--- title: "$39 Cheap Flights to Isom, KY - Expedia" description: "Looking for cheap flights to Isom? Many airlines offer no change fee on selected flights and book now to earn your airline miles on top of our rewards! Find great 2026 Isom flight deals now!" canonical: "https://www.expedia.com/Cheap-Flights-To-Isom.d3000347378.Travel-Guide-Flights" language: en-US market: US currency: USD prices_as_of: 2026-11-14T15:06:47Z --- # $39 Cheap Flights to Isom, KY [View $39 flight on Sat, Dec 5, 2026](https://www.expedia.com/Flights-Search?leg1=from:FLL,to:AVL,departure:12/5/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:39.00&airProductToken=AQoqCigIx2gSAzQ5MxjlWiCgXSjo%5FZ4DMOH-ngM4SkAAWAFqAkRGcgRKTkVXEgwIARABGAEqAkc0MgAYASIECAEQASgCKAMoBDAN) ## Popular airlines [American Airlines](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Isom,%20Kentucky,%20United%20States%20of%20America,departure:11/28/2026TANYT&leg2=from:Isom,%20Kentucky,%20United%20States%20of%20America,to:CMH,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) [Delta](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Isom,%20Kentucky,%20United%20States%20of%20America,departure:11/28/2026TANYT&leg2=from:Isom,%20Kentucky,%20United%20States%20of%20America,to:CMH,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) [United](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Isom,%20Kentucky,%20United%20States%20of%20America,departure:11/28/2026TANYT&leg2=from:Isom,%20Kentucky,%20United%20States%20of%20America,to:CMH,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) [Southwest Airlines](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Isom,%20Kentucky,%20United%20States%20of%20America,departure:11/28/2026TANYT&leg2=from:Isom,%20Kentucky,%20United%20States%20of%20America,to:CMH,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) [Allegiant Air](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Isom,%20Kentucky,%20United%20States%20of%20America,departure:11/28/2026TANYT&leg2=from:Isom,%20Kentucky,%20United%20States%20of%20America,to:CMH,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"G4"}}]) [Frontier Airlines](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Isom,%20Kentucky,%20United%20States%20of%20America,departure:11/28/2026TANYT&leg2=from:Isom,%20Kentucky,%20United%20States%20of%20America,to:CMH,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) [Alaska Airlines](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:Isom,%20Kentucky,%20United%20States%20of%20America,departure:11/28/2026TANYT&leg2=from:Isom,%20Kentucky,%20United%20States%20of%20America,to:CMH,departure:12/5/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) ## How much is the cheapest flight to Isom? Prices were available within the past 7 days and start at $39 for one-way flights and $76 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select United flight, departing Wed, Dec 9 from Columbus to Knoxville, returning Wed, Dec 16, priced at $300 Found 17 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:TYS,departure:12/9/2026TANYT&leg2=from:TYS,to:CMH,departure:12/16/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:299.90&airProductToken=AQo5CjcI1YIBEgQ0MDcwGII7IJOWASjHq58DMMmtnwM4TkAAWAFqCjFfYmFzaWNlY29yCExBVTJBS0JTCnEKNwjVggESBDQ1MTkYk5YBIK4cKO%5F7nwMw5%5FyfAzhOQABYAWoKMV9iYXNpY2Vjb3IITEFVMkFLQlMKNgjVggESBDE0OTIYrhwggjsopf6fAzCC%5F58DOE5AAFgBagoxX2Jhc2ljZWNvcghMQVUyQUtCUxIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAs) Wed, Dec 9 - Wed, Dec 16 · CMH · TYS · Roundtrip [Select Delta flight, departing