Title: $105 Cheap Flights to Florence Regional, SC - Expedia.com ![Wyche Pavilion Greenville South Carolina ](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1221/22638cec-95e4-4f53-af15-3963f8a47f19.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # $105 Cheap Flights to Florence Regional, SC [View $105 flight on Wed, Mar 4, 2026](https://expedia.com/Flights-Search?trip=oneway&leg1=from:IAD,to:FLO,departure:3/4/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:104.20&airProductToken=AQpoCjIIwYIBEgQ1MTAwGIgYIOKaASj-3YYDMOLehgM4QkAAWAFqBUJBU0lDcghPVkFYWk5CVgoyCMGCARIENTk4MxjimgEg5XIom-CGAzDd4IYDOEJAAVgBagVCQVNJQ3IIT1ZBWFpOQlYSDAgBEAEYASoCQUEyABgBIgQIARABKAIoAygEMAs) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travelers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Flight 1 Leaving from Going to Departing Flight 2 Leaving from Going to Departing ## Popular airlines to Florence, SC (FLO-Florence Regional) - ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:FLO,departure:2/28/2026TANYT&leg2=from:FLO,to:CMH,departure:3/7/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our OneKeyCash [Learn about One Key](https://www.expedia.com/welcome-one-key) ## How much is the cheapest flight to Florence Regional? Prices were available within the past 7 days and start at $105 for one-way flights and $209 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Apr 25 - Sat, May 2 DCA Washington FLO Florence $209 Roundtrip found 9 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DCA,to:FLO,departure:4/25/2026TANYT&leg2=from:FLO,to:DCA,departure:5/2/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:208.40&airProductToken=AQpnCjEIwYIBEgQzMjQwGEMg4poBKLKqiwMwnquLAzhCQABYAWoFQkFTSUNyCE9WRldaTkJWCjIIwYIBEgQ1ODkzGOKaASDlcijlq4sDMKmsiwM4QkABWAFqBUJBU0lDcghPVkZXWk5CVgpnCjIIwYIBEgQ2MDAzGOVyIOKaASjA94sDMIX4iwM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoxCMGCARIEMTM1NBjimgEgQyjM-YsDMKf6iwM4QkABWAFqBUJBU0lDcghPVkZXWk5CVhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, Mar 10 - Wed, Mar 18 IAD Washington FLO Florence $209 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:IAD,to:FLO,departure:3/10/2026TANYT&leg2=from:FLO,to:IAD,departure:3/18/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:208.40&airProductToken=AQpoCjIIwYIBEgQ1MjAzGIgYIOKaASiCoYcDMOahhwM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoyCMGCARIENTk4MxjimgEg5XIon6OHAzDho4cDOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYKaAoyCMGCARIENTgzOBjlciDimgEojPiHAzDP-IcDOEJAAFgBagVCQVNJQ3IIT1ZGV1pOQlYKMgjBggESBDUxOTQY4poBIIgYKIP5hwMw4PmHAzhCQAFYAWoFQkFTSUNyCE9WRldaTkJWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Wed, May 13 - Wed, May 27 JFK New York FLO Florence $229 Roundtrip found 1 day ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:JFK,to:FLO,departure:5/13/2026TANYT&leg2=from:FLO,to:JFK,departure:5/27/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:228.40&airProductToken=AQpoCjIIwYIBEgQzMTY3GKlRIOKaASjh9IwDMPD1jAM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoyCMGCARIENTg5MxjimgEg5XIopfaMAzDp9owDOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYKZwoyCMGCARIENjAwNBjlciDimgEoxYuOAzCEjI4DOEJAAFgBagVCQVNJQ3IIT1ZGV1pOQlYKMQjBggESAzM3NBjimgEgqVEox42OAzDBjo4DOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Mar 7 - Sat, Mar 14 EWR New York FLO Florence $229 Roundtrip found 14 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:EWR,to:FLO,departure:3/7/2026TANYT&leg2=from:FLO,to:EWR,departure:3/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:228.40&airProductToken=AQppCjMIwYIBEgQxMzMwGMSNASDimgEovoOHAzDAhIcDOEJAAFgBagVCQVNJQ3IIT1ZGV1pOQlYKMgjBggESBDU4OTMY4poBIOVyKIqFhwMwyYWHAzhCQAFYAWoFQkFTSUNyCE9WRldaTkJWCmkKMgjBggESBDU4MzgY5XIg4poBKIzLhwMwz8uHAzhCQABYAWoFQkFTSUNyCE9WRldaTkJWCjMIwYIBEgQxNzA3GOKaASDEjQEom8yHAzCPzYcDOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Mar 7 - Sat, Mar 14 LGA New York FLO Florence $229 Roundtrip found 12 