Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Charleston Independent Hotels

See all 2,095 Hotels in Charleston
The Meeting Street Inn

The Meeting Street Inn

173 Meeting Street, Charleston
3.5 out of 5.0
4.3 out of 5 (552 reviews)
Excellent Customer Service Parking is a few blocks away. Outdoor rooms, so fairly noisy. We heard a lot from the person above … - 

$125

$125
The Francis Marion Hotel

The Francis Marion Hotel

387 King St, Charleston
4.5 out of 5.0
4.2 out of 5 (2,225 reviews)
Last minute stay Booked thru Expedia at the last minute when we decided not to drive back to Murrels Inlet as it was … - 

$143

$143
The Indigo Inn

The Indigo Inn

1 Maiden lane, Charleston
3.0 out of 5.0
4.5 out of 5 (574 reviews)
Great location! My husband and I had a wonderful stay at the Indigo Inn. The staff was attentive and even let us ch … - 

$104

$104
King Charles Inn

King Charles Inn

237 Meeting Street, Charleston
4.0 out of 5.0
4.4 out of 5 (2,079 reviews)
Great location and nice common areas, will stay he We booked on-line and were pleasantly surprised by the property. It has on-site parking, a nice rec … - 

$119

$119
Town & Country Inn and Suites

Town & Country Inn and Suites

2008 Savannah Hwy, Charleston
3.5 out of 5.0
4.7 out of 5 (2,525 reviews)
Excellent stay. Great exercise room. Sounds trifling, but no fan in the bathroom. Bummer when sharing a room... - 

$89

$89
The Dewberry Charleston

The Dewberry Charleston

334 Meeting Street, Charleston
5.0 out of 5.0
4.8 out of 5 (186 reviews)
Excellent staff, wonderful food, beautiful rooms. Will be back. - 

$249

$249
Ansonborough Inn

Ansonborough Inn

21 Hasell Street, Charleston
3.5 out of 5.0
4.8 out of 5 (753 reviews)
Great location! We liked the hotel and staff very much. Our only complain is that it is extremely dark inside. Othe … - 

$148

$148
Tides Folly Beach Hotel

Tides Folly Beach Hotel

1 Center Street Highway 171, Folly Beach
3.5 out of 5.0
4.1 out of 5 (1,322 reviews)
Hotel is right on the beach Hotel is always one of my favorites. For off season, the services were fine and matched with the re … - 

$119

$119
Market Pavilion Hotel

Market Pavilion Hotel

225 East Bay Street, Charleston
4.5 out of 5.0
4.6 out of 5 (468 reviews)
Excellent location for shopping & dining. Wonderful staff and location. Great restaurant in the hotel or numerous other dining locations with … - 

$199

$199
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

20 Patriots Point Rd, Mount Pleasant
4.0 out of 5.0
4.1 out of 5 (2,069 reviews)
They could stand to get better pillows. Bathroom was small & the shower glass door should either co … - 

$119

$119
Seaside Inn Oceanfront

Seaside Inn Oceanfront

1004 Ocean Blvd, Isle Of Palms
2.5 out of 5.0
3.3 out of 5 (1,105 reviews)
Blissfully Serene The room fit our needs for a short stay! Had small fridge, microwave, coffee pot, and adequate show … - 

$73

$73
The Vendue

The Vendue

19 Vendue Range, Charleston
4.5 out of 5.0
4.5 out of 5 (1,153 reviews)
Nicest hotel room I’ve ever seen & great staff too - 

$159

$159
Andrew Pinckney Inn

Andrew Pinckney Inn

40 Pinckney St, Charleston
4.5 out of 5.0
4.3 out of 5 (1,048 reviews)
Great hotel with characters near everything It’s not overly lavish and pampering but very comfortable, just the right size to have some persona … - 

$139

$139
Barksdale House Inn

Barksdale House Inn

27 George Street, Charleston
3.0 out of 5.0
4.2 out of 5 (632 reviews)
Convenient in the middle of it all! A very affordable option conveniently located off King St. that is between the sites to south of th … - 

$119

$119
Fulton Lane Inn

Fulton Lane Inn

202 King St, Charleston
3.5 out of 5.0
4.5 out of 5 (608 reviews)
Staff was the shining star From check in to check out the staff was amazing. Location was excellent and the room was clean. Re … - 

$159

$159
North Charleston Inn

North Charleston Inn

2934 W Montague Ave, North Charleston
3.0 out of 5.0
2.9 out of 5 (1,401 reviews)
Nice Hotel Clean hotel but the heating system needs to be worked and fixed - 

$70

$70
The Spectator Hotel

The Spectator Hotel

67 State Street, Charleston
4.5 out of 5.0
4.9 out of 5 (155 reviews)
Great property The staff went above and beyond to get my mother from the hotel to the cruise ship during the worst … - 

$239

$239
Charleston Grand Hotel

Charleston Grand Hotel

3640 Dorchester Rd, North Charleston
3.0 out of 5.0
3.1 out of 5 (837 reviews)
Nice hotel for the price I really enjoyed my stay it wasn't expensive but it was clean and the staff was helpful the restaur … - 

$70

$70
French Quarter Inn

French Quarter Inn

166 Church St, Charleston
4.5 out of 5.0
4.9 out of 5 (830 reviews)
Great hotel in Charleston Great professional staff, very kind. A welcome glass of sparkling wine, a smile, cozy atmosphere et … - 

$209

$209
North Charleston Marriott

North Charleston Marriott

4770 Goer Dr, North Charleston
3.5 out of 5.0
3.7 out of 5 (1,060 reviews)
Spacious, modern, clean, bright. Staff very warm and friendly...quite service-oriented. Food option … - 

$98

$98
Map

Recently booked Charleston hotels

Hampton Inn & Suites Charleston Airport
2.5 out of 5.0
Last booking: 7 minutes ago
Zero George Street
4.5 out of 5.0
Last booking: 1 hour ago
The Francis Marion Hotel
4.5 out of 5.0
Last booking: 2 hours ago
The Inn At Middleton Place
3.0 out of 5.0
Last booking: 2 hours ago
The Restoration
4.0 out of 5.0
Last booking: 2 hours ago
Home2 Suites by Hilton Charleston Airport/Convention Center
3.0 out of 5.0
Last booking: 3 hours ago
HarbourView Inn
4.5 out of 5.0
Last booking: 3 hours ago
Springhill Suites by Marriott Charleston Mount Pleasant
3.0 out of 5.0
Last booking: 3 hours ago
The Indigo Inn
3.0 out of 5.0
Last booking: 3 hours ago

Independent Charleston Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Charleston, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Charleston hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Charleston Independent locations may even offer extra little benefits and discounts for frequent travelers.