Wed, Dec 9 from Columbus to Knoxville, returning Wed, Dec 16, priced at $305 Found 17 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:TYS,departure:12/9/2026TANYT&leg2=from:TYS,to:CMH,departure:12/16/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:304.40&airProductToken=AQpvCjUIxJgBEgQyNDY5GII7IOBcKLSpnwMwm6qfAzhFQABYAWoJTUFJTkJBU0lDcghWQVZTQzJCQwo2CMSYARIENDY2NhjgXCCTlgEo46qfAzClq58DOEVAAVgBaglNQUlOQkFTSUNyCFZBVlNDMkJDCnEKNwjEmAESBDUxOTYYk5YBIOO0ASja-J8DMMf5nwM4RUAAWAFqCU1BSU5CQVNJQ3IIVkFWU0MyQkMKNgjEmAESBDU3NzQY47QBIII7KJX7nwMw1%5FufAzhFQAFYAWoJTUFJTkJBU0lDcghWQVZTQzJCQxIKCAEQARgBKgJETBgBIgQIARABKAIoAygEMAE) Wed, Dec 9 - Wed, Dec 16 · CMH · TYS · Roundtrip [Select American Airlines flight, departing Wed, Dec 9 from Columbus to Knoxville, returning Wed, Dec 16, priced at $305 Found 17 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:TYS,departure:12/9/2026TANYT&leg2=from:TYS,to:CMH,departure:12/16/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:304.40&airProductToken=AQpnCjEIwYIBEgQ2MjQ3GII7IK4cKIGtnwMw6a2fAzhCQABYAWoFQkFTSUNyCE5WQUlLU0JWCjIIwYIBEgQzODM3GK4cIJOWASjXrp8DMMWvnwM4QkABWAFqBUJBU0lDcghOVkFJS1NCVgppCjMIwYIBEgQ1MjM4GJOWASDimgEolPifAzD0-J8DOEJAAFgBagVCQVNJQ3IITlZBSUtTQlYKMgjBggESBDU0ODYY4poBIII7KKf6nwMwjfufAzhCQAFYAWoFQkFTSUNyCE5WQUlLU0JWEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) Wed, Dec 9 - Wed, Dec 16 · CMH · TYS · Roundtrip [Select Southwest Airlines flight, departing Sat, Dec 5 from Columbus to Knoxville, returning Tue, Dec 8, priced at $325 Found 15 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:TYS,departure:12/5/2026TANYT&leg2=from:TYS,to:CMH,departure:12/8/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:324.40&airProductToken=AQphCi4I15wBEgQxNDYyGII7IMFFKPiAnwMwyIGfAzhKQABYAWoDV0dBcgdKWkFWUzJFCi8I15wBEgQzNjg3GMFFIJOWASiJgp8DMO2CnwM4SkABWAFqA1dHQXIHSlpBVlMyRQpgCi4I15wBEgM0NjMYk5YBIKEDKLejnwMw86OfAzhWQABYAWoDV0dBcgdWQkFWTjJFCi4I15wBEgQyMzYxGKEDIII7KM2knwMwnaWfAzhWQAFYAWoDV0dBcgdWQkFWTjJFEgoIARABGAEqAldOGAEiBAgBEAEoAigDKAQwAQ) Sat, Dec 5 - Tue, Dec 8 · CMH · TYS · Roundtrip [Select Frontier Airlines flight, departing Sat, Dec 5 from Columbus to Cincinnati, returning Sun, Dec 13, priced at $406 Found 13 hours ago](https://www.expedia.com/Flights-Search?leg1=from:CMH,to:CVG,departure:12/5/2026TANYT&leg2=from:CVG,to:CMH,departure:12/13/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:405.74&airProductToken=AQpeCi0IxnISBDQxOTAYgjsgzHAoxf6eAzDV%5F54DOFFAAFgBagNFQ09yB1EyMU9YUzgKLQjGchIEMjU0NxjMcCCiNSjPgp8DMOWDnwM4Q0ABWAFqA0VDT3IHQzIxVlhTNgpeCi0IxnISBDE4NDYYojUg4FwogNifAzDw2J8DOFpAAFgBagNFQ09yB1ozMFBYUzYKLQjGchIEMjU0MBjgXCCCOyjY2p8DMLvbnwM4WkABWAFqA0VDT3IHWjMwUFhTNhIKCAEQARgBKgJGORgBIgQIARABKAIoAygEMAE) Sat, Dec 5 - Sun, Dec 13 · CMH · CVG · Roundtrip ## Find the cheapest month to fly from Columbus (CMH) to Knoxville (TYS) ### February is typically the cheapest month to fly From $226 - $486 per traveler. View flights in February Insights are based on prices from searches for economy trips of 10 days or less on our sites in the last 12 months. Insights are informative only and current prices may differ. ## Book with confidence ### Tips to find the cheapest flights to Isom #### The cheapest day to fly Get started finding a cheap flight to Isom on Expedia by either choosing a deal on this page or entering into the search bar your travel dates, origin airport, and whether you want roundtrip or one-way airfare. You can filter for flexibility, number of stops, airline, and departure/arrival times to find the best flight for you. #### The