Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Charleston Independent Hotels

See all 1,011 Hotels in Charleston
The Francis Marion Hotel

The Francis Marion Hotel

387 King St, Charleston
4.0 out of 5.0
4.2 out of 5 (3,077 reviews)
We were able to check in as soon as we arrived. The hotel lobby was a exactly as it was in the on l … - 

$134

$134
Aloft Charleston Airport & Convention Center

Aloft Charleston Airport & Convention Center

4875 Tanger Outlet Blvd, North Charleston
3.0 out of 5.0
3.8 out of 5 (1,040 reviews)
Modern Amenities Nice modern hotel. The food area was great late night. Bagels, muffins, plenty to drink, etc. Break … - 

$109

$109
Motel 6 Charleston North SC

Motel 6 Charleston North SC

2551 Ashley Phosphate Rd, North Charleston
1.5 out of 5.0
3.0 out of 5 (400 reviews)
Close to downtown Good, but some clients are very load in the middle of the night - 

$56

$56
Hyatt Place North Charleston

Hyatt Place North Charleston

2455 Prospect Drive, North Charleston
3.0 out of 5.0
4.5 out of 5 (1,463 reviews)
Great. Comfortable hotel. Clean, neat, warm, good breakfast, nice staff, lots of close parking - 

$91

$91
Holiday Inn Express Charleston Dwtn - Medical Area

Holiday Inn Express Charleston Dwtn - Medical Area

250 Spring Street, Charleston
3.0 out of 5.0
3.8 out of 5 (1,197 reviews)
Decent Hotel for the money The staff were professional, friendly, and knowledgeable. The hot breakfast was good. They had scra … - 

$90

$90
Red Roof Inn North Charleston Coliseum

Red Roof Inn North Charleston Coliseum

7480 Northwoods Blvd, North Charleston
2.0 out of 5.0
3.4 out of 5 (1,048 reviews)
Comfortable, Clean, Friendly Staff We stayed at Red Roof North Charleston for two nights while we explored the Charleston area. We jus … - 

$67

$67
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

20 Patriots Point Rd, Mount Pleasant
3.5 out of 5.0
4.1 out of 5 (2,261 reviews)
Wonderful resort Extremely quiet and comfortable stay in lush setting. Shuttle provided to downtown. Within walking … - 

$129

$129
Hyatt Place Charleston/Historic District

Hyatt Place Charleston/Historic District

560 King Street, Charleston
3.0 out of 5.0
4.5 out of 5 (546 reviews)
Beautiful Hotel I loved this hotel. The front desk staff (Jordan) helped us with suggestions for dinner and they we … - 

$137

$137
Homewood Suites by Hilton Charleston Historic District

Homewood Suites by Hilton Charleston Historic District

415 Meeting Street, Charleston
3.0 out of 5.0
4.8 out of 5 (17 reviews)
Great Hotel This hotel is worth staying in. A modern and well designed hotel with very helpful staff. Great roo … - 

$118

$118
Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center

3234 W Montague Ave, North Charleston
3.0 out of 5.0
4.6 out of 5 (850 reviews)
Central location. Very comfortable and relaxing. Will definitely be staying here on future trips. - 

$107

$107
Hawthorn Suites by Wyndham Charleston

Hawthorn Suites by Wyndham Charleston

2455 Savannah Hwy, Charleston
2.5 out of 5.0
3.8 out of 5 (1,105 reviews)
Great location Hotel rooms are spacious, clean and the staff are helpful. The hotel is less than 30 minutes from D … - 

$61

$61
The Meeting Street Inn

The Meeting Street Inn

173 Meeting Street, Charleston
3.0 out of 5.0
4.3 out of 5 (487 reviews)
Pleasant surprise I was expecting a cute little inn, which it was, but this place definitely exceeded expectations! W … - 

$125

$125
Quality Inn & Suites

Quality Inn & Suites

2499 La Quinta Ln, North Charleston
2.5 out of 5.0
3.1 out of 5 (1,391 reviews)
Very quiet, comfortable. Was a pleasure to stay, I am willing to go back. So quiet, nice view, etc. - 

$52

$52
Belmond Charleston Place

Belmond Charleston Place

205 Meeting Street, Charleston
5.0 out of 5.0
4.7 out of 5 (1,498 reviews)
Wonderful all around Great staff Great service Super comfortable beds and clean bathrooms - 

$299

$299
King Charles Inn

King Charles Inn

237 Meeting Street, Charleston
3.5 out of 5.0
4.4 out of 5 (2,110 reviews)
King Charles Inn This was our second stay at the King Charles. Great staff and comfortable room. There are stairs to … - 

$149

$149
Town & Country Inn and Suites

Town & Country Inn and Suites

2008 Savannah Hwy, Charleston
3.0 out of 5.0
4.7 out of 5 (2,470 reviews)
Love this hotel! Clean, quiet, comfortable, close to everywhere you need to go. I will stay here ev … - 

$99

$99
Wyndham Garden Summerville

Wyndham Garden Summerville

120 Holiday Inn Drive, Summerville
3.0 out of 5.0
3.9 out of 5 (126 reviews)
Nice updates The updates are very nice . The bed however was hard and pillows both pillows were feather which mi … - 

$93

$93
Red Roof PLUS+ Mt Pleasant - Patriots Point

Red Roof PLUS+ Mt Pleasant - Patriots Point

301 Johnnie Dodds Blvd, Mount Pleasant
2.5 out of 5.0
3.7 out of 5 (1,795 reviews)
Close to Charleston Nice staff. Comfortable room. Did not upgrade so no fridge or microwave. Safe did not work. Very co … - 

$81

$81
The Dewberry Charleston

The Dewberry Charleston

334 Meeting Street, Charleston
5.0 out of 5.0
4.7 out of 5 (150 reviews)
Charleston Hidden Gem Well at least I’d never heard of it and I’ve been there 20+ times. 5 star Hotel in my mind. - 

$249

$249
Extended Stay America - Charleston - North Charleston

Extended Stay America - Charleston - North Charleston

5059 N Arco Ln, North Charleston
2.0 out of 5.0
2.8 out of 5 (415 reviews)
staff The manager Sarah and the young lady at the desk were outstanding. They went above and beyond their … - 

$67

$67
Map

Recently booked Charleston hotels

Days Inn Historic District
2.0 out of 5.0
Last booking: 5 minutes ago
Sleep Inn Mt. Pleasant - Charleston
2.0 out of 5.0
Last booking: 17 minutes ago
The Meeting Street Inn
3.0 out of 5.0
Last booking: 23 minutes ago
The Mills House Wyndham Grand Hotel
4.0 out of 5.0
Last booking: 28 minutes ago
Value Place Charleston, SC (Central)
2.5 out of 5.0
Last booking: 50 minutes ago
The Spectator Hotel
4.0 out of 5.0
Last booking: 50 minutes ago
Seaside Inn Oceanfront
2.5 out of 5.0
Last booking: 53 minutes ago
SpringHill Suites by Marriott Charleston N./Ashley Phosphate
3.0 out of 5.0
Last booking: 53 minutes ago
Wild Dunes Resort By Destination Hotels
4.0 out of 5.0
Last booking: 1 hour ago

Independent Charleston Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Charleston, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Charleston hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Charleston Independent locations may even offer extra little benefits and discounts for frequent travelers.