De Soto Vacations from $291

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Your De Soto Vacation

Experience the unique character and personality of De Soto with a tailor-made De Soto vacation package. From its welcoming locals to its rich history, you'll never have a boring moment in this city. A trip to De Soto wouldn't be complete without visiting a few top attractions, starting with Victoria Glaces Conservation Area Trailhead. No matter your travel plans or budget, organizing a tailored De Soto vacation is a cinch with Expedia.

The Latest De Soto vacation packages

Price found within the past 48 hours. Click for updated prices.
The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
Sep 16 - Sep 18
found 5 hours ago
Roundtrip flight included
Las Vegas (LAS) to St. Louis (STL)
9/10 Wonderful! (1,547 reviews)
Property is well kept.

Reviewed on Jul 2, 2025

Ballpark Apartments by Barsala

Ballpark Apartments by Barsala

4 out of 5
Downtown St. Louis
per person
Aug 15 - Aug 17
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to St. Louis (STL)
7.2/10 Good! (7 reviews)
It's a great location, right across from the Ballpark. It is a fairly spartan apartment set-up, with concrete floors.. a little surprising? Parking is on the street or in a pay lot.

Reviewed on Jun 8, 2025

The Principal Hotel

The Principal Hotel

3.5 out of 5
per person
Aug 7 - Aug 11
found 6 hours ago
Roundtrip non-stop flight included
Miami (MIA) to St. Louis (STL)
9.8/10 Exceptional! (79 reviews)
We live in Mo. We come often to visit family. We love staying at the Principal.

Reviewed on Jul 5, 2025

Spacious 3-Bedroom with King Bed

Spacious 3-Bedroom with King Bed

4 out of 5
Central West End
Save 100% on your flight
per person
Aug 7 - Aug 11
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to St. Louis (STL)
9.2/10 Wonderful! (9 reviews)
Overall, we loved the apartment. It was cute, beds were very comfortable.

Reviewed on May 8, 2025

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
per person
Sep 16 - Sep 18
found 5 hours ago
Roundtrip flight included
Las Vegas (LAS) to St. Louis (STL)
8.4/10 Very Good! (1,000 reviews)
Unacceptable that for this price, NO MICROWAVE IN ROOM! Also under 21 not allowed in any pool at anytime! So do not come here with your Family! Also, only a couple Resteraunts allow kids

Reviewed on Jul 1, 2025

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De Soto Hotel Deals

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Fully refundable
$161 nightly
The price is $172 total per night from Jul 20 to Jul 21
$172 total
Jul 20 - Jul 21
Total includes taxes and fees
9.2/10 Wonderful! (145 reviews)
"Lots of activity’s for Adults and children. Great property. Rooms were nice."

Reviewed on Jul 3, 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
82 Acre Hobby Farm with Lincoln Log Cabin
82 Acre Hobby Farm with Lincoln Log Cabin
De Soto
$269 nightly
The price is $279 total per night from Jul 28 to Jul 29
$279 total
Jul 28 - Jul 29
Total includes taxes and fees
10/10 Exceptional! (37 reviews)
Comfy and peaceful
"Had a great stay enjoyed the beds, porches and the chickens. Great mornings listening to the birds."

Reviewed on Jun 1, 2025

82 Acre Hobby Farm with Lincoln Log Cabin
Secluded cabin on private property
Secluded cabin on private property
De Soto
10/10 Exceptional! (51 reviews)
"Beautiful quiet setting nice property"

Reviewed on Jun 30, 2025

Get rates
Secluded cabin on private property
See all 168 properties in De Soto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best De Soto Vacation Packages

De Soto Essential Information

Language
English
Currency
U.S dollars
Population
6,500
Max Temp Winter
45ºF
Max Temp Summer
90ºF

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Frequently asked questions

How much does a De Soto vacation package cost?
Offering excellent value package deals from $291 on Expedia, you'll be surprised at how little a vacation to De Soto costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to De Soto?
If you're looking to score a cheap De Soto vacation package, consider planning a trip in June, October and November. You're likely to find lower prices on airfares and hotels during these months --- perfect for a budget-friendly break.
How many days is enough for De Soto?
Generally, a handful of days is enough to tick off the top sights during your De Soto vacation. However, if you'd like to have time to relax or take day tours, think about extending your trip.
How to find the best De Soto package deals?
Use Expedia's filters to help you find some tempting De Soto package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your trip for midweek, or search for De Soto package deals in the off-peak season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a De Soto vacation as a package?
You can enjoy significant savings on your next De Soto retreat by booking a personalized vacation package. Check the "Package" heading, then select your travel dates and destination to see the best hotel and flight prices. Bundling can save travelers hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to De Soto?
If you're considering a spontaneous De Soto adventure, browse our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can land terrific deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later De Soto vacation packages?
Set off on your dream trip to De Soto with help from our Book Now, Pay Later vacations. No need to scrimp and save or wait until payday --- we've joined forces with online lender Affirm to give you more flexibility with your finances. Our vacation packages with payment plans mean you can spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stay on budget and snap up cheap deals before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.