cheapest month to fly December is the cheapest month to fly to Isom. This coincides with the low season when fewer people travel. Whichever month you travel in, though, be sure to book at least a month in advance if you want to score cheap tickets to Isom. ARC's data shows that domestic flights booked 28 days or more before departure are typically 24% cheaper than those booked last minute. #### The most affordable time to book a flight Typically, a Sunday can be the cheapest time to book a flight to Isom, according to ARC’s data. On average, you could save between 6% and 13% by booking on a Sunday instead of a Friday, which is the most expensive day to make a reservation. #### The cheapest round-trip tickets to Isom The lowest price for round-trip flights to Isom in 2026 starts from $76, while one-way tickets start from from $39\. Expedia's effective search tool is one of the best ways to find a budget airfare. Simply enter your dates, and within seconds, it'll show you a vast selection of the cheapest flights to Isom. If you have a preferred departure time or airline, you can use the handy filters to customize your search. #### The cheapest airlines flying to Isom Allegiant Air, United, Delta, Southwest Airlines, American Airlines, Frontier Airlines are just some of the airlines that can typically offer cheap tickets to Isom. You can find their most affordable flights by using the “airline” search filter and then sorting prices from low to high. As a trusted partner of the world's leading airlines, Expedia offers you some of the best airfare deals to Isom and countless more destinations worldwide. #### The most affordable airports to fly into To view the cheapest airports to fly into for Isom, simply order your search results from lowest to highest price. Expedia's search tool compares flight prices for all airports close to your destination, so you don't have to manually search them one by one to find the cheapest flight to Isom. If you have a preferred place to fly into, take advantage of the “arrival airport” filter to narrow down your search on Expedia. #### Save with a package With Expedia's amazing [package deals](https://www.expedia.com/package-deals), you could save hundreds of dollars by booking your Isom plane tickets together with your accommodations, car rental, or activities. Just select the search wizard's “package” option to view some of the cheapest deals. Look out for the green savings label to see how much you're saving. #### Date flexibility for the cheapest flights to Isom If you can be flexible with your travel dates, it's a good idea to broaden your search by comparing prices on different days. This will open up more options, meaning you could uncover a less expensive flight to Isom. #### Stopover savings The cheapest tickets to Isom are sometimes those with a stopover. Book one of these flights, and you'll change planes at an airport en route to Isom. While the overall travel time might be longer than a non-stop flight, you may decide it's worth it for the money saved. #### Get Expedia's Price Drop Protection Price Drop Protection means that if your flight gets cheaper after booking, you'll be credited the difference\*. This gives you peace of mind that you're getting one of the cheapest flights to Isom for your chosen departure. Expedia's Price Drop Protection is available for a small fee but is free to One Key Gold and Platinum tier members. *\*Terms apply.