Top 10 Hotels in Centerville, SC (from $59) 2026 - Competitive Prices

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Our top choices for Centerville hotels

A multi-level hotel atrium with a central open area, multiple balconies, and a variety of seating arrangements.

A large hotel with a central courtyard, surrounded by manicured lawns and trees.

An outdoor patio area with tables and chairs, a covered seating area, and a building in the background labeled "Embassy Suites."

A spacious lobby with multiple seating areas, a glass railing overlooking a green space, and a modern interior design.

1. Embassy Suites Greenville Golf Resort & Conference Center

Greenville

Edwin

$108 nightly

$120 total

Oct 18 - Oct 19

Total with taxes and fees

A spacious lobby with modern furniture, a chandelier, and potted plants.

An outdoor seating area with tables and chairs, potted plants, and a modern building facade.

2. Hilton Greenville

Greenville

Kenneth W

$111 nightly

$122 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a large bed, a desk, a chair, a bathtub, and a large window.

A modern kitchen with a long counter, built-in appliances, and a dining area with a table and chairs.

A picnic table in a forested area with a paved path nearby.

A modern hotel lobby with a reception desk, seating area, and a dining space.

3. Days Inn by Wyndham Anderson

Anderson

Amy

$59 nightly

$65 total

Oct 27 - Oct 28

Total with taxes and fees

A large, multi-story house with a prominent waterfall in the foreground, surrounded by lush greenery.

An outdoor dining area with multiple tables and chairs, large windows, and a view of greenery.

A modern interior with a stone fireplace, leather sofas, and a wooden ceiling.

A modern interior with a fireplace, plush seating, and a stone accent wall.

4. Grand Bohemian Lodge Greenville, Autograph Collection

Greenville Downtown

ALICE

$401 nightly

$441 total

Oct 11 - Oct 12

Total with taxes and fees

A spacious lobby with a central bar area, multiple seating options, and a distinctive ceiling structure.

A spacious bar area with a circular layout, multiple seating options, and a variety of bottles.

An outdoor dining area with a fire feature and a wall with the word "ROOST" illuminated.

A Hyatt Regency building with a modern facade, a landscaped entrance area, and a sign indicating the location.

5. Hyatt Regency Greenville

Greenville Downtown

Karen

$166 nightly

$182 total

Nov 8 - Nov 9

Total with taxes and fees

An indoor swimming pool with a tiled floor, a covered area, and a seating area with chairs.

A modern restaurant with high ceilings, large windows, and a mix of seating options including booths and tables.

A modern hotel lobby with a wooden cabinet, a flat-screen TV, a sofa, and a table.

A fitness center with treadmills, elliptical machines, and a red exercise ball.

6. Drury Inn & Suites Greenville

Greenville

Kara

$113 nightly

$124 total

Nov 1 - Nov 2

Total with taxes and fees

A modern bar area with a marble counter, houndstooth patterned chairs, and pendant lighting.

A spacious living area with a sofa, two armchairs, a coffee table, and a chandelier. Large windows provide a view of the outdoors.

A modern interior with round tables, houndstooth patterned chairs, a bar area, and a view through large windows.

A modern bar area with a marble countertop, houndstooth patterned chairs, and pendant lighting.

7. Holiday Inn Anderson by IHG

Anderson

Deirdre

$106 nightly

$118 total

Nov 8 - Nov 9

Total with taxes and fees

A spacious living room with a fireplace, large windows, and a flat-screen TV mounted above the mantel.

A seating area with wicker chairs, a coffee table, and a large floor lamp.

A hotel lobby with a reception desk, potted plants, and a tiled floor.

A multi-story hotel with a prominent entrance, a well-lit facade, and a parking area in front.

8. Hilton Garden Inn Anderson

Anderson

Ellen

$110 nightly

$122 total

Nov 8 - Nov 9

Total with taxes and fees

An outdoor patio area with a wooden pergola, barbecue grill, and seating.

A modern building with large windows and a brick facade at a street corner.

An indoor swimming pool with a brick wall backdrop, a poolside area with tables and chairs, and a clear pool edge.

A modern hotel lobby with a seating area featuring sofas and round tables, large windows, and a decorative wooden panel.

9. Homewood Suites by Hilton Greenville Downtown

Greenville Downtown

Lindsay

$151 nightly

$166 total

Nov 1 - Nov 2

Total with taxes and fees

A modern restaurant interior with round tables and chairs, a kitchen area, and large windows offering a view of parked cars outside.

A modern kitchen with a central island, three bar stools, pendant lighting, and a decorative flower arrangement.

A hotel room with a large bed, a desk with a chair, a blue armchair, a wooden nightstand with a lamp, and a wardrobe with a mirror.

