Beginning of main content

Adventure Hotels in Cape Girardeau

Search Flights

Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Cape Girardeau Hotels

Search Flight + Hotel

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Cape Girardeau Adventure Hotels

See all 20 Hotels in Cape Girardeau
Holiday Inn Express Hotel & Suites Cape Girardeau I-55

Holiday Inn Express Hotel & Suites Cape Girardeau I-55

3253 William Street, Cape Girardeau
2.5 out of 5.0
4.8 out of 5 (80 reviews)
MovingReally enjoyed the friendly staff! The room are super clean. Who doesn't love a good breakfast to start your day?!
  Jun 5, 2017

$106

$106
Map

Recently booked Cape Girardeau hotels

Pear Tree Inn Cape Girardeau Near the Medical Center
2.0 out of 5.0
Last booking: 6 hours ago
Drury Suites Cape Girardeau
3.0 out of 5.0
Last booking: 15 hours ago
Pear Tree Inn Cape Girardeau West
2.5 out of 5.0
Last booking: 17 hours ago
Hampton Inn Cape Girardeau I 55 East
2.5 out of 5.0
Last booking: 25 hours ago

Pocket Guide: Adventure Hotels in Cape Girardeau

Search for hotels in Cape Girardeau on Expedia. You can easily find your hotels in Cape Girardeau using one of the methods below:

  • View our selection of featured hotels in Cape Girardeau
  • Use the map to find hotels in the Cape Girardeau neighborhood you prefer
  • Use the filters to see hotels in a specific area of Cape Girardeau, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Cape Girardeau
  • Enter your travel dates to view the best deals on hotels in Cape Girardeau - while they last