* #### Use our Price Tracking feature Expedia's Price Tracking feature is another great tool that removes the guesswork from finding cheap flights to Isom. Simply download the free Expedia app to your smart device and activate Isom flight price alerts for your travel dates. There's even a price predictor tool that uses historical data to indicate the best time to book, giving you peace of mind that you'll nab the lowest prices. #### Book with Expedia As well as Price Drop Protection and Price Tracking, Expedia's close partnership with a vast selection of the world's leading airlines means you're sure to find cheap flights to Isom. Plus, the One Key rewards program lets you earn real cash rewards on most bookings that you can use to save money on future trips. Best of all, it's free to join, and members often unlock exclusive discounts, too. *Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.* ## Travel information | Destination city name | Knoxville | | ----------------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | | Destination airport | McGhee Tyson Airport | | Destination airport IATA code | TYS | | Airlines serving | American Airlines, Delta, United, Allegiant Air, Southwest Airlines, Alaska Airlines, Air Canada, Lufthansa, British Airways, KLM, Air France, WestJet, Finnair, Virgin Atlantic, Iberia, Aer Lingus, Brussels Airlines, Japan Airlines, LATAM Airlines Group, Korean Air, SAS, Qatar Airways, All Nippon Airways, Avianca, Aeromexico, Qantas Airways, Ethiopian Airlines, Royal Jordanian, Air New Zealand | | Popular airline | American Airlines | | Roundtrip price | $300 | ## Explore a world of travel with Expedia - [Lodging](?equalTargetTab=tab-0) - [Flights](?equalTargetTab=tab-1) - [Packages](?equalTargetTab=tab-2) - [Cars](?equalTargetTab=tab-3) - [Vacation Rentals](?equalTargetTab=tab-4) - [Apartments in Redfox](https://www.expedia.com/Redfox-Apartments.d3000347442-aaApartments.Travel-Guide-Accommodation) - [Hindman Hotels](https://www.expedia.com/Hindman-Hotels.d6338707.Travel-Guide-Hotels) - [B&B in Redfox](https://www.expedia.com/Redfox-Bed-And-Breakfast.d3000347442-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Knott County](https://www.expedia.com/Knott-County-Cabins.d553248635976430960-aaCabins.Travel-Guide-Accommodation) - [Cabin Rentals in Whitesburg](https://www.expedia.com/Whitesburg-Cabins.d183265-aaCabins.Travel-Guide-Accommodation) - [Cabin Rentals in Redfox](https://www.expedia.com/Redfox-Cabins.d3000347442-aaCabins.Travel-Guide-Accommodation) - [Motels in Letcher County](https://www.expedia.com/Letcher-County-Motels.d553248635976430359-aaMotels.Travel-Guide-Accommodation) - [Cabin Rentals in Blackey](https://www.expedia.com/Blackey-Cabins.d553248634998793381-aaCabins.Travel-Guide-Accommodation) - [Cottages in Knott County](https://www.expedia.com/Knott-County-Cottages.d553248635976430960-aaCottages.Travel-Guide-Accommodation) - [Vacation Homes in Letcher County](https://www.expedia.com/Letcher-County-Private-Vacation-Homes.d553248635976430359-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [4 Star Hotels in Pippa Passes](https://www.expedia.com/4Star-Pippa-Passes-Hotels.s40-0-d3000347435.Travel-Guide-Filter-Hotels) - [Pikeville Hotels](https://www.expedia.com/Pikeville-Hotels.d9105.Travel-Guide-Hotels) - [Cabin Rentals in Mallie](https://www.expedia.com/Mallie-Cabins.d553248635975871458-aaCabins.Travel-Guide-Accommodation) - [Apartments in Letcher County](https://www.expedia.com/Letcher-County-Apartments.d553248635976430359-aaApartments.Travel-Guide-Accommodation) - [Cottages in Vicco](https://www.expedia.com/Vicco-Cottages.d3000347498-aaCottages.Travel-Guide-Accommodation) - [Cabin Rentals in Letcher](https://www.expedia.com/Letcher-Cabins.d553248635975850370-aaCabins.Travel-Guide-Accommodation) - [B&B in Letcher](https://www.expedia.com/Letcher-Bed-And-Breakfast.d553248635975850370-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Isom](https://www.expedia.com/Isom-Cabins.d3000347378-aaCabins.Travel-Guide-Accommodation) - [Independent Hotels in Deane](https://www.expedia.com/Deane-Hotels-Independent.0-0-d553248635975873254--bIndependent.