Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Des Moines

Best deal Best deal Jul 6 - Jul 8
Tonight Tonight Jun 18 - Jun 19
This weekend This weekend Jun 22 - Jun 24
Next weekend Next weekend Jun 29 - Jul 1

Featured Des Moines Independent Hotels

See all 145 Hotels in Des Moines
Wildwood Lodge

Wildwood Lodge

11431 Forest Ave, Clive
  • Free Cancellation
  • Reserve now, pay when you stay
3.0 out of 5.0
 
 
4.5 out of 5 (1,600 reviews)
True to its name Wildwood Lodge won't disappoint you if you are looking for unique atmosphere. My daughter was panic … - 

Wildwood Lodge$89

Wildwood Lodge$89
Sterling Hotel and Suites

Sterling Hotel and Suites

11428 Forest Ave, Clive
  • Free Cancellation
  • Reserve now, pay when you stay
3.0 out of 5.0
 
 
3.6 out of 5 (1,787 reviews)
Convenient location Location is close to the interstate and there are many dinning options close by. Great for dog - 

Sterling Hotel and Suites$67

Sterling Hotel and Suites$67
Stoney Creek Hotel & Conference Center Des Moines

Stoney Creek Hotel & Conference Center Des Moines

5291 Stoney Creek Court, Johnston
  • Free Cancellation
  • Reserve now, pay when you stay
2.0 out of 5.0
 
 
4.5 out of 5 (961 reviews)
Comfortable and clean The hotel staff was extremely friendly and the entire check in process was very quick. We go to our … - 

Stoney Creek Hotel & Conference Center Des Moines$99

Stoney Creek Hotel & Conference Center Des Moines$99
Des Lux Hotel

Des Lux Hotel

800 Locust St, Des Moines
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 
4.6 out of 5 (502 reviews)
nicely renovated hotel The Des Lux hotel is a nicely renovated hotel with many of the options visitors expect today includ … - 

Des Lux Hotel$139

Des Lux Hotel$139
Prairie Meadows Casino, Racetrack & Hotel

Prairie Meadows Casino, Racetrack & Hotel

1 Prairie Meadows Drive, Altoona
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 
4.6 out of 5 (419 reviews)
Great Place to stay! Great place to stay, room was wonderful, very comfortable. Breakfast buffet was good. I thought the … - 

Prairie Meadows Casino, Racetrack & Hotel$152

Prairie Meadows Casino, Racetrack & Hotel$152
Windsor Court

Windsor Court

6500 Hickman Rd, Windsor Heights
  • Free Cancellation
  • Reserve now, pay when you stay
2.5 out of 5.0
 
 
3.1 out of 5 (43 reviews)
Great place! Oustanding!☆ I travel alot for work. This was the best I've been treated. Clean cozy and very nice … - 

Windsor Court$40

Windsor Court$40
My Place Hotel-Ankeny/ Des Moines, IA

My Place Hotel-Ankeny/ Des Moines, IA

2506 SE Tones Drive, Ankeny
  • Free Cancellation
  • Reserve now, pay when you stay
2.5 out of 5.0
 
 
4.7 out of 5 (27 reviews)
Awesome Hotel! We were very pleased with our stay. Attentive, helpful staff and very clean and comfortable rooms. … - 

My Place Hotel-Ankeny/ Des Moines, IA$92

My Place Hotel-Ankeny/ Des Moines, IA$92
Adventureland Inn

Adventureland Inn

3200 Adventureland Dr, Altoona
    2.5 out of 5.0
     
     
    4.0 out of 5 (143 reviews)
    Good Times Off season but we had a blast. Quiet except for our noise makers. We will do it again! Good price a … - 
    My Place Hotel - Altoona/Des Moines, IA

    My Place Hotel - Altoona/Des Moines, IA

    2315 Adventureland Drive, Altoona
    • Free Cancellation
    • Reserve now, pay when you stay
    2.5 out of 5.0
     
     
    4.6 out of 5 (29 reviews)
    Great value with friendly staff What a great find in Altoona! Located next to casino with a shuttle! The manager at check in (Dee) … - 

    My Place Hotel - Altoona/Des Moines, IA$119

    My Place Hotel - Altoona/Des Moines, IA$119
    Village Inn Motel Des Moines

    Village Inn Motel Des Moines

    1348 East Euclid Ave, Des Moines
      2.0 out of 5.0
       
       
      3.4 out of 5 (344 reviews)
      Decent Price for a decent room It wasn't too bad. For the amount I paid i expected no more or less. The staff was friendly and hel … - 

      Village Inn Motel Des Moines$70

      Village Inn Motel Des Moines$70
      Colfax Inn

      Colfax Inn

      1402 N Walnut St, Colfax
      • Free Cancellation
      • Reserve now, pay when you stay
      2.0 out of 5.0
       
       
      3.1 out of 5 (816 reviews)
      Nice and quiet Arrived at this motel a little later than I anticipated but it was ok because the front desk person … - 

