Title: Defiance, MO Cottage Rentals from $353 | Expedia.com [Defiance Travel Guide](https://expedia.com/Defiance.dx6353634)[Hotels in Defiance](https://expedia.com/Defiance-Hotels.d6353634.Travel-Guide-Hotels)[Vacation Rentals in Defiance](https://expedia.com/Defiance-Vacation-Rentals.d6353634.Travel-Guide-VacationRentals)[Flights to Defiance](https://expedia.com/Cheap-Flights-To-Defiance.d6353634.Travel-Guide-Flights)[Car Rentals in Defiance](https://expedia.com/Car-Rentals-In-Defiance.d6353634.Car-Rental-Guide)[Defiance Vacation Packages](https://expedia.com/Defiance.d6353634.Destination-Travel-Guides) ![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=6353634&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Defiance cottages ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/90fd5cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/943c3aee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/w2033h1365x15y0-e5f03757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/bc9c69f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Blake Cottage Wine Country Home [](https://www.expedia.com/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information) Augusta 8.4/10 Very Good (9 reviews) "We loved the cottage and the town of Augusta. Would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyler S. $317 nightly $353 total Mar 9 - Mar 10 Total with taxes and fees [](https://www.expedia.com/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/126000000/125130000/125122500/125122473/ea5d4b72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/126000000/125130000/125122500/125122473/f21ecd44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/126000000/125130000/125122500/125122473/3980b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125130000/125122500/125122473/f66eadab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 508: The Secret Sojourn by JZ Vacation Rentals [](https://www.expedia.com/St-Louis-Hotels-508-The-Secret-Sojourn-By-JZ-Vacation-Rentals.h125122473.Hotel-Information) O'Fallon $489 nightly $576 total Mar 18 - Mar 19 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-508-The-Secret-Sojourn-By-JZ-Vacation-Rentals.h125122473.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23®ionId=6353634&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=AA_SPRING_PROMO_6353634) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=CABIN) Cottages [](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=COTTAGE) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=VACATION_HOME) Apartments [](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=APARTMENT) Condos [](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=CONDO) Aparthotels [](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=APART_HOTEL) Chalets [](https://www.expedia.com/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-05&d1=2026-06-05&endDate=2026-06-08&d2=2026-06-08&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Cottages.d6353634-aaCottages.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Cottages.d6353634-aaCottages.Travel-Guide-Accommodation) ## Top Defiance Hotel Reviews ![Comfort Suites St Charles - St Louis](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/6093d918_y.jpg) ### Comfort Suites St Charles - St Louis 8/10 Good "Over all our stay was good. The room was a good size, we are thankful there was an ironing board and iron in the room. Good options at breakfast and the staff we encountered we are very pleasant. " [](https://expedia.com/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/bfca870c_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "Nice staff" [](https://expedia.com/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Drury Plaza Hotel St. Louis Chesterfield](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/69d580ec_y.jpg) ### Drury Plaza Hotel St. Louis Chesterfield 8/10 Good "The staff was super friendly and professional and we had a great start. The breakfast was not great; food was cold and some of it didn’t seem fresh. Overall it was still a good stay!" [](https://expedia.com/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![Crowne Plaza St. Louis Airport by IHG](https://images.trvl-media.com/lodging/1000000/10000/3100/3010/45ba14e8_y.jpg) ### Crowne Plaza St. Louis Airport by IHG 4/10 Poor "No hot water day of checkout, furniture and walls in room in poor condition, could not print receipt at checkout." [](https://expedia.com/St-Louis-Hotels-Crowne-Plaza-St-Louis-Airport.h3010.Hotel-Information) ![Drury Inn & Suites Southwest St. Louis](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/416a6a90_y.jpg) ### Drury Inn & Suites Southwest St. Louis 10/10 Excellent "Clean room, great kickback and breakfast. " [](https://expedia.com/St-Louis-Hotels-Drury-Inn-Suites-Southwest-St-Louis.h976140.Hotel-Information) ![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2_y.jpg) ### Country Inn & Suites by Radisson, St. Charles Historic District 8/10 Good "Good " [](https://expedia.com/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c_y.jpg) ### The Wildwood Hotel 10/10 Excellent "2nd time was as good as the first. " [](https://expedia.com/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Sonesta ES Suites St. Louis - Chesterfield](https://images.trvl-media.com/lodging/1000000/10000/500/422/6f160867_y.jpg) ### Sonesta ES Suites St. Louis - Chesterfield 8/10 Good "Good" [](https://expedia.com/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information) ![Elimwood Hotel, a Ramada by Wyndham](https://images.trvl-media.com/lodging/1000000/30000/25500/25401/6eb87806_y.jpg) ### Elimwood Hotel, a Ramada by Wyndham 6/10 Okay "Room was clean" [](https://expedia.com/St-Louis-Hotels-Elimwood-Hotel.h25401.Hotel-Information) ## Find out more about Defiance ## Defiance Cottages information | Number of reviews | 9 | | ----------------- | ----------- | | Accommodation | 42 Cottages | | Lowest Price | $353 | | Highest Price | $576 | ## Frequently asked questions ### How much do cottages in Defiance cost? ### Why book your cottage in Defiance with Expedia? ### How can I find cheap cottages in Defiance? ### What is there to do in Defiance near my cottage? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Yellow Farmhouse Winery ](https://www.expedia.com/Yellow-Farmhouse-Winery-Hotels.0-l553248621532648568-0.Travel-Guide-Filter-Hotels) - [Hotels near Chandler Hill Vineyards ](https://www.expedia.com/Chandler-Hill-Vineyards-Hotels.0-l553248621532648567-0.Travel-Guide-Filter-Hotels) - [Hotels near Sugar Creek Winery ](https://www.expedia.com/Sugar-Creek-Winery-Hotels.0-l553248621532648612-0.Travel-Guide-Filter-Hotels) - [Villas in Saint Albans ](https://www.expedia.com/Saint-Albans-Villas.d3000445473-aaVillas.Travel-Guide-Accommodation) - [Cottages in Saint Albans ](https://www.expedia.com/Saint-Albans-Cottages.d3000445473-aaCottages.Travel-Guide-Accommodation) - [Vacation Homes in Saint Albans ](https://www.expedia.com/Saint-Albans-Private-Vacation-Homes.d3000445473-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Hamburg Hotels ](https://www.expedia.com/Hamburg-Hotels.d553248635975869538.Travel-Guide-Hotels) - [Saint Albans Hotels ](https://www.expedia.com/Saint-Albans-Hotels.d3000445473.Travel-Guide-Hotels) - [Hotels near Historic Daniel Boone Home and Heritage Center ](https://www.expedia.com/Historic-Daniel-Boone-Home-And-Heritage-Center-Hotels.0-l553248621532648566-0.Travel-Guide-Filter-Hotels) - [Hotels near Babler State Park ](https://www.expedia.com/Babler-State-Park-Hotels.0-l6293012-0.Travel-Guide-Filter-Hotels) - [Hotels near Dr. Edmund A. 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[Yellow Farmhouse Winery ](https://www.expedia.com/Yellow-Farmhouse-Winery-Defiance.d553248621532648568.Vacation-Attraction) - [Chandler Hill Vineyards ](https://www.expedia.com/Chandler-Hill-Vineyards-Defiance.d553248621532648567.Vacation-Attraction) - [Sugar Creek Winery ](https://www.expedia.com/Sugar-Creek-Winery-Defiance.d553248621532648612.Vacation-Attraction) - [Visit Saint Albans ](https://www.expedia.com/Saint-Albans.dx3000445473) - [Historic Daniel Boone Home and Heritage Center ](https://www.expedia.com/Historic-Daniel-Boone-Home-And-Heritage-Center-Defiance.d553248621532648566.Vacation-Attraction) - [Babler State Park ](https://www.expedia.com/Babler-State-Park-St-Louis.d6293012.Vacation-Attraction) - [Dr. Edmund A. 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Busch Memorial Conservation Area ](https://www.expedia.com/August-A-Busch-Memorial-Conservation-Area-St-Louis.d6160337.Vacation-Attraction) - [Broemmelsiek Park ](https://www.expedia.com/Broemmelsiek-Park-St-Louis.d553248621561876810.Vacation-Attraction) - [Augusta Vacations ](https://www.expedia.com/Augusta.d6250878.Destination-Travel-Guides) - [Visit Weldon Spring Heights ](https://www.expedia.com/Weldon-Spring-Heights.dx6252562) - [St. Louis Premium Outlets ](https://www.expedia.com/St-Louis-Premium-Outlets-St-Louis.d553248621561876860.Vacation-Attraction) - [Missouri Bluffs Golf Course ](https://www.expedia.com/Missouri-Bluffs-Golf-Course-St-Louis.d553248621532648614.Vacation-Attraction) - [Augusta Winery ](https://www.expedia.com/Augusta-Winery-Augusta.d553248621532648562.Vacation-Attraction) - [Car rentals near Hamburg ](https://www.expedia.com/Car-Rentals-In-Hamburg.d553248635975869538.Car-Rental-Guide) - [Car rentals near Saint Albans ](https://www.expedia.com/Car-Rentals-In-Saint-Albans.d3000445473.Car-Rental-Guide) - [Car rentals near Babler State Park ](https://www.expedia.com/Car-Rentals-In-Babler-State-Park.d6293012.Car-Rental-Guide) - [Car rentals near Augusta ](https://www.expedia.com/Car-Rentals-In-Augusta.d6250878.Car-Rental-Guide) - [Midway Car Rental Rental Cars in Augusta ](https://www.expedia.com/Midway-Car-Rental-Car-Rentals-In-Augusta.d6250878-c27.Car-Rental-Guide-Suppliers) - [Car rentals near Weldon Spring Heights ](https://www.expedia.com/Car-Rentals-In-Weldon-Spring-Heights.d6252562.Car-Rental-Guide) - [Car rentals near Weldon Spring ](https://www.expedia.com/Car-Rentals-In-Weldon-Spring.d553248634983495338.Car-Rental-Guide) - [Car rental St. Louis Airport (SUS) ](https://www.expedia.com/Car-Rentals-In-Spirit-Of-St-Louis.d6024951.Car-Rental-Guide) - [Enterprise Rental Cars in Spirit of St. Louis ](https://www.expedia.com/Enterprise-Car-Rentals-In-Spirit-Of-St-Louis.d6024951-c15.Car-Rental-Guide-Suppliers) - [Budget Rental Cars in Spirit of St. Louis ](https://www.expedia.com/Budget-Car-Rentals-In-Spirit-Of-St-Louis.d6024951-c39.Car-Rental-Guide-Suppliers) - [Augusta Vacation Rentals ](https://www.expedia.com/Augusta-Vacation-Rentals.d6250878.Travel-Guide-VacationRentals) - [Weldon Spring Heights Vacation Rentals ](https://www.expedia.com/Weldon-Spring-Heights-Vacation-Rentals.d6252562.Travel-Guide-VacationRentals) - [Things to do in Augusta ](https://www.expedia.com/Things-To-Do-In-Augusta.d6250878.Travel-Guide-Activities)