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:LGA,to:FLO,departure:3/7/2026TANYT&leg2=from:FLO,to:LGA,departure:3/14/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:228.40&airProductToken=AQpoCjIIwYIBEgQxMDg0GMsBIOKaASi1gocDMLiDhwM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoyCMGCARIENTg5MxjimgEg5XIoioWHAzDJhYcDOEJAAVgBagVCQVNJQ3IIT1ZGV1pOQlYKaAoyCMGCARIENTgzOBjlciDimgEojMuHAzDPy4cDOEJAAFgBagVCQVNJQ3IIT1ZGV1pOQlYKMgjBggESBDExODYY4poBIMsBKOnMhwMw182HAzhCQAFYAWoFQkFTSUNyCE9WRldaTkJWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ## Alternative airports near Florence Prices were available within the past 7 days. Prices and availability are subject to change. [](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:FLO,departure:2/28/2026TANYT&leg2=from:FLO,to:CMH,departure:3/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) FLO Florence Regional CheapestClosest 5 min [Flights from $540 ](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:FLO,departure:2/28/2026TANYT&leg2=from:FLO,to:CMH,departure:3/1/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=FTG_SPRING_PROMO_) ## Tips to find the cheapest flights to Florence Regional **The cheapest day to fly** Get started finding a cheap flight to Florence Regional on Expedia by either choosing a deal on this page or entering into the search bar your travel dates, origin airport, and whether you want roundtrip or one-way airfare. You can filter for flexibility, number of stops, airline, and departure/arrival times to find the best flight for you. **The cheapest month to fly** April is the cheapest month to fly to Florence Regional. This coincides with the low season when fewer people travel. Whichever month you travel in, though, be sure to book at least a month in advance if you want to score cheap tickets to Florence Regional. ARC's data shows that domestic flights booked 28 days or more before departure are typically 24% cheaper than those booked last minute. **The most affordable time to book a flight** Typically, a Sunday can be the cheapest time to book a flight to Florence Regional, according to ARC’s data. On average, you could save between 6% and 13% by booking on a Sunday instead of a Friday, which is the most expensive day to make a reservation. **The cheapest round-trip tickets to Florence Regional** The lowest price for round-trip flights to Florence Regional in 2026 starts from from $209, while one-way tickets start from from $105\. Expedia's effective search tool is one of the best ways to find a budget airfare. Simply enter your dates, and within seconds, it'll show you a vast selection of the cheapest flights to Florence Regional. If you have a preferred departure time or airline, you can use the handy filters to customize your search. **The cheapest airlines flying to Florence Regional** American Airlines are just some of the airlines that can typically offer cheap tickets to Florence Regional. You can find their most affordable flights by using the “airline” search filter and then sorting prices from low to high. As a trusted partner of the world's leading airlines, Expedia offers you some of the best airfare deals to Florence Regional and countless more destinations worldwide. **The most affordable airports to fly into** To view the cheapest airports to fly into for Florence Regional, simply order your search results from lowest to highest price. Expedia's search tool compares flight prices for all airports close to your destination, so you don't have to manually search them one by one to find the cheapest flight to Florence Regional. If you have a preferred place to fly into, take advantage of the “arrival airport” filter to narrow down your search on Expedia. **Save with a package** With Expedia's amazing [package deals](https://www.expedia.com/package-deals), you could save hundreds of dollars by booking your Florence Regional plane tickets together with your accommodations, car rental, or activities. Just select the search wizard's “package” option to view some of the cheapest deals. Look out for the green savings label to