Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Charleston Independent Hotels

See all 2,020 Hotels in Charleston
The Francis Marion Hotel

The Francis Marion Hotel

387 King St, Charleston
4.0 out of 5.0
4.2 out of 5 (2,221 reviews)
Beautiful hotel. Great location. For the money, hotel seemed overpriced. Bathrooms were tiny. AC was loud. Almost every time I was i … - 
The Meeting Street Inn

The Meeting Street Inn

173 Meeting Street, Charleston
3.0 out of 5.0
4.3 out of 5 (587 reviews)
Nice hotel in prime downtown location Beautiful older southern hotel with lots of charm. Close to straw Market and shops as well as sever … - 

$143

$143
Town & Country Inn and Suites

Town & Country Inn and Suites

2008 Savannah Hwy, Charleston
3.0 out of 5.0
4.7 out of 5 (2,555 reviews)
Charleston trip Great price close to downtown and other sites. Very nice rooms and clean with good staff. - 

$99

$99
The Indigo Inn

The Indigo Inn

1 Maiden lane, Charleston
2.5 out of 5.0
4.5 out of 5 (607 reviews)
Nice hotel, easy walk to everything. Could walk to everything. Not the neighborhood you would drive around. No place to park. But hotel … - 
Ansonborough Inn

Ansonborough Inn

21 Hasell Street, Charleston
3.0 out of 5.0
4.8 out of 5 (779 reviews)
Charming inn in the historic district. We loved this inn. Charming inside and out! Beautiful and comfortable room. The staff were friendly … - 

$160

$160
King Charles Inn

King Charles Inn

237 Meeting Street, Charleston
4.0 out of 5.0
4.4 out of 5 (2,079 reviews)
LOVELY Great location, very friendly staff and FREE parking. Need I say more? - 
Tides Folly Beach Hotel

Tides Folly Beach Hotel

1 Center Street Highway 171, Folly Beach
3.0 out of 5.0
4.1 out of 5 (1,334 reviews)
Great beach stay Tides is a very nice hotel and has the perfect location for those who just want to relax on the bea … - 

$119

$119
The Dewberry Charleston

The Dewberry Charleston

334 Meeting Street, Charleston
5.0 out of 5.0
4.8 out of 5 (200 reviews)
Fantastic Hotel! Located by some Beautiful houses. The hotel has everything that you might need. Curtous car to umbrellas. Fantastic place to stay. - 
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

20 Patriots Point Rd, Mount Pleasant
4.0 out of 5.0
4.1 out of 5 (2,095 reviews)
Room heat never worked Mthe room temperature never got above 62 degrees, even though it was set at 75. Nice place otherwis … - 

$119

$119
The Vendue

The Vendue

19 Vendue Range, Charleston
4.5 out of 5.0
4.5 out of 5 (1,163 reviews)
Perfect location to everything! We were lucky enough to stay a week in Charleston. The 1st room we were in had was tiny, had no win … - 
French Quarter Inn

French Quarter Inn

166 Church St, Charleston
4.0 out of 5.0
4.9 out of 5 (843 reviews)
Beautiful hotel. Service is top notch, lots of extras like bicycles, afternoon wine, breakfast, etc … - 

$249

$249
Seaside Inn Oceanfront

Seaside Inn Oceanfront

1004 Ocean Blvd, Isle Of Palms
3.3 out of 5 (1,118 reviews)
Staff is expedient. Room is clean. Smelled a little too much of cleaning products. - 
Market Pavilion Hotel

Market Pavilion Hotel

225 East Bay Street, Charleston
5.0 out of 5.0
4.6 out of 5 (482 reviews)
PERFECT. Incredibly attentive staff and a beautiful setting, we’ll definitely be back! - 
Andrew Pinckney Inn

Andrew Pinckney Inn

40 Pinckney St, Charleston
4.5 out of 5.0
4.3 out of 5 (1,052 reviews)
Great hotel with characters near everything It’s not overly lavish and pampering but very comfortable, just the right size to have some persona … - 
North Charleston Marriott

North Charleston Marriott

4770 Goer Dr, North Charleston
3.5 out of 5.0
3.7 out of 5 (1,063 reviews)
Please Read My Review The entire staff was absolutely excellent and obviously are focused on customer satisfaction. From … - 
HarbourView Inn

HarbourView Inn

2 Vendue Range, Charleston
4.5 out of 5.0
4.7 out of 5 (954 reviews)
Great hotel on the water We love this hotel and stay here when we can. This trip was for my birthday and, of course, the hot … - 
The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina

28 Patriots Point Road, Mount Pleasant
5.0 out of 5.0
4.7 out of 5 (128 reviews)
Incredibly comfortable experience. The rooms are gorgeous. - 

$197

$197
The Restoration

The Restoration

75 Wentworth Street, Charleston
4.5 out of 5.0
4.9 out of 5 (295 reviews)
Excellent Choice in Charleston This is the first time we have stayed at The Restoration in our many visits to Charleston. Our room … - 
Charleston Grand Hotel

Charleston Grand Hotel

3640 Dorchester Rd, North Charleston
3.0 out of 5.0
3.1 out of 5 (845 reviews)
it was satisfactory room was clean had no issues with anything staff was friendly and polite everything was good - 
North Charleston Inn

North Charleston Inn

2934 W Montague Ave, North Charleston
3.0 out of 5.0
2.9 out of 5 (1,411 reviews)
Just here overnight arrived late. Very inviting court yard with pool. - 

Recently booked Charleston hotels

SpringHill Suites by Marriott Charleston Downtown Riverview
0.0 out of 5.0
Last booking: 6 minutes ago
The Francis Marion Hotel
4.0 out of 5.0
Last booking: 9 minutes ago
Comfort Inn Downtown Charleston
3.0 out of 5.0
Last booking: 16 minutes ago
North Charleston Inn
3.0 out of 5.0
Last booking: 17 minutes ago
Wild Dunes Resort By Destination Hotels
4.5 out of 5.0
Last booking: 21 minutes ago
Wingate by Wyndham Charleston Airport Coliseum
2.5 out of 5.0
Last booking: 22 minutes ago
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17
3.0 out of 5.0
Last booking: 24 minutes ago
Comfort Inn & Suites Convention Center
2.5 out of 5.0
Last booking: 26 minutes ago
The Mills House Wyndham Grand Hotel
4.0 out of 5.0
Last booking: 38 minutes ago

Independent Charleston Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Charleston, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Charleston hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Charleston Independent locations may even offer extra little benefits and discounts for frequent travelers.