A pool area with lounge chairs and a sign for Best Western Plus.

10. Best Western Plus Greenville I-385 Inn & Suites

Greenville

Christina

$78 nightly

$85 total

Oct 25 - Oct 26

Total with taxes and fees

An outdoor patio area with seating arrangements, including chairs and tables, and a covered section with a view of the street.

A hotel room with a bed, a sofa, a small table, a nightstand with a lamp, and a wall with a forest wallpaper.

A modern hotel lobby with a central seating area, multiple tables, and a chandelier.

A modern hotel lobby with a central seating area, a bar, and a television screen.

11. Home2 Suites by Hilton Anderson Downtown

Anderson

John

$140 nightly

$155 total

Nov 1 - Nov 2

Total with taxes and fees

A multi-story hotel with a modern design, featuring a mix of glass and brick facades, and a parking area with autumn-colored trees.

A modern hotel lobby with a reception desk, seating area, and a decorative wall.

A hotel room with a large bed, a TV, a desk, and a view of the city through large windows.

12. Hyatt Place Greenville Downtown

Greenville Downtown

Emily

$126 nightly

$138 total

Nov 1 - Nov 2

Total with taxes and fees

A modern hotel lobby with a bar area, seating, and a patterned floor.

A hotel entrance with a welcoming sign, a covered walkway, and a landscaped area with benches and flowers.

A hotel lobby with a reception desk, computers, and a seating area.

A hotel room with two beds, a desk, a TV, and a large window with curtains.

13. Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Greenville

Shauna Leigh

$93 nightly

$103 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel entrance with a stone facade, a wooden door, and potted plants.

A two-story building with a brick facade, a central entrance with a curved arch, and a balcony on the second floor.

A restaurant with wooden ceiling beams, stone walls, and red patterned curtains. Tables are set with white tablecloths and candles.

A living room with a fireplace, a television mounted above it, and two sofas with floral cushions.

14. The Bleckley Inn

Anderson

Chandler

$170 nightly

$189 total

Oct 11 - Oct 12

Total with taxes and fees

A modern hotel lobby with a reception desk, seating area, and a large conference table.

A snack display with various packaged foods in a store.

A modern hotel room with a bed, bedside tables, a desk, a chair, and a large window with a geometric curtain.

A multi-story hotel with a parking lot in front.

15. Microtel Inn & Suites by Wyndham Anderson/Clemson

Anderson

Tricia

$84 nightly

$93 total

Oct 14 - Oct 15

Total with taxes and fees

A modern hotel room with a large bed, a desk with a chair, a small table, and a nightstand with a lamp.

A coffee station with two coffee machines, a coffee press, and various coffee pods and cups.

A breakfast station with a toaster, a fruit bowl, and a bakery display.

A Holiday Inn Express & Suites hotel with a modern architectural design, featuring a prominent entrance with columns and a flat roof.

16. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Anderson

Heather

$106 nightly

$118 total

Nov 8 - Nov 9

Total with taxes and fees

A patio area with a round table and chairs, a fire pit, and a building with a stone facade and blue accents.

A modern hotel room with a flat-screen TV, a sofa, a small table, a bed, and a kitchenette area.

A modern hotel lobby with a reception desk, seating area, and a large chandelier.

A modern hotel lobby with a long communal table, seating areas, and a TV mounted on the wall.

17. Residence Inn by Marriott Anderson Clemson

Anderson

Jessica

$143 nightly

$159 total

Oct 18 - Oct 19

Total with taxes and fees

A hotel entrance with a modern design, featuring a prominent 'aloft' sign, a covered walkway, and decorative lighting.

A rooftop patio with a fire pit surrounded by red chairs, a modern building in the background, and a clear sky.

A hotel room with a wooden desk, a blue chair, and a TV.

A modern cafe with a central counter, multiple seating areas, and large windows.

18. Aloft by Marriott Greenville Downtown

Greenville Downtown

Jessica

$151 nightly

$167 total

Oct 25 - Oct 26

Total with taxes and fees

A multi-story hotel with a modern design, featuring balconies, large windows, and a reflection in the water.

A spacious restaurant with high ceilings, exposed beams, and large windows offering a view of the city. Tables are set with wine glasses and plates, ready for dining.

A spacious lobby with a round coffee table, patterned sofas, a large mirror, and a modern kitchen in the background.

A modern lobby with a curved gray sectional sofa, a round black coffee table, and a patterned rug.

19. Embassy Suites by Hilton Greenville Downtown Riverplace

Greenville Downtown

Jeniffer

$159 nightly

$176 total

Nov 1 - Nov 2

Total with taxes and fees

A poolside area with wicker furniture and a table, surrounded by a fence and greenery.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance, multiple floors, and a well-lit facade.

