De Soto Vacations from $289

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Your De Soto Vacation

Experience the unique character and personality of De Soto with a tailor-made De Soto vacation package. From its welcoming locals to its rich history, you'll never have a boring moment in this city. A trip to De Soto wouldn't be complete without visiting a few top attractions, starting with Victoria Glaces Conservation Area Trailhead. No matter your travel plans or budget, organizing a tailored De Soto vacation is a cinch with Expedia.

The Latest De Soto vacation packages

Price found within the past 48 hours. Click for updated prices.
Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown

3 out of 5
Downtown West
Price was $379, price is now $289 per person
$289
per person
Jun 24 - Jun 26
found 3 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8/10 Very Good! (696 reviews)
Breakfast was decent expected a better variety of food.Room was nice

Reviewed on Mar 31, 2026

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $1,133, price is now $629 per person
$629
per person
May 26 - May 30
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
9.2/10 Wonderful! (1,620 reviews)
The breakfaat was average, thou fresh. There was enough street parking nearby, safe.

Reviewed on Mar 30, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $1,169, price is now $851 per person
$851
per person
May 14 - May 18
found 1 day ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8.6/10 Excellent! (1,009 reviews)
It had unique decor which was fun. Staff was nice But the lights were broken and there was a leftover can under a chair

Reviewed on Apr 1, 2026

Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

3.5 out of 5
Price was $494, price is now $371 per person
$371
per person
May 6 - May 10
found 6 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8/10 Very Good! (1,007 reviews)
Swimming pool wasn't in service

Reviewed on Mar 26, 2026

Marriott St. Louis Airport

Marriott St. Louis Airport

4 out of 5
Edmundson
Price was $633, price is now $492 per person
$492
per person
May 6 - May 10
found 6 hours ago
Roundtrip flight included
Dallas (DFW) to St. Louis (STL)
8/10 Very Good! (1,002 reviews)
The toilet had a leak and even though it said it was a 4 star, other than the bar, i only saw three stars

Reviewed on Feb 21, 2026

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De Soto Hotel Deals

Secluded cabin on private property

Secluded cabin on private property

De Soto MO
10/10 Exceptional! (67 reviews)
had everything we needed everyone enjoyed them self

Reviewed on Mar 30, 2026

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Secluded cabin on private property
82 Acre Hobby Farm with Lincoln Log Cabin

82 Acre Hobby Farm with Lincoln Log Cabin

De Soto MO
10/10 Exceptional! (41 reviews)
The cabin was cozy; comfortable; clean; everything we needed; decorated nicely plus Christmas tree and decor; friendly and attentive hosts. There are not enough nice things to say about them. If I could rate it a 20 out of 10 I would. We will stay again if available next time!! There were home laid ...

Reviewed on Dec 8, 2025

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82 Acre Hobby Farm with Lincoln Log Cabin
Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

2.5 out of 5
1201 Drury Ln Arnold MO
Fully refundableReserve now, pay when you stay
$86 nightly
The price is $99 total per night from Apr 9 to Apr 10
$99 total
Apr 9 - Apr 10
Total with taxes and fees
9.4/10 Exceptional! (1,000 reviews)
Clean room, comfortable bed, free breakfast & plenty of fast food places nearby

Reviewed on Mar 23, 2026

Pear Tree Inn St. Louis Arnold
See all 182 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best De Soto Vacation Packages

De Soto Essential Information

Language
English
Currency
U.S dollars
Population
6,500
Max Temp Winter
45ºF
Max Temp Summer
90ºF

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Frequently asked questions

How much does a De Soto vacation package cost?
Offering excellent value package deals from $289 on Expedia, you'll be surprised at how little a vacation to De Soto costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to De Soto?
If you're looking to score a cheap De Soto vacation package, consider planning a trip in June, October and November. You're likely to find lower prices on airfares and hotels during these months — perfect for a budget-friendly break.
How many days is enough for De Soto?
Generally, a handful of days is enough to tick off the top sights during your De Soto vacation. However, if you'd like to have time to relax or take day tours, think about extending your trip.
How to find the best De Soto package deals?
Use Expedia's filters to help you find some tempting De Soto package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your trip for midweek, or search for De Soto package deals in the off-peak season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a De Soto vacation as a package?
You can enjoy significant savings on your next De Soto retreat by booking a personalized vacation package. Check the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundling can save travelers hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to De Soto?
If you're considering a spontaneous De Soto adventure, browse our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can land terrific deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later De Soto vacation packages?
Set off on your dream trip to De Soto with help from our Book Now, Pay Later vacations. No need to scrimp and save or wait until payday — we've joined forces with online lender Affirm to give you more flexibility with your finances. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stay on budget and snap up cheap deals before they sell out.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.