Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Downtown Cincinnati Business Hotels

See all 222 Hotels in Downtown Cincinnati
Millennium Cincinnati

Millennium Cincinnati

150 West 5th Street, Cincinnati
3.5 out of 5.0
3.4 out of 5 (5,781 reviews)
Cincinnati Excellence...Although we only stayed 1 night our room was excellent...and the staff was great as well!
  Dec 23, 2017

$88

$88
Hilton Cincinnati Netherland Plaza

Hilton Cincinnati Netherland Plaza

35 W 5th St, Cincinnati
4.5 out of 5.0
4.3 out of 5 (1,281 reviews)
Nie hotel in the heart of downtown.Stayed here for a wedding recently - the room was large and spacious. Service was great and the staff were very friendly.
  Jan 7, 2018

$144

$144
The Westin Cincinnati

The Westin Cincinnati

21 E 5th St, Cincinnati
4.0 out of 5.0
4.3 out of 5 (1,508 reviews)
Quiet & ConvenientQuick and very friendly check-in. Our room overlooked the Fountain Square and was spacious, quiet and clean! Conveniently located to restaurants and to Aronoff Center. A very nice stay overall and will use the Westin again!
  Jan 11, 2018

$118

$118
Hampton Inn and Suites Cincinnati Downtown

Hampton Inn and Suites Cincinnati Downtown

617 Vine Street, Cincinnati
3.0 out of 5.0
4.6 out of 5 (339 reviews)
Beautiful hotel, conveniently located Great location, beautiful facility, friendly and knowledgeable staff! Great stay.
  Jan 14, 2018

$125

$125
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

609 Walnut St, Cincinnati
5.0 out of 5.0
4.7 out of 5 (578 reviews)
Very interesting with the modern art all around. Very clean room! Only issue is... how cold it was in the room at night (realizing it was very seasonably cold for Cincinnati)! Thanks, We'll come again if we're back in Cincinnati, Jeff and Terri Johnson
  Jan 8, 2018

$127

$127
Cincinnatian Hotel

Cincinnatian Hotel

601 Vine Street, Cincinnati
4.5 out of 5.0
4.2 out of 5 (1,488 reviews)
Great rooms, but little elseI wasn't aware, until the day before arrival that the first two floors of the hotel were under construction. This meant that the lobby, bar, and restaurant were housed in very small, generic spaces. A look at the hotel atrium revealed a bad redesign in the past, which is, I assume, the reason for ...
  Jan 16, 2018

$143

$143
Hyatt Regency Cincinnati

Hyatt Regency Cincinnati

151 West Fifth Street, Cincinnati
4.0 out of 5.0
4.2 out of 5 (990 reviews)
Great location We came for the football the hotel was only 3 blocks from the stadium they were a friendly staff and gave us fast prompt service. I would stay at this hotel again
  Dec 29, 2017

$149

$149
Quality Inn & Suites Cincinnati Downtown

Quality Inