Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Charleston Independent Hotels

See all 1,011 Hotels in Charleston
The Francis Marion Hotel

The Francis Marion Hotel

387 King St, Charleston
4.0 out of 5.0
4.2 out of 5 (3,077 reviews)
We were able to check in as soon as we arrived. The hotel lobby was a exactly as it was in the on l … - 

$134

$134
Aloft Charleston Airport & Convention Center

Aloft Charleston Airport & Convention Center

4875 Tanger Outlet Blvd, North Charleston
3.0 out of 5.0
3.8 out of 5 (1,041 reviews)
Modern Amenities Nice modern hotel. The food area was great late night. Bagels, muffins, plenty to drink, etc. Break … - 

$109

$109
Motel 6 Charleston North SC

Motel 6 Charleston North SC

2551 Ashley Phosphate Rd, North Charleston
1.5 out of 5.0
3.0 out of 5 (401 reviews)
Close to downtown Good, but some clients are very load in the middle of the night - 

$56

$56
Hyatt Place North Charleston

Hyatt Place North Charleston

2455 Prospect Drive, North Charleston
3.0 out of 5.0
4.5 out of 5 (1,465 reviews)
Great hotel near Charleston I thought an accessible room would have a walk-in shower but it had a tub. They switched me to a re … - 

$91

$91
Holiday Inn Express Charleston Dwtn - Medical Area

Holiday Inn Express Charleston Dwtn - Medical Area

250 Spring Street, Charleston
3.0 out of 5.0
3.8 out of 5 (1,199 reviews)
. Hotel review Breakfast was nice. Fairly close to downtown and they have transport taxi service that stations the … - 

$90

$90
Red Roof Inn North Charleston Coliseum

Red Roof Inn North Charleston Coliseum

7480 Northwoods Blvd, North Charleston
2.0 out of 5.0
3.4 out of 5 (1,048 reviews)
Comfortable, Clean, Friendly Staff We stayed at Red Roof North Charleston for two nights while we explored the Charleston area. We jus … - 

$67

$67
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

20 Patriots Point Rd, Mount Pleasant
3.5 out of 5.0
4.1 out of 5 (2,262 reviews)
Wonderful resort Extremely quiet and comfortable stay in lush setting. Shuttle provided to downtown. Within walking … - 

$119

$119
Hyatt Place Charleston/Historic District

Hyatt Place Charleston/Historic District

560 King Street, Charleston
3.0 out of 5.0
4.5 out of 5 (546 reviews)
Beautiful Hotel I loved this hotel. The front desk staff (Jordan) helped us with suggestions for dinner and they we … - 

$137

$137
Homewood Suites by Hilton Charleston Historic District

Homewood Suites by Hilton Charleston Historic District

415 Meeting Street, Charleston
3.0 out of 5.0
4.8 out of 5 (17 reviews)
Great Hotel This hotel is worth staying in. A modern and well designed hotel with very helpful staff. Great roo … - 

$118

$118
Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center

3234 W Montague Ave, North Charleston
3.0 out of 5.0
4.6 out of 5 (850 reviews)
Central location. Very comfortable and relaxing. Will definitely be staying here on future trips. - 

$107

$107
Hawthorn Suites by Wyndham Charleston

Hawthorn Suites by Wyndham Charleston

2455 Savannah Hwy, Charleston
2.5 out of 5.0
3.8 out of 5 (1,107 reviews)
Dirty areas Futures next to wall, carpet need cleaning. Bath room floor need more cleaning - 

$61

$61
The Meeting Street Inn

The Meeting Street Inn

173 Meeting Street, Charleston
3.0 out of 5.0
4.3 out of 5 (487 reviews)
Pleasant surprise I was expecting a cute little inn, which it was, but this place definitely exceeded expectations! W … - 

$125

$125
Quality Inn & Suites

Quality Inn & Suites

2499 La Quinta Ln, North Charleston
2.5 out of 5.0
3.1 out of 5 (1,391 reviews)
Very quiet, comfortable. Was a pleasure to stay, I am willing to go back. So quiet, nice view, etc. - 

$52

$52
Belmond Charleston Place

Belmond Charleston Place

205 Meeting Street, Charleston
5.0 out of 5.0
4.7 out of 5 (1,500 reviews)
Perfect location for shopping and eating Perfect location for shopping and eating I I would recommend this hotel to my friends and family - 

$299

$299
King Charles Inn

King Charles Inn

237 Meeting Street, Charleston
3.5 out of 5.0
4.4 out of 5 (2,110 reviews)
King Charles Inn This was our second stay at the King Charles. Great staff and comfortable room. There are stairs to … - 

$149

$149
Town & Country Inn and Suites

Town & Country Inn and Suites

2008 Savannah Hwy, Charleston
3.0 out of 5.0
4.7 out of 5 (2,471 reviews)
Great stay. Check in was fast. The room was clean and beautiful. Comfy chairs and very comfy bed. I would defin … - 

$99

$99
Wyndham Garden Summerville

Wyndham Garden Summerville

120 Holiday Inn Drive, Summerville
3.0 out of 5.0
3.9 out of 5 (126 reviews)
Nice updates The updates are very nice . The bed however was hard and pillows both pillows were feather which mi … - 

$97

$97
Red Roof PLUS+ Mt Pleasant - Patriots Point

Red Roof PLUS+ Mt Pleasant - Patriots Point

301 Johnnie Dodds Blvd, Mount Pleasant
2.5 out of 5.0
3.7 out of 5 (1,796 reviews)
Close to Charleston Nice staff. Comfortable room. Did not upgrade so no fridge or microwave. Safe did not work. Very co … - 

$81

$81
The Dewberry Charleston

The Dewberry Charleston

334 Meeting Street, Charleston
5.0 out of 5.0
4.7 out of 5 (151 reviews)
Charleston Hidden Gem Well at least I’d never heard of it and I’ve been there 20+ times. 5 star Hotel in my mind. - 

$249

$249
Extended Stay America - Charleston - North Charleston

Extended Stay America - Charleston - North Charleston

5059 N Arco Ln, North Charleston
2.0 out of 5.0
2.8 out of 5 (415 reviews)
staff The manager Sarah and the young lady at the desk were outstanding. They went above and beyond their … - 

$67

$67
Map

Recently booked Charleston hotels

Days Inn Historic District
2.0 out of 5.0
Last booking: 4 hours ago
Comfort Inn Downtown Charleston
2.5 out of 5.0
Last booking: 4 hours ago
Country Inn & Suites By Carlson, Charleston North, SC
2.5 out of 5.0
Last booking: 4 hours ago
Best Western Plus Airport Inn & Suites
2.5 out of 5.0
Last booking: 5 hours ago
Hampton Inn Charleston - Historic District
2.5 out of 5.0
Last booking: 5 hours ago
The Meeting Street Inn
3.0 out of 5.0
Last booking: 5 hours ago
The Francis Marion Hotel
4.0 out of 5.0
Last booking: 5 hours ago
Value Place Charleston, SC (Northside)
2.5 out of 5.0
Last booking: 6 hours ago
Motel 6 Charleston North SC
1.5 out of 5.0
Last booking: 7 hours ago

Independent Charleston Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Charleston, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Charleston hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Charleston Independent locations may even offer extra little benefits and discounts for frequent travelers.