Search over 1,000,000 properties worldwide and 550 airlines worldwide.
Search over a million flights, hotels, packages, and more
No Expedia cancellation fee to change or cancel almost any hotel reservation.
Last year, journeys to Panama City were popular. In fact, Panama City is so fantastic that scores of folks have put down roots here. When you get to Panama City, you'll have your eye on new excursions and an exciting itinerary ready to go. You could depend on public transportation to make your way around after you check into your hotel. Or, you can always get into the taxi queue after you deplane and grab your luggage. Plus, oftentimes traveling through the city center is easiest done on foot. We say you should wave goodbye to staying beholden to the public transit route and hello to the benefits of a private ride. Renting a car gives you more independence during your vacation. When you're behind the wheel, you can sightsee in Panama City on your desired timetable.
Browse our inventory for a smaller car that is easy to handle, or turn the keys in a larger ride that can accommodate plenty of shopping bags in the back in the back--Expedia has a selection of cars to make any traveler smile searching for a great deal on car rentals in Panama City.Our fleet features vehicles for everyone from solo travelers to huge families. When you're deciding on Panama City rental cars on Expedia, your choices include:
Use Expedia's user-friendly booking widget to choose your travel dates and preferred vehicle, and your rental car is guaranteed within just a few minutes--locating a rental car in Panama City has never been easier! Now it's time to go shopping for a set of sunglasses for the ride and choose a hotel in the heart of Panama City. Let's get your adventure started!