see how much you're saving. **Date flexibility for the cheapest flights to Florence Regional** If you can be flexible with your travel dates, it's a good idea to broaden your search by comparing prices on different days. This will open up more options, meaning you could uncover a less expensive flight to Florence Regional. **Stopover savings** The cheapest tickets to Florence Regional are sometimes those with a stopover. Book one of these flights, and you'll change planes at an airport en route to Florence Regional. While the overall travel time might be longer than a non-stop flight, you may decide it's worth it for the money saved. **Get Expedia's Price Drop Protection** Price Drop Protection means that if your flight gets cheaper after booking, you'll be credited the difference\*. This gives you peace of mind that you're getting one of the cheapest flights to Florence Regional for your chosen departure. Expedia's Price Drop Protection is available for a small fee but is free to One Key Gold and Platinum tier members. \*Terms apply. **Use our Price Tracking feature** Expedia's Price Tracking feature is another great tool that removes the guesswork from finding cheap flights to Florence Regional. Simply download the free Expedia app to your smart device and activate Florence Regional flight price alerts for your travel dates. There's even a price predictor tool that uses historical data to indicate the best time to book, giving you peace of mind that you'll nab the lowest prices. **Book with Expedia** As well as Price Drop Protection and Price Tracking, Expedia's close partnership with a vast selection of the world's leading airlines means you're sure to find cheap flights to Florence Regional. Plus, the One Key rewards program lets you earn real cash rewards on most bookings that you can use to save money on future trips. Best of all, it's free to join, and members often unlock exclusive discounts, too. Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages. \*Flight schedules are subject to change. __Flights to Florence Regional information__ | Destination airport | Florence Regional | | ----------------------------- | ----------------- | | Destination airport IATA code | FLO | | Destination city name | Florence | | Airlines serving | American Airlines | | Roundtrip price | $228 | | Popular airline | American Airlines | ## Trending flights to Florence Regional Prices were available within the past 7 days and start at $105 for one-way flights and $209 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Apr 25 - Sat, May 2 DCA Washington FLO Florence $209 Roundtrip found 9 hours ago [](https://expedia.com/Flights-Search?trip=roundtrip&leg1=from:DCA,to:FLO,departure:4/25/2026TANYT&leg2=from:FLO,to:DCA,departure:5/2/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:208.40&airProductToken=AQpnCjEIwYIBEgQzMjQwGEMg4poBKLKqiwMwnquLAzhCQABYAWoFQkFTSUNyCE9WRldaTkJWCjIIwYIBEgQ1ODkzGOKaASDlcijlq4sDMKmsiwM4QkABWAFqBUJBU0lDcghPVkZXWk5CVgpnCjIIwYIBEgQ2MDAzGOVyIOKaASjA94sDMIX4iwM4QkAAWAFqBUJBU0lDcghPVkZXWk5CVgoxCMGCARIEMTM1NBjimgEgQyjM-YsDMKf6iwM4QkABWAFqBUJBU0lDcghPVkZXWk5CVhIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Florence Hotels ](https://www.expedia.com/Florence-Hotels.d1221.Travel-Guide-Hotels) - [Hotels near Florence National Cemetery ](https://www.expedia.com/Florence-National-Cemetery-Hotels.0-l553248621532657341-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Station ](https://www.expedia.com/Florence-Station-Hotels.d6195493.Travel-Guide-Hotels) - [Hotels near Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Cheap-Hotels.0-0-d1221-tCheapHotels.Travel-Guide-Filter-Hotels) - [Pet-friendly Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Pet-Friendly-Hotel.0-0-d1221-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Luxury Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Luxury-Hotel.0-0-d1221-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Motels in Florence ](https://www.expedia.com/Florence-Motels.d1221-aaMotels.Travel-Guide-Accommodation) - [Hotels with an Indoor Pool in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Indoor-Pool.0-0-d1221-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Florence ](https://www.expedia.com/Florence-Hotels-Marriott-Hotels-Resorts.0-0-d1221--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Florence ](https://www.expedia.com/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Red Roof Inn Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Red-Roof-Inn.0-0-d1221--bRedRoofInn.Travel-Guide-Filter-Hotels) - [Hotels with Restaurants in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Restaurants.0-0-d1221-tHotelswithRestaurants.Travel-Guide-Filter-Hotels) - [Hotels with Bars in Florence ](https://www.expedia.com/Florence-Hotels-Bar-Hotel.0-0-d1221-tBarHotel.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Florence ](https://www.expedia.com/Florence-Cabins.d1221-aaCabins.Travel-Guide-Accommodation) - [Boutique Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Boutique-Hotel.0-0-d1221-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [B&B in Florence ](https://www.expedia.com/Florence-Bed-And-Breakfast.d1221-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Hotels with smoking rooms in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Smoking-Rooms.0-0-d1221-tHotelswithsmokingrooms.Travel-Guide-Filter-Hotels) - [Hotels with Connecting Rooms in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Adjoining-Rooms.0-0-d1221-tHotelswithAdjoiningRooms.Travel-Guide-Filter-Hotels) - [Hotels with Hot Tubs in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Hot-Tubs.0-0-d1221-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Florence ](https://www.expedia.com/4Star-Florence-Hotels.s40-0-d1221.Travel-Guide-Filter-Hotels) - [Apartments in Florence ](https://www.expedia.com/Florence-Apartments.d1221-aaApartments.Travel-Guide-Accommodation) - [Hotels with Balconies in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Balconies.0-0-d1221-tHotelswithBalconies.Travel-Guide-Filter-Hotels) - [Resorts & Hotels with Spas in Florence ](https://www.expedia.com/Florence-Hotels-Spa-Hotel.0-0-d1221-tSpaHotel.Travel-Guide-Filter-Hotels) - [Extended Stay Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Extended-Stay-Hotels.0-0-d1221-tExtendedStayHotels.Travel-Guide-Filter-Hotels) - [Romantic Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Romantic-Hotel.0-0-d1221-tRomanticHotel.Travel-Guide-Filter-Hotels) - [Historic Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Historic-Hotel.0-0-d1221-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Hotels with Room Service in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Room-Service.0-0-d1221-tHotelswithRoomService.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Wyndham-Hotels.0-0-d1221--bWyndhamHotels.Travel-Guide-Filter-Hotels) - [Golf Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Golf-Hotel.0-0-d1221-tGolfHotel.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Florence ](https://www.expedia.com/3Star-Florence-Hotels.s30-0-d1221.Travel-Guide-Filter-Hotels) - [Family Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Family-Hotel.0-0-d1221-tFamilyHotel.Travel-Guide-Filter-Hotels) - [Hotels with a Pool in Florence ](https://www.expedia.com/Florence-Hotels-Hotel-With-Pool.0-0-d1221-tHotelwithPool.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Kitchens.0-0-d1221-tHotelswithKitchens.