
De Soto Vacations from $399
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Your De Soto Vacation
Experience the unique character and personality of De Soto with a tailor-made De Soto vacation package. From its welcoming locals to its rich history, you'll never have a boring moment in this city. A trip to De Soto wouldn't be complete without visiting a few top attractions, starting with Victoria Glaces Conservation Area Trailhead. No matter your travel plans or budget, organizing a tailored De Soto vacation is a cinch with Expedia.
The Latest De Soto vacation packages
Price found within the past 48 hours. Click for updated prices.

The Westin St. Louis
Downtown St. Louis
Price was $516, price is now $399 per person
$399
per person
May 8 - May 12
found 8 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,007 reviews)
Wonderful first time stay at this hotel. We will be back. Only suggestion would be for the meat selection at breakfast buffets it was slightly over cooked each day.
Reviewed on Apr 2, 2026

The Cheshire
Save 100% on your flight
Price was $696, price is now $472 per person
$472
per person
May 8 - May 12
found 8 hours ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,009 reviews)
It had unique decor which was fun. Staff was nice But the lights were broken and there was a leftover can under a chair
Reviewed on Apr 1, 2026

The Wildwood Hotel
Price was $900, price is now $662 per person
$662
per person
May 13 - May 16
found 13 hours ago
Roundtrip flight included
New York (JFK) to St. Louis (STL)
9.2/10 Wonderful! (1,627 reviews)
The breakfaat was average, thou fresh. There was enough street parking nearby, safe.
Reviewed on Mar 30, 2026


DoubleTree by Hilton St. Louis Forest Park
Central West End
Price was $1,091, price is now $889 per person
$889
per person
May 13 - May 16
found 13 hours ago
Roundtrip flight included
New York (JFK) to St. Louis (STL)
8.2/10 Very Good! (1,001 reviews)
Kevin at the front desk was kind, courteous and most friendly— super nice and accommodating young fellow. Also, Liz, who works her rear end off at the morning breakfast is amazing— worth a good tip every day. Super disappointed, however, in the breakfast—NO fault of Liz or her crew that works for breakfast. Have been going to this hotel at least once a year for many years now. They always have various college, possibly high school teams in the Hotel. This year, the teams seem to be less courteous and have to wonder how their rooms look when they left. They would come to the breakfast and devour simply everything. As an example this morning, I was there before 8 AM and basically all that was left with scrambled eggs and some sausage links. No fruit, no milk for cereal no oatmeal no bagels or pastries and even all the juices were empty. Several people in my party did not have breakfast included with the room and I paid an extra $20 a day to get nothing to eat. Several people that came after 8 AM were very upset and I feel Hilton will lose customers over having these teams in House. Wondering if these teams are more stable than the average paying customer. Also in the room itself I feel the bathroom desperately needs some updating. Old-fashioned very low toilets and the caulking in my shower around the toilet was not only unsightly, but I wondered how clean. Also, the bed in the room I was in with dreadful. very disappointed in our trip there this time.
Reviewed on Mar 29, 2026
De Soto Hotel Deals

Secluded cabin on private property
De Soto MO
10/10 Exceptional! (67 reviews)
had everything we needed everyone enjoyed them self
Reviewed on Mar 30, 2026

82 Acre Hobby Farm with Lincoln Log Cabin
De Soto MO
10/10 Exceptional! (41 reviews)
The cabin was cozy; comfortable; clean; everything we needed; decorated nicely plus Christmas tree and decor; friendly and attentive hosts. There are not enough nice things to say about them. If I could rate it a 20 out of 10 I would. We will stay again if available next time!! There were home laid ...
Reviewed on Dec 8, 2025

Pear Tree Inn St. Louis Arnold
1201 Drury Ln Arnold MO
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $104 total per night from Apr 13 to Apr 14
$104 total
Apr 13 - Apr 14
Total with taxes and fees
9.4/10 Exceptional! (1,004 reviews)
Clean, comfortable. A bit noisy on the highway side.
Reviewed on Apr 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best De Soto Vacation Packages
De Soto Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Population | 6,500 |
Max Temp Winter | 45ºF |
Max Temp Summer | 90ºF |
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