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Letcher County](https://www.expedia.com/Letcher-County-Cabins.d553248635976430359-aaCabins.Travel-Guide-Accommodation) - [Cabin Rentals in Pine Top](https://www.expedia.com/Pine-Top-Cabins.d553248635975872052-aaCabins.Travel-Guide-Accommodation) - [Pippa Passes Hotels](https://www.expedia.com/Pippa-Passes-Hotels.d3000347435.Travel-Guide-Hotels) - [Cabin Rentals in Eolia](https://www.expedia.com/Eolia-Cabins.d553248635974904597-aaCabins.Travel-Guide-Accommodation) - [B&B in Whitesburg](https://www.expedia.com/Whitesburg-Bed-And-Breakfast.d183265-aaBedAndBreakfast.Travel-Guide-Accommodation) - [B&B in Letcher County](https://www.expedia.com/Letcher-County-Bed-And-Breakfast.d553248635976430359-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Blackey Hotels](https://www.expedia.com/Blackey-Hotels.d553248634998793381.Travel-Guide-Hotels) - [Vacation Homes in Whitesburg](https://www.expedia.com/Whitesburg-Private-Vacation-Homes.d183265-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cabin Rentals in Scuddy](https://www.expedia.com/Scuddy-Cabins.d553248635975847781-aaCabins.Travel-Guide-Accommodation) - [Cottages in Letcher County](https://www.expedia.com/Letcher-County-Cottages.d553248635976430359-aaCottages.Travel-Guide-Accommodation) - [Whitesburg Hotels](https://www.expedia.com/Whitesburg-Hotels.d183265.Travel-Guide-Hotels) - [3 Star Hotels in Fleming-Neon](https://www.expedia.com/3Star-Fleming-Neon-Hotels.s30-0-d553248634999097085.Travel-Guide-Filter-Hotels) - [Motels in Whitesburg](https://www.expedia.com/Whitesburg-Motels.d183265-aaMotels.Travel-Guide-Accommodation) - [Redfox Hotels](https://www.expedia.com/Redfox-Hotels.d3000347442.Travel-Guide-Hotels) - [B&B in Isom](https://www.expedia.com/Isom-Bed-And-Breakfast.d3000347378-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Vacation Homes in Isom](https://www.expedia.com/Isom-Private-Vacation-Homes.d3000347378-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Vacation Homes in Garner](https://www.expedia.com/Garner-Private-Vacation-Homes.d553248635975854597-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Cabin Rentals in Fleming-Neon](https://www.expedia.com/Fleming-Neon-Cabins.d553248634999097085-aaCabins.Travel-Guide-Accommodation) - [Hazard Hotels](https://www.expedia.com/Hazard-Hotels.d6059435.Travel-Guide-Hotels) - [Vicco Hotels](https://www.expedia.com/Vicco-Hotels.d3000347498.Travel-Guide-Hotels) - [2 Star Hotels in Blackey](https://www.expedia.com/2Star-Blackey-Hotels.s20-0-d553248634998793381.Travel-Guide-Filter-Hotels) - [Deane Hotels](https://www.expedia.com/Deane-Hotels.d553248635975873254.Travel-Guide-Hotels) - [Cottages in Redfox](https://www.expedia.com/Redfox-Cottages.d3000347442-aaCottages.Travel-Guide-Accommodation) - [Cabin Rentals in Hindman](https://www.expedia.com/Hindman-Cabins.d6338707-aaCabins.Travel-Guide-Accommodation) - [Vacation Homes in Blackey](https://www.expedia.com/Blackey-Private-Vacation-Homes.d553248634998793381-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Hindman](https://www.expedia.com/Hindman-Apartments.d6338707-aaApartments.Travel-Guide-Accommodation) - [Cabin