      Colfax Inn$57

      Colfax Inn$57
      Apple Tree Inn

      Apple Tree Inn

      1215 North Jefferson Way, Indianola
      • Free Cancellation
      • Reserve now, pay when you stay
      2.5 out of 5.0
       
       
      4.2 out of 5 (4 reviews)
      Nice hotel close to eating The room was large, pleasant, comfortable and clean. The bathroom was fresh and clean. The breakfas … - 

      Apple Tree Inn$71

      Apple Tree Inn$71
      Cozy Rest Motel

      Cozy Rest Motel

      2316 Southeast 14th Street, Des Moines
        2.0 out of 5.0
         
         
        3.7 out of 5 (320 reviews)
        Gives you a night's rest and a shower... It was clean enough, high bed, not a big room, but started getting messages my facebook was being h … - 

        Cozy Rest Motel$65

        Cozy Rest Motel$65
        Covered Bridge Inn

        Covered Bridge Inn

        1312 Cedar Bridge Rd., Winterset
        • Free Cancellation
        • Reserve now, pay when you stay
        2.5 out of 5.0
         
         
        4.4 out of 5 (99 reviews)
        So comfy Room and staff so comfy. Will recommend this place to everyone 💑 - 

        Covered Bridge Inn$89

        Covered Bridge Inn$89
        Boulders Inn & Suites Polk City

        Boulders Inn & Suites Polk City

        300 Boulder Pointe, Polk City
        • Free Cancellation
        • Reserve now, pay when you stay
        2.5 out of 5.0
         
         
        4.3 out of 5 (211 reviews)
        Wonderful stay in a quiet little town On the plus side, Boulder Inn had a friendly staff, large rooms with very comfortable mattresses, l … - 

        Boulders Inn & Suites Polk City$85

        Boulders Inn & Suites Polk City$85
        Hotel Pattee

        Hotel Pattee

        1112 Willis Ave, Perry
        • Free Cancellation
        • Reserve now, pay when you stay
        3.0 out of 5.0
         
         
        4.6 out of 5 (130 reviews)
        I love staying at this hotel! We have stayed at the Hotel Pattee several times over the years. It is a unique and beautiful hotel … - 

        Hotel Pattee$129

        Hotel Pattee$129
        Edgetowner Motel

        Edgetowner Motel

        804 Guthrie St, De Soto
          2.5 out of 5.0
           
           
          3.1 out of 5 (19 reviews)
          Gold Star Staff! peaceful. - patch

          Edgetowner Motel$62

          Edgetowner Motel$62
          Cobblestone Inn & Suites - Winterset, IA

          Cobblestone Inn & Suites - Winterset, IA

          1304 North 4th Avenue, Winterset
          • Free Cancellation
          • Reserve now, pay when you stay
          2.5 out of 5.0
           
           
          4.2 out of 5 (102 reviews)
          My kind of place This is a clean and comfortable place with free breakfast under $100. I can’t afford luxury hotels … - 

          Cobblestone Inn & Suites - Winterset, IA$110

          Cobblestone Inn & Suites - Winterset, IA$110
          For Work or Play Downtown is Just a Mile Away!

          For Work or Play Downtown is Just a Mile Away!

          , Des Moines
             
             
            Relax Inn

            Relax Inn

            4144 Hubbell Ave, Des Moines
            • Free Cancellation
            • Reserve now, pay when you stay
            2.0 out of 5.0
             
             
            3.1 out of 5 (15 reviews)
            not good worst stay ever - 

            Relax Inn$65

            Relax Inn$65
            Map

            Recently booked Des Moines hotels

            TownePlace Suites by Marriott - Des Moines Urbandale
            2.5 out of 5.0
            Last booking: 55 minutes ago
            Super 8 by Wyndham Altoona
            2.5 out of 5.0
            Last booking: 55 minutes ago
            La Quinta Inn & Suites Des Moines/West-Clive
            2.5 out of 5.0
            Last booking: 1 hour ago
            Microtel Inn & Suites by Wyndham Urbandale/Des Moines
            2.0 out of 5.0
            Last booking: 1 hour ago
            Best Western Plus Des Moines West Inn & Suites
            2.5 out of 5.0
            Last booking: 1 hour ago
            WoodSpring Suites Ankeny
            2.5 out of 5.0
            Last booking: 1 hour ago
            Super 8 by Wyndham Clive/W Des Moines
            2.0 out of 5.0
            Last booking: 1 hour ago
            Des Lux Hotel
            3.5 out of 5.0
            Last booking: 2 hours ago

            Independent Des Moines Hotel Guide

            Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Des Moines, Iowa. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Des Moines hotels guarantees an unparalleled level of comfort and quality.

            You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Des Moines Independent locations may even offer extra little benefits and discounts for frequent travelers.