$56 Cheap Flights to Knoxville, IA

View $56 flight on Wed, Jun 17, 2026Opens in a new window

Popular airlines to Knoxville

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

How much is the cheapest flight to Knoxville?

Prices were available within the past 7 days and start at $56 for one-way flights and $114 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, Jul 1 - Wed, Jul 8
DEN
Denver
DSM
Des Moines
$114 Roundtrip, found 3 days ago
$114
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Jul 1 from Denver to Des Moines, returning Wed, Jul 8, priced at $114 found 3 days ago
Southwest Airlines
Sat, May 2 - Mon, May 4
ATL
Atlanta
DSM
Des Moines
$169 Roundtrip, found 1 day ago
$169
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Sat, May 2 from Atlanta to Des Moines, returning Mon, May 4, priced at $169 found 1 day ago
Delta
Fri, May 8 - Sat, May 9
LAX
Los Angeles
DSM
Des Moines
$217 Roundtrip, just found
$217
Roundtrip
just found
Select Delta flight, departing Fri, May 8 from Los Angeles to Des Moines, returning Sat, May 9, priced at $217 just found
American Airlines
Sat, May 2 - Tue, May 5
LAX
Los Angeles
DSM
Des Moines
$231 Roundtrip, found 3 hours ago
$231
Roundtrip
found 3 hours ago
Select American Airlines flight, departing Sat, May 2 from Los Angeles to Des Moines, returning Tue, May 5, priced at $231 found 3 hours ago
United
Tue, May 12 - Wed, May 13
LAX
Los Angeles
DSM
Des Moines
$246 Roundtrip, found 15 hours ago
$246
Roundtrip
found 15 hours ago
Select United flight, departing Tue, May 12 from Los Angeles to Des Moines, returning Wed, May 13, priced at $246 found 15 hours ago

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city center is 49 minutes. Flights from $467
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city center49 min
Flights from $467

Frequently asked questions

What month is the cheapest to fly to Knoxville?
July is the cheapest month to fly to Knoxville. There's less demand then, so you're likely to get a good deal. Planning your trip outside of school breaks and major holidays could also help you save.
Which US cities have the cheapest flights to Knoxville?
Score cheap flights to Knoxville from Chicago, Denver and Atlanta. These cities typically offer the best fares to this popular destination. But bear in mind that holiday periods, stopovers and demand will also impact rates, so remain flexible and book when you see a bargain.
Which US cities fly direct to Knoxville?
There are 21 US destinations you're able to fly to Knoxville nonstop from. Compare your options by using the "Direct flights only" box on Expedia and pick the ideal starting point for you. Here are a few of the top cities to leave from:

  • Chicago
  • Denver
  • Atlanta
  • Dallas
  • Detroit

How to find a cheap flight to Knoxville?
To snag cheap flights to Knoxville, book well in advance and visit during the off-season months of December and January. Want another helpful tip? Jet off on a Thursday and save around 16% on average compared to those who travel on a Sunday.* Set up price tracking on the Expedia app and we'll update you as soon as your fares drop.*Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.
How to get a cheap last-minute flight to Knoxville?
While booking in advance is generally the best way to save money, don't panic if your Knoxville vacation is last minute. It's still possible to find cheap flights to Knoxville, especially if your plans have a little wiggle room. Try changing your travel dates, exploring different ticket options or flying out of another hub.
How far in advance should I book a flight to Knoxville?
Lock in your flight to Knoxville two to four months ahead if you're visiting from an international destination. For domestic travel, the usual timeframe is 28 days in advance. Cheaper fares and a wider variety of departure dates, schedules and seating options are just some of the awesome benefits of booking early.**Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.
Which day of the week is the cheapest day to buy a plane ticket to Knoxville?
You can usually find cheap flights to Knoxville on a Sunday. Travelers can save around 8% on average compared to those who book on a Friday, which is typically the most expensive day for tickets.**Best day of the week to book, depart and ideal booking window recommendations based on average round-trip ticket prices for January through August 2023, sourced from Airline Reporting Corporation's (ARC) global airline sales database. Percentages noted are averages.
Which airlines fly to Knoxville?
A total of 4 carriers connect 12 airports all over the world to Knoxville. Here are some of the most popular airlines to Knoxville, where Des Moines Intl. Airport (DSM) is the chief entry point:

  • United Airlines
  • American Airlines
  • Delta Air Lines
  • Frontier Airlines

Where do you fly into Knoxville?
If you're flying to Knoxville, the main hub to disembark at is Des Moines Intl. Airport (DSM). Another option is to fly to Knoxville via Ottumwa, IA (OTM-Ottumwa Industrial).
How far is the airport from central Knoxville?
You'll be around 30 mi northwest of the center of Knoxville after touching down at Des Moines Intl. Airport (DSM).
Can I save money by booking a Knoxville trip package?
Bundle your hotel and flight and you could save hundreds of dollars. Better still, you can add extras like tours and car rentals to your Knoxville flight and hotel package deal. With Expedia, it's simple to organize all your Knoxville travel arrangements in the same place.
Can I change or cancel my flight to Knoxville?
You can typically change or cancel your flight to Knoxville within 24 hours of booking. However, keep in mind that some flights are non-refundable. In those cases, you may be issued credit for future flights rather than a direct refund. Make sure you check the airline's terms and conditions in your itinerary for exact details. Use Expedia's "No cancel fee" or "Changes included" filters during your search to find cheap flights to Knoxville with flexible change policies. For additional information, head to our Customer Service Portal.

*Flight schedules are subject to change.

*Available to One Key members.

 

Travel information

Destination airport
Des Moines Intl.
Destination airport IATA code
DSM
Destination city name
Des Moines
Roundtrip price
$114

Trending flights to Knoxville

Prices were available within the past 7 days and start at $56 for one-way flights and $114 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Wed, Jul 1 - Wed, Jul 8
DEN
Denver
DSM
Des Moines
$114 Roundtrip, found 3 days ago
$114
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Wed, Jul 1 from Denver to Des Moines, returning Wed, Jul 8, priced at $114 found 3 days ago

Explore a world of travel with Expedia