Rentals in Pippa Passes](https://www.expedia.com/Pippa-Passes-Cabins.d3000347435-aaCabins.Travel-Guide-Accommodation) - [Flights to Raven](https://www.expedia.com/Cheap-Flights-To-Raven.d3000347440.Travel-Guide-Flights) - [Flights from Fleming-Neon](https://www.expedia.com/lp/flights/553248634999097085/flights-from-fleming-neon) - [Flights from Hollybush](https://www.expedia.com/lp/flights/553248635975848575/flights-from-hollybush) - [Flights to Hellier](https://www.expedia.com/Cheap-Flights-To-Hellier.d3000347364.Travel-Guide-Flights) - [Flights to Elkhorn City](https://www.expedia.com/Cheap-Flights-To-Elkhorn-City.d6193063.Travel-Guide-Flights) - [Flights to Loyall](https://www.expedia.com/Cheap-Flights-To-Loyall.d3000347399.Travel-Guide-Flights) - [Flights to Benham](https://www.expedia.com/Cheap-Flights-To-Benham.d3000438351.Travel-Guide-Flights) - [Flights to Hazard](https://www.expedia.com/Cheap-Flights-To-Hazard.d6059435.Travel-Guide-Flights) - [Flights from Pine Top](https://www.expedia.com/lp/flights/553248635975872052/flights-from-pine-top) - [Flights to Hyden](https://www.expedia.com/Cheap-Flights-To-Hyden.d3000438707.Travel-Guide-Flights) - [Flights to Tram](https://www.expedia.com/Cheap-Flights-To-Tram.d3000347491.Travel-Guide-Flights) - [Flights to Prestonsburg](https://www.expedia.com/Cheap-Flights-To-Prestonsburg.d6059430.Travel-Guide-Flights) - [Flights to Knott County](https://www.expedia.com/Destinations-In-Knott-County.d553248635976430960.Flight-Destinations) - [Flights to Dema](https://www.expedia.com/Cheap-Flights-To-Dema.d3000347310.Travel-Guide-Flights) - [Flights to Jeff](https://www.expedia.com/Cheap-Flights-To-Jeff.d3000347381.Travel-Guide-Flights) - [Flights from Redfox](https://www.expedia.com/lp/flights/3000347442/flights-from-redfox) - [Flights to Whitesburg](https://www.expedia.com/Cheap-Flights-To-Whitesburg.d183265.Travel-Guide-Flights) - [Flights to Viper](https://www.expedia.com/Cheap-Flights-To-Viper.d3000347500.Travel-Guide-Flights) - [Flights from Knott County](https://www.expedia.com/lp/flights/553248635976430960/flights-from-knott-county) - [Flights to Jenkins](https://www.expedia.com/Cheap-Flights-To-Jenkins.d3000438760.Travel-Guide-Flights) - [Flights to Hindman](https://www.expedia.com/Cheap-Flights-To-Hindman.d6338707.Travel-Guide-Flights) - [Flights to Floyd County](https://www.expedia.com/Destinations-In-Floyd-County.d553248635976430883.Flight-Destinations) - [Flights to Pikeville](https://www.expedia.com/Cheap-Flights-To-Pikeville.d9105.Travel-Guide-Flights) - [Flights to Harlan](https://www.expedia.com/Cheap-Flights-To-Harlan.d8279.Travel-Guide-Flights) - [Flights to Phyllis](https://www.expedia.com/Cheap-Flights-To-Phyllis.d3000347432.Travel-Guide-Flights) - [Flights to Harold](https://www.expedia.com/Cheap-Flights-To-Harold.d3000347359.Travel-Guide-Flights) - [Flights to Thousandsticks](https://www.expedia.com/Cheap-Flights-To-Thousandsticks.d3000347486.Travel-Guide-Flights) - [Flights from Whitesburg](https://www.expedia.com/lp/flights/183265/flights-from-whitesburg) - [Flights to Ivel](https://www.expedia.com/Cheap-Flights-To-Ivel.d3000438715.Travel-Guide-Flights) - [Flights to Eastern Kentucky](https://www.expedia.com/Cheap-Flights-To-Eastern-Kentucky.d6059428.Travel-Guide-Flights) - [Flights to Carrie](https://www.expedia.com/Cheap-Flights-To-Carrie.d3000347291.Travel-Guide-Flights) - [Flights to