Find Adults Only Resorts & Hotels in Central United States from $78

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Our top choices for Central United States adults-only hotels

2 outdoor pools, free cabanas, sun loungers
Treasure Bay Casino and Hotel - Adults Only

Treasure Bay Casino and Hotel - Adults Only

3.5 star property
Biloxi
8.4 out of 10, Very Good, (1002)
"Great place to stay for the price!"
United States
Gary
$76 nightly
The price is $85
Dec 10 - Dec 11
Total with taxes and fees
Treasure Bay Casino and Hotel - Adults Only
Standard Studio, 1 Queen Bed, Non Smoking (Deluxe Studio Queen) | Living area | 65-inch flat-screen TV with cable channels, TV
EO Bungalows – Adults Only

EO Bungalows – Adults Only

3.0 star property
Custer
9.8 out of 10, Exceptional, (79)
"Love this place"
United States
Moriah
$88 nightly
The price is $97
Dec 10 - Dec 11
Total with taxes and fees
EO Bungalows – Adults Only
5 restaurants, breakfast, dinner served; American cuisine
Terre Haute Casino Resort

Terre Haute Casino Resort

4.0 star property
Terre Haute
9.2 out of 10, Wonderful, (709)
"Property was very clean and in excellent condition. Was a great stay. "
United States
Richard
$121 nightly
The price is $139
Dec 10 - Dec 11
Total with taxes and fees
Terre Haute Casino Resort
Grand Royal Pool Suite | Room amenity
Belamere Suites Hotel

Belamere Suites Hotel

3.5 star property
Perrysburg
9.4 out of 10, Exceptional, (150)
"Great stay"
United States
Unique
$219 nightly
The price is $247
Dec 10 - Dec 11
Total with taxes and fees
Belamere Suites Hotel
Casino
The Catfish Bend Inn & Spa

The Catfish Bend Inn & Spa

3.5 star property
Burlington
9.2 out of 10, Wonderful, (320)
"Staff was friendly and helpful. Accomodations were excellent."
United States
Phillip
$161 nightly
The price is $180
Dec 29 - Dec 30
Total with taxes and fees
The Catfish Bend Inn & Spa
Lobby
WaterView Casino & Hotel, Trademark Collection by Wyndham

WaterView Casino & Hotel, Trademark Collection by Wyndham

3.5 star property
Vicksburg
8.0 out of 10, Very Good, (1001)
"Great place"
United States
Sue
$82 nightly
The price is $90
Dec 10 - Dec 11
Total with taxes and fees
WaterView Casino & Hotel, Trademark Collection by Wyndham
Property grounds
The Lancaster Manor B&B

The Lancaster Manor B&B

3.5 star property
Gainesville
10.0 out of 10, Exceptional, (84)
"This place deserves 6 stars, John and Connie are truly outstanding people, every detail is meticulously taken care of, breakfast was perfect and everything is made from the scratch. This house does not feel like a hotel, feels like home ❤️"
United States
Nestor
$166 nightly
The price is $191
Jan 1 - Jan 2, 2026
Total with taxes and fees
The Lancaster Manor B&B
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Beaver Lakefront Cabins - Couples Only Getaways

Beaver Lakefront Cabins - Couples Only Getaways

4.0 star property
Sylvan Shores
10.0 out of 10, Exceptional, (252)
"Great place for a getaway for couples. "
United States
David
$172 nightly
The price is $188
Dec 10 - Dec 11
Total with taxes and fees
Beaver Lakefront Cabins - Couples Only Getaways
3 restaurants, breakfast, lunch, dinner served; seafood
Silver Slipper Casino & Hotel - Adults Only

Silver Slipper Casino & Hotel - Adults Only

3.5 star property
Bay St Louis
8.6 out of 10, Excellent, (1002)
"Perfect "
United States
CHAMAINE
$71 nightly
The price is $78
Dec 10 - Dec 11
Total with taxes and fees
Silver Slipper Casino & Hotel - Adults Only
Lobby
Ameristar Casino Hotel East Chicago

