De Soto Vacations from $182
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Your De Soto Vacation
Experience the unique character and personality of De Soto with a tailor-made De Soto vacation package. From its welcoming locals to its rich history, you'll never have a boring moment in this city. A trip to De Soto wouldn't be complete without visiting a few top attractions, starting with Victoria Glaces Conservation Area Trailhead. No matter your travel plans or budget, organizing a tailored De Soto vacation is a cinch with Expedia.
The Latest De Soto vacation packages
Price found within the past 48 hours. Click for updated prices.
Hampton Inn By Hilton St Louis Airport
Woodson Terrace
Price was $269, price is now $186 per person
$186
per person
Dec 12 - Dec 14
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (62 reviews)
Good breakfast and comfortable.environment.
Housekeeping did not clean the room on the 2nd day, we requested for service, she entered the room but did not clean it.
Reviewed on Oct 4, 2025
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Price was $264, price is now $188 per person
$188
per person
Dec 12 - Dec 14
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,005 reviews)
Not even a bottle of water in the overpriced room nor paper towels in kitchen. Creamer for coffee was expired. Staff just said it was an “oversight”. Not even an apology or offer to give fresh creamer.
Reviewed on Oct 4, 2025
De Soto Hotel Deals
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
4800 U.S. Highway 67, De Soto, MO
9.4/10 Exceptional! (153 reviews)
Breakfast
"Take the breakfast picture off the website. It said free breakfast for 2 adults but they stopped doing breakfast awhile back"
Reviewed on Sep 12, 2025
Secluded cabin on private property
De Soto
10/10 Exceptional! (57 reviews)
"Very clean inside. The host was responsive to questions in messaging on the app. Crystal laden rocks abound just laying on the forest floor on the property. We had a good time with the family there while we were in town for our niece's wedding at the nearby Hillsboro winery. Very quite and peaceful ..."
Reviewed on Sep 23, 2025
82 Acre Hobby Farm with Lincoln Log Cabin
De Soto
$261 nightly
The price is $271 total per night from Oct 13 to Oct 14
$271 total
Oct 13 - Oct 14
Total with taxes and fees
10/10 Exceptional! (39 reviews)
"Fabulous!!!"
Reviewed on Aug 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
De Soto Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 6,500 |
Max Temp Winter | 45ºF |
Max Temp Summer | 90ºF |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.