Putney](https://www.expedia.com/Cheap-Flights-To-Putney.d6338693.Travel-Guide-Flights) - [Flights to Buckhorn](https://www.expedia.com/Cheap-Flights-To-Buckhorn.d84092.Travel-Guide-Flights) - [Flights to Evarts](https://www.expedia.com/Cheap-Flights-To-Evarts.d6193051.Travel-Guide-Flights) - [Flights to Vicco](https://www.expedia.com/Cheap-Flights-To-Vicco.d3000347498.Travel-Guide-Flights) - [Flights from Isom](https://www.expedia.com/lp/flights/3000347378/flights-from-isom) - [Flights to Pippa Passes](https://www.expedia.com/Cheap-Flights-To-Pippa-Passes.d3000347435.Travel-Guide-Flights) - [Flights from Garner](https://www.expedia.com/lp/flights/553248635975854597/flights-from-garner) - [Flights from Hindman](https://www.expedia.com/lp/flights/6338707/flights-from-hindman) - [Visit Whitesburg](https://www.expedia.com/Whitesburg.dx183265) - [Visit Hindman](https://www.expedia.com/Hindman.dx6338707) - [Visit Eastern Kentucky](https://www.expedia.com/Eastern-Kentucky.dx6059428) - [Visit Pippa Passes](https://www.expedia.com/Pippa-Passes.dx3000347435) - [Visit Vicco](https://www.expedia.com/Vicco.dx3000347498) - [Car rental Redfox](https://www.expedia.com/Car-Rentals-In-Redfox.d3000347442.Car-Rental-Guide) - [Hertz Rental Cars in Whitesburg](https://www.expedia.com/Hertz-Car-Rentals-In-Whitesburg.d183265-c40.Car-Rental-Guide-Suppliers) - [Car rental Whitesburg](https://www.expedia.com/Car-Rentals-In-Whitesburg.d183265.Car-Rental-Guide) - [Luxury Car Rentals in Redfox](https://www.expedia.com/Luxury-Car-Rentals-In-Redfox.d3000347442-tLuxury.Car-Rental-Guide-Class) - [Car rental Hazard](https://www.expedia.com/Car-Rentals-In-Hazard.d6059435.Car-Rental-Guide) - [Car rental Hindman](https://www.expedia.com/Car-Rentals-In-Hindman.d6338707.Car-Rental-Guide) - [Whitesburg Vacation Rentals](https://www.expedia.com/Whitesburg-Vacation-Rentals.d183265.Travel-Guide-VacationRentals) - [Isom Vacation Rentals](https://www.expedia.com/Isom-Vacation-Rentals.d3000347378.Travel-Guide-VacationRentals) - [Hindman Vacation Rentals](https://www.expedia.com/Hindman-Vacation-Rentals.d6338707.Travel-Guide-VacationRentals) - [Redfox Vacation Rentals](https://www.expedia.com/Redfox-Vacation-Rentals.d3000347442.Travel-Guide-VacationRentals) ## Trending flights to Isom Prices were available within the past 7 days and start at $39 for one-way flights and $76 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select Allegiant Air flight, departing Thu, Dec 17 from Orlando to Cincinnati, returning Mon, Jan 11, priced at $76 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:SFB,to:CVG,departure:12/17/2026TANYT&leg2=from:CVG,to:SFB,departure:1/11/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:75.50&airProductToken=AQoqCigIx2gSAzQyNxiyCSCiNSiyiqADMLSLoAM4SkAAWAFqAkRGcgRKTkVXCioKKAjHaBIDNDE0GKI1ILIJKMydogMwzp6iAzhKQABYAWoCREZyBEpORVcSCggBEAEYASoCRzQYASIECAEQASgCKAMoBDAN) Thu, Dec 17 - Mon, Jan 11 · SFB · CVG · Roundtrip \*Available to One Key members. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/Cheap-Flights-To-Isom.d3000347378.Travel-Guide-Flights en-KR: https://www.expedia.co.kr/en/Cheap-Flights-To-Isom.d3000347378.Travel-Guide-Flights ja-JP: https://www.expedia.co.jp/Cheap-Flights-To-Isom.d3000347378.Travel-Guide-Flights de-AT: https://www.expedia.at/Billigflug-Isom.d3000347378.Reise-Angebote-Flug nl-BE: https://www.expedia.be/Destinations-In-Isom.d3000347378.Vliegtickets en-NZ: https://www.expedia.co.nz/Flights-To-Isom.d3000347378.Travel-Guide-Flights en-US: https://www.expedia.com/Cheap-Flights-To-Isom.d3000347378.Travel-Guide-Flights ```