Ameristar Casino Hotel East Chicago

4.0 star property
East Chicago
8.6 out of 10, Excellent, (1008)
"Great stay in clean modern room."
United States
Douglas
$107 nightly
The price is $120
Jan 5 - Jan 6, 2026
Total with taxes and fees
Ameristar Casino Hotel East Chicago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Central United States Hotel Reviews

Frequently asked questions

How much do adults-only hotels in Central United States cost?
Adults-only properties in Central United States come in a variety of prices depending on the amenities provided and the type of room. Whatever your choice, you can enjoy all the youngster-free tranquility you need at a price that doesn't break the bank.
What are the best adults-only hotels in Central United States?
Central United States has 84 adults-only hotels with a total average guest review rating of 9.0. Organizing an escape to New York? Put your bags down at Incentra Village Hotel, a popular 3-star city base with individually decorated rooms and a garden. Ymca Harlem - Shared Bathroom is another top pick where you can have a blissful vacation without noisy kids and screaming babies. It has a 2-star rating and conveniences such as a terrace and a garden.
Are there any adult-only all-inclusive resorts in Central United States?
While there aren't any adults-only all-inclusive resorts or hotels in Central United States, this doesn't mean you can't enjoy a romantic escape with your special someone. Fall head over heels for Four Seasons Hotel New York Downtown, a popular New York stay which has amenities such as beauty services and a terrace. Hotel Giraffe by Library Hotel Collection is also loved by couples looking for a stay in New York. Reserve a room for two and enjoy perks like wedding services and a rooftop terrace.
What is there to do in Central United States near my adults-only hotel?
Whether you like food, shopping, history or sightseeing, Central United States has something to suit all tastes! The well-known city of New York has tons of attractions and experiences, including Rockefeller Center, Metropolitan Museum of Art and Museum of Modern Art. If you're headed to Chicago, Chicago Riverwalk Art Institute of Chicago and Shedd Aquarium should be at the top of your to-do list.
How can I find cheap adults-only hotels in Central United States?
With Expedia's handy filter tool, scoring cheap adults-only hotels in Central United States is a piece of cake. Simply refine your search results by budget, star rating and amenities to discover accommodations that'll make your wallet smile.
From what age can you stay in an adult-only hotel in Central United States?
The minimum age permitted may differ across properties, so be sure to check the rules of the adult-only hotel in Central United States you're considering. But typically, it's 16, 18 or 21. Whether you're searching for romantic evenings, a fun party atmosphere or just a break from parenting duties, our fantastic adult-only resorts and hotels are all about making grown-ups feel like VIPs.
Are all adult-only resorts all-inclusive in Central United States?
If you only plan to vacation at a resort or hotel where most of what you need is covered by the room rate, use our "all-inclusive" filter. This will display the available adult-only all-inclusive retreats in Central United States that typically include your room, drinks and food, a host of on-site activities and great entertainment. Click on the resort you have your eye on to see exactly what you'll get for the price.
Why book your adults-only hotel in Central United States with Expedia?
With affordable prices and an impressive selection of hotels in Central United States, Expedia is your one-stop travel site for an adults-only escape. Keep the budget under control and pick an all-inclusive stay, or treat your partner to a romantic getaway in a high-end hotel.
When is the best time to stay at an adult-only all-inclusive resort in Central United States?
Almost any time is a good time to stay at an adult-only all-inclusive hotel in Central United States, but there are a few things you'll want to think about. Start with the time of year you want to travel. Peak season is lively and popular, but there's a higher demand for both flights and accommodations. Low season tends to be less hectic and easier on the purse strings. Of course, the weather plays a part in making or breaking your getaway, so do a little research before booking your adult-only hotel or resort.
Can I cancel or change my adult-only resort booking?
Absolutely. And there may be no charge depending on the type of adult-only hotel or resort booking you made. Read the fine print in your itinerary or head over to Expedia's Trips portal for details. Haven't booked yet? You can search for Central United States adult-only hotels that allow full refunds — should you need one. Lock in your grown-up getaway with the assurance that wherever you choose to stay, you'll always be A-OK!