Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Charleston Independent Hotels

See all 1,011 Hotels in Charleston
Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center

3234 W Montague Ave, North Charleston
3.0 out of 5.0
4.6 out of 5 (850 reviews)
Central location. Very comfortable and relaxing. Will definitely be staying here on future trips. - 

$107

$107
Motel 6 Charleston North SC

Motel 6 Charleston North SC

2551 Ashley Phosphate Rd, North Charleston
1.5 out of 5.0
3.0 out of 5 (399 reviews)
Close to downtown Good, but some clients are very load in the middle of the night - 

$56

$56
The Francis Marion Hotel

The Francis Marion Hotel

387 King St, Charleston
4.0 out of 5.0
4.2 out of 5 (3,076 reviews)
We were able to check in as soon as we arrived. The hotel lobby was a exactly as it was in the on l … - 

$134

$134
Holiday Inn Express Charleston Dwtn - Medical Area

Holiday Inn Express Charleston Dwtn - Medical Area

250 Spring Street, Charleston
3.0 out of 5.0
3.8 out of 5 (1,191 reviews)
Delightful Staff and Easy Access to VA & Hospitals Although the rooms are somewhat cramped and offer only a shower--no bathtub--there is great flexibi … - 

$90

$90
Aloft Charleston Airport & Convention Center

Aloft Charleston Airport & Convention Center

4875 Tanger Outlet Blvd, North Charleston
3.0 out of 5.0
3.8 out of 5 (1,038 reviews)
Modern Amenities Nice modern hotel. The food area was great late night. Bagels, muffins, plenty to drink, etc. Break … - 

$109

$109
King Charles Inn

King Charles Inn

237 Meeting Street, Charleston
3.5 out of 5.0
4.4 out of 5 (2,109 reviews)
Great location and friendly staff. Great location and within walking distance of all the sights. We were five hours early for check in … - 

$149

$149
Red Roof Inn North Charleston Coliseum

Red Roof Inn North Charleston Coliseum

7480 Northwoods Blvd, North Charleston
2.0 out of 5.0
3.4 out of 5 (1,047 reviews)
Comfortable, Clean, Friendly Staff We stayed at Red Roof North Charleston for two nights while we explored the Charleston area. We jus … - 

$67

$67
Hyatt Place Charleston/Historic District

Hyatt Place Charleston/Historic District

560 King Street, Charleston
3.0 out of 5.0
4.5 out of 5 (545 reviews)
Beautiful Hotel I loved this hotel. The front desk staff (Jordan) helped us with suggestions for dinner and they we … - 

$137

$137
Red Roof PLUS+ Mt Pleasant - Patriots Point

Red Roof PLUS+ Mt Pleasant - Patriots Point

301 Johnnie Dodds Blvd, Mount Pleasant
2.5 out of 5.0
3.7 out of 5 (1,794 reviews)
Decent Hotel Stay Hotel stay was acceptable. Staff at front desk were very friendly and helpful. Room was in need of … - 

$81

$81
Quality Inn & Suites

Quality Inn & Suites

2499 La Quinta Ln, North Charleston
2.5 out of 5.0
3.1 out of 5 (1,391 reviews)
Very quiet, comfortable. Was a pleasure to stay, I am willing to go back. So quiet, nice view, etc. - 

$52

$52
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

20 Patriots Point Rd, Mount Pleasant
3.5 out of 5.0
4.1 out of 5 (2,259 reviews)
Clean, friendly staff, great location This hotel is located water directly across from Charleston. Convenient to Charleston and other int … - 

$129

$129
Belmond Charleston Place

Belmond Charleston Place

205 Meeting Street, Charleston
5.0 out of 5.0
4.7 out of 5 (1,496 reviews)
Wonderful all around Great staff Great service Super comfortable beds and clean bathrooms - 

$299

$299
Hyatt Place North Charleston

Hyatt Place North Charleston

2455 Prospect Drive, North Charleston
3.0 out of 5.0
4.5 out of 5 (1,461 reviews)
Wonderful Helpful Staff!!! BEAUTIFUL LOBBY AND ROOMS.... - 

$91

$91
Town & Country Inn and Suites

Town & Country Inn and Suites

2008 Savannah Hwy, Charleston
3.0 out of 5.0
4.7 out of 5 (2,465 reviews)
I enjoyed my stay. It is a really nice hotel. Easy access tot he airport and really anywhere you ne … - 

$99

$99
The Dewberry Charleston

The Dewberry Charleston

334 Meeting Street, Charleston
5.0 out of 5.0
4.7 out of 5 (149 reviews)
GReat place to stay Had a wonderful stay at this great hotel. Staff couldn’t be nicer, rooms appointed well. In a good … - 

$249

$249
Market Pavilion Hotel

Market Pavilion Hotel

225 East Bay Street, Charleston
4.5 out of 5.0
4.6 out of 5 (444 reviews)
Beautiful Hotel in Excellent Location This charming old hotel captures the old culture of Charleston. The rooms are large and extremely w … - 

$209

$209
Wild Dunes Resort By Destination Hotels

Wild Dunes Resort By Destination Hotels

1 Sundial Circle, Isle of Palms
4.0 out of 5.0
4.4 out of 5 (1,812 reviews)
The room was great but... The rooms was great but the pools are not heated. This was a massive problem. - 

$135

$135
Wyndham Garden Summerville

Wyndham Garden Summerville

120 Holiday Inn Drive, Summerville
3.0 out of 5.0
3.9 out of 5 (125 reviews)
Nice updates The updates are very nice . The bed however was hard and pillows both pillows were feather which mi … - 

$93

$93
The Meeting Street Inn

The Meeting Street Inn

173 Meeting Street, Charleston
3.0 out of 5.0
4.3 out of 5 (487 reviews)
Pleasant surprise I was expecting a cute little inn, which it was, but this place definitely exceeded expectations! W … - 

$125

$125
Homewood Suites by Hilton Charleston Historic District

Homewood Suites by Hilton Charleston Historic District

415 Meeting Street, Charleston
3.0 out of 5.0
4.8 out of 5 (17 reviews)
Great Hotel This hotel is worth staying in. A modern and well designed hotel with very helpful staff. Great roo … - 

$118

$118
Map

Recently booked Charleston hotels

Days Inn Ladson Summerville Charleston
2.0 out of 5.0
Last booking: 3 minutes ago
Fairfield Inn & Suites Charleston North/University Area
2.5 out of 5.0
Last booking: 25 minutes ago
Hyatt Place North Charleston
3.0 out of 5.0
Last booking: 30 minutes ago
Hawthorn Suites by Wyndham Charleston
2.5 out of 5.0
Last booking: 34 minutes ago
Hawthorn Suites by Wyndham North Charleston, SC
3.0 out of 5.0
Last booking: 37 minutes ago
North Charleston Marriott
3.5 out of 5.0
Last booking: 41 minutes ago
La Quinta Inn Charleston North
2.5 out of 5.0
Last booking: 41 minutes ago
Home2 Suites by Hilton Charleston Airport/Convention Center
2.5 out of 5.0
Last booking: 42 minutes ago
Best Western Plus Airport Inn & Suites
2.5 out of 5.0
Last booking: 54 minutes ago

Independent Charleston Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Charleston, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Charleston hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Charleston Independent locations may even offer extra little benefits and discounts for frequent travelers.