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Wedding-Hotels.0-0-d1221-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Breakfast in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Complimentary-Breakfast.0-0-d1221-tHotelswithComplimentaryBreakfast.Travel-Guide-Filter-Hotels) - [Hotels with an Outdoor Pool in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Outdoor-Pool.0-0-d1221-tHotelswithOutdoorPool.Travel-Guide-Filter-Hotels) - [Hotels with a Gym in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Fitness-Center.0-0-d1221-tHotelswithFitnessCenter.Travel-Guide-Filter-Hotels) - [Honeymoon Resorts & in Florence ](https://www.expedia.com/Florence-Hotels-Honeymoon-Hotels.0-0-d1221-tHoneymoonHotels.Travel-Guide-Filter-Hotels) - [Best Western Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Best-Western.0-0-d1221--bBestWestern.Travel-Guide-Filter-Hotels) - [Guest Houses in Florence ](https://www.expedia.com/Florence-Guest-Houses.d1221-aaGuestHouses.Travel-Guide-Accommodation) - [Hotels with Suites in Florence ](https://www.expedia.com/Florence-Hotels-Hotel-Suites.0-0-d1221-tHotelSuites.Travel-Guide-Filter-Hotels) - [Hotels with Laundry Facilities in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Laundry-Facilities.0-0-d1221-tHotelswithLaundryFacilities.Travel-Guide-Filter-Hotels) - [Condo Rentals in Florence ](https://www.expedia.com/Florence-Condos.d1221-aaCondos.Travel-Guide-Accommodation) - [Beach Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Beach-Hotel.0-0-d1221-tBeachHotel.Travel-Guide-Filter-Hotels) - [Non-Smoking Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Smoke-Free-Hotels.0-0-d1221-tSmokeFreeHotels.Travel-Guide-Filter-Hotels) - [Hotels with Fireplaces in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Fireplaces.0-0-d1221-tHotelswithFireplaces.Travel-Guide-Filter-Hotels) - [Hotels & Resorts for Couples in Florence ](https://www.expedia.com/Florence-Hotels-Couples-Resorts-Hotels.0-0-d1221-tCouplesResortsHotels.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in Florence ](https://www.expedia.com/Florence-Hotels-LGBT-Welcoming-Hotel.0-0-d1221-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Vacation Homes in Florence ](https://www.expedia.com/Florence-Private-Vacation-Homes.d1221-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Hotels with Air Conditioning in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Air-Conditioning.0-0-d1221-tHotelswithAirConditioning.Travel-Guide-Filter-Hotels) - [Hotel with a Concierge Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Hotel-With-A-Concierge.0-0-d1221-tHotelwithaConcierge.Travel-Guide-Filter-Hotels) - [Business Hotels in Florence ](https://www.expedia.com/Florence-Hotels-Business-Hotel.0-0-d1221-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Hotels with Tennis Courts in Florence ](https://www.expedia.com/Florence-Hotels-Hotels-With-Tennis-Courts.0-0-d1221-tHotelswithTennisCourts.Travel-Guide-Filter-Hotels) - [Quinby Hotels ](https://www.expedia.com/Quinby-Hotels.d553248634998841600.Travel-Guide-Hotels) - [Hotels near Florence Museum ](https://www.expedia.com/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) - [Hotels near Francis Marion University ](https://www.expedia.com/Francis-Marion-University-Hotels.0-l6162133-0.Travel-Guide-Filter-Hotels) - [Hotels near Eastern Carolina Agricultural Fairgrounds ](https://www.expedia.com/Eastern-Carolina-Agricultural-Fairgrounds-Hotels.0-l6162140-0.Travel-Guide-Filter-Hotels) - [Hotels near Columns Plantation ](https://www.expedia.com/Columns-Plantation-Hotels.0-l553248621532657342-0.Travel-Guide-Filter-Hotels) - [Hotels near Magnolia Mall ](https://www.expedia.com/Magnolia-Mall-Hotels.0-l6165602-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Veterans Park ](https://www.expedia.com/Florence-Veterans-Park-Hotels.0-l619470572411232256-0.Travel-Guide-Filter-Hotels) - [Hotels near Florence Civic Center ](https://www.expedia.com/Florence-Civic-Center-Hotels.0-l6165605-0.Travel-Guide-Filter-Hotels) - [Hotels near Beaver Creek Golf Club ](https://www.expedia.com/Beaver-Creek-Golf-Club-Hotels.0-l553248621532657336-0.Travel-Guide-Filter-Hotels) - [Hotels near Palmetto Shores Lake ](https://www.expedia.com/Palmetto-Shores-Lake-Hotels.0-l553248635976195800-0.Travel-Guide-Filter-Hotels) - [Hotels near Oakdale Country Club ](https://www.expedia.com/Oakdale-Country-Club-Hotels.0-l553248621532657334-0.Travel-Guide-Filter-Hotels) - [Hotels near The Traces Golf Club ](https://www.expedia.com/The-Traces-Golf-Club-Hotels.0-l6162131-0.Travel-Guide-Filter-Hotels) - [Darlington