A corner market with a wooden interior, a glass door entrance, and a refrigerator display.

A modern living room with a stone wall, a fireplace, and a large window. There are two sofas, a coffee table, and a dining area with a table and chairs.

20. Fairfield Inn & Suites by Marriott Anderson Clemson

Anderson

jennifer

$98 nightly

$109 total

Oct 20 - Oct 21

Total with taxes and fees

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Stay near popular attractions around Centerville

Discover the charm of Centerville, where outdoor adventures and romantic scenery await. With beautiful parks and serene lakes, this destination is perfect for families and city explorers alike. Experience the best of nature and relaxation in a truly enchanting setting.

A kayak on calm water with a sunset in the background.

Lake Hartwell

9.2/10 (155 reviews)

Often cited as a favorite among nature lovers, Lake Hartwell offers stunning scenery and a romantic atmosphere perfect for a day of relaxation. Located about 11 miles from Centerville, this picturesque lake invites visitors to enjoy its beach vibes and outdoor activities, making it a great spot for a memorable getaway.

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A white flower with a yellow center surrounded by green leaves.

South Carolina Botanical Gardens

9.2/10 (133 reviews)

Perfectly suited for families and those seeking a romantic getaway, the South Carolina Botanical Gardens offers a stunning array of plants and vibrant landscapes. Located about 12 miles from Centerville, this serene oasis provides an ideal backdrop for leisurely strolls and outdoor activities, making it a convenient stop during your visit.

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Anderson University

8.6/10 (271 reviews)

Set the stage for your exploration of Anderson University, a historic college that exudes cultural vibes. Located about 4 miles from Centerville, this university offers a unique blend of academic heritage and community engagement, making it an inviting stop for visitors. Staying nearby provides easy access to its vibrant atmosphere.

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Anderson County Museum

7.8/10 (51 reviews)

Ideal for travelers interested in history, the Anderson County Museum offers a rich exploration of local heritage and culture. Located about 3 miles by car from Centerville, this museum invites you to delve into the region's past, making it a convenient stop during your visit.

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T. Ed Garrison Arena

7.4/10 (3 reviews)

Considered a premier spot for families seeking entertainment, T. Ed Garrison Arena offers a vibrant atmosphere filled with events and activities. Located about 10 miles from Centerville, it provides easy access for visitors. Staying nearby allows you to enjoy a fun-filled experience without hassle.

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Tri-County Technical College

10.0/10 (2 reviews)

Discover the appeal of Tri-County Technical College, a vibrant hub for prospective students and visitors alike. This modern institution boasts a lively atmosphere, perfect for exploring educational opportunities. Located about 12 miles by car from Centerville, it offers a convenient stop for those looking to experience local college life.

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NewSpring Church

7.4/10 (47 reviews)

A captivating destination for spiritual seekers, NewSpring Church offers vibrant cultural vibes in a welcoming atmosphere. Located about 6 miles from Centerville, it provides a unique experience filled with community engagement and inspiring services, making it a convenient stop for visitors looking to enrich their journey.

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Woodburn

A must-see for history buffs, Woodburn is a historic house that embodies the rich cultural heritage of South Carolina. Located about 11 miles away from Centerville by car, it offers a glimpse into the past while providing a serene atmosphere. Staying nearby allows for easy access to this charming site.

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Top Centerville Hotel Reviews

The Shepherd Hotel Downtown Clemson

10/10 Excellent

"lovely hotel and wonderful staff"

Comfort Suites Anderson-Clemson

10/10 Excellent

"Just right! Good breakfast."

Days Inn by Wyndham Anderson

10/10 Excellent

"Excellent stay! Staff was very friendly. Very clean and comfortable room. Great location."

Fairfield Inn & Suites Seneca Clemson Univ Area

10/10 Excellent

"Convenient location for doing business in seneca, and parts of clemson. The staff was wonderful. The breakfast was great."

Comfort Inn & Suites Clemson - University Area

10/10 Excellent

"room was clean and comfortable. bathywas a bit on the small size but doable. breakfast was normal and ok. staff was very friendly and accommodating."

Quality Inn Seneca US-123

8/10 Good

"Second time here! Staff great! This time my room smelled of smoke as a non smoking room! Comforter was clean but from a smoking room and smelled despite it being clean!"

The Inn at Patrick Square

10/10 Excellent

"Recommend this beautiful inn"

Woodspring Suites Anderson North I-85

8/10 Good

"Everything was great only thing I would make note of is the shower curtain had mold on it."

Horizon Inn & Suites

10/10 Excellent

"The pretty lady at the front desk is absolutely fabulous."