is in Cairo, IL (CIR-Cairo Regional), 26.9 mi (43.3 km) away

Sightseeing and Staying in Cape Girardeau

Favorite family attractions include Cape Girardeau Conservation Nature Center and Cape Splash Family Aquatic Center. The city's natural setting is picturesque, including the riverfront and Shawnee National Forest. The university setting is a highlight of the city and Southeast Missouri State University is worth a campus tour.

As you plan your holiday getaway, you'll find 18 hotels and other lodging options to select from in Cape Girardeau. These are top ranked ones based on our user reviews:

Other top sights in Cape Girardeau include Isle Casino Cape Girardeau.

Dressing for Cape Girardeau

  • Between January and March, you can expect average temperatures of 64°F during the day and 24°F at night
  • From April to June, the average during the day is 89°F, while the average at night is 40°F
  • July through September has daytime averages of 89°F with nighttime averages of 50°F
  • In October-December, you can expect daytime averages of 75°F and nighttime averages of 24°F
  • Average annual rainfall for Cape Girardeau is 46.81 inches
  • Usually July and August are the hottest months with an average of 89°F, whereas January and December are often coldest, averaging 26°F

Frequently asked questions

What's the best place to stay in Cape Girardeau?
Drury Plaza Hotel Cape Girardeau Conference Center is a favorite property for Expedia customers. This 3-star hotel offers free breakfast and a restaurant. Other favorite options based on traveler reviews include Hampton Inn Cape Girardeau I 55 East and Holiday Inn Express Hotel & Suites Cape Girardeau I-55.
If I need to cancel my hotel reservation in Cape Girardeau, will I receive a refund?
Yes, the majority of room reservations are fully refundable provided that you cancel prior to the hotel’s cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that’s non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on “Search”, then you can use the “free cancellation” filter to review the top deals on offer in Cape Girardeau.
Where can I learn more about changing or cancelling my trip to Cape Girardeau?
For more details about picking new dates or cancelling your trip to Cape Girardeau, head over to our customer service page.
What's the best budget-friendly accommodation in Cape Girardeau?
Based on reviews, Auburn Place Hotel And Suites is a popular 2.5-star hotel for our travelers looking for an economical choice, and features free buffet breakfast and free WiFi. Other good options to stay on the cheap include Pear Tree Inn Cape Girardeau West and Quality Inn.
What's the best hotel for families in Cape Girardeau?
Pear Tree Inn Cape Girardeau West is a hotel with free parking and free breakfast, and it’s a top choice on Expedia for families. Other good choices to stay with the kids include Pear Tree Inn Cape Girardeau Near the Medical Center and Quality Inn. Attractions like Cape Girardeau Conservation Nature Center and Cape Splash Family Aquatic Center are also fun for kids of all ages.
What's the best pet-friendly hotel in Cape Girardeau?
Candlewood Suites Cape Girardeau is a top hotel for people traveling with their pets, and offers an indoor pool and in-room kitchens for its human guests. Other good choices to stay with your pet include Auburn Place Hotel And Suites and Drury Inn & Suites Cape Girardeau.
Where is the best hotel to stay with easy access to Isle Casino Cape Girardeau?
Pear Tree Inn Cape Girardeau West is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free WiFi. It’s located 3.5 mi (5.6 km) from Isle Casino Cape Girardeau. Other good options within a few miles include Auburn Place Hotel And Suites and Pear Tree Inn Cape Girardeau Near the Medical Center.
What about the best place to stay close to Southeast Missouri State University?
One of the top choices for your stay is Pear Tree Inn Cape Girardeau West, located 3.3 mi (5.3 km) from Southeast Missouri State University, and this hotel offers free breakfast and free WiFi. Auburn Place Hotel And Suites and Pear Tree Inn Cape Girardeau Near the Medical Center are two other good choices within 5 miles.
What's the best accommodation in Cape Girardeau that's close to historical sites?
Based on our travel expertise, Historical ‘kage House’ Short Term Rental Located in “old Town Cape” is a top historic apartment bookable on our site and it features in-room kitchens.
What are some accommodations with pools in Cape Girardeau?
Pear Tree Inn Cape Girardeau Near the Medical Center is a top hotel with an outdoor pool, free breakfast, and free WiFi. A couple of other options with an onsite pool include Quality Inn and Drury Plaza Hotel Cape Girardeau Conference Center.

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