Hotels ](https://www.expedia.com/Darlington-Hotels.d7558.Travel-Guide-Hotels) - [Flights to Florence ](https://www.expedia.com/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights) - [Flights from Florence ](https://www.expedia.com/lp/flights/1221/flights-from-florence) - [Flights from Effingham ](https://www.expedia.com/lp/flights/553248635975849973/flights-from-effingham) - [Flights to Darlington ](https://www.expedia.com/Cheap-Flights-To-Darlington.d7558.Travel-Guide-Flights) - [Mcleod Regional Medical Center ](https://www.expedia.com/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) - [Visit Florence ](https://www.expedia.com/Florence.dx1221) - [Florence Vacations ](https://www.expedia.com/Florence.d1221.Destination-Travel-Guides) - [Florence Museum ](https://www.expedia.com/Florence-Museum-Florence.d6162137.Vacation-Attraction) - [Francis Marion University ](https://www.expedia.com/Francis-Marion-University-Florence.d6162133.Vacation-Attraction) - [Eastern Carolina Agricultural Fairgrounds ](https://www.expedia.com/Eastern-Carolina-Agricultural-Fairgrounds-Florence.d6162140.Vacation-Attraction) - [Columns Plantation ](https://www.expedia.com/Columns-Plantation-Florence.d553248621532657342.Vacation-Attraction) - [Magnolia Mall ](https://www.expedia.com/Magnolia-Mall-Florence.d6165602.Vacation-Attraction) - [Florence Veterans Park ](https://www.expedia.com/Florence-Veterans-Park-Florence.d619470572411232256.Vacation-Attraction) - [Beaver Creek Golf Club ](https://www.expedia.com/Beaver-Creek-Golf-Club-Darlington.d553248621532657336.Vacation-Attraction) - [Oakdale Country Club ](https://www.expedia.com/Oakdale-Country-Club-Florence.d553248621532657334.Vacation-Attraction) - [Car rentals near Mcleod Regional Medical Center ](https://www.expedia.com/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide) - [Car rentals near Florence ](https://www.expedia.com/Car-Rentals-In-Florence.d1221.Car-Rental-Guide) - [Enterprise Rental Cars in Florence ](https://www.expedia.com/Enterprise-Car-Rentals-In-Florence.d1221-c15.Car-Rental-Guide-Suppliers) - [Minivan Car Rentals in Florence ](https://www.expedia.com/Minivan-Car-Rentals-In-Florence.d1221-tMinivan.Car-Rental-Guide-Class) - [Luxury Car Rentals in Florence ](https://www.expedia.com/Luxury-Car-Rentals-In-Florence.d1221-tLuxury.Car-Rental-Guide-Class) - [Hertz Rental Cars in Florence ](https://www.expedia.com/Hertz-Car-Rentals-In-Florence.d1221-c40.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Florence ](https://www.expedia.com/Budget-Car-Rentals-In-Florence.d1221-c39.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in Florence ](https://www.expedia.com/Avis-Car-Rentals-In-Florence.d1221-c41.Car-Rental-Guide-Suppliers) - [Dollar Rental Cars in Florence ](https://www.expedia.com/Dollar-Car-Rentals-In-Florence.d1221-c1091.Car-Rental-Guide-Suppliers) - [Van Car Rentals in Florence ](https://www.expedia.com/Van-Car-Rentals-In-Florence.d1221-tVan.Car-Rental-Guide-Class) - [Convertible Car Rentals in Florence ](https://www.expedia.com/Convertible-Car-Rentals-In-Florence.d1221-tConvertible.Car-Rental-Guide-Class) - [Alamo Rent A Car Rental Cars in Florence ](https://www.expedia.com/Alamo-Rent-A-Car-Car-Rentals-In-Florence.d1221-c6.Car-Rental-Guide-Suppliers) - [SUV Car Rentals in Florence ](https://www.expedia.com/SUV-Car-Rentals-In-Florence.d1221-tSUV.Car-Rental-Guide-Class) - [Car rentals near Quinby ](https://www.expedia.com/Car-Rentals-In-Quinby.d553248634998841600.Car-Rental-Guide) - [Car rentals near Francis Marion University ](https://www.expedia.com/Car-Rentals-In-Francis-Marion-University.d6162133.Car-Rental-Guide) - [Car rentals near Magnolia Mall ](https://www.expedia.com/Car-Rentals-In-Magnolia-Mall.d6165602.Car-Rental-Guide) - [Car rentals near Peedee ](https://www.expedia.com/Car-Rentals-In-Peedee.d553248635975872954.Car-Rental-Guide) - [Florence Vacation Rentals ](https://www.expedia.com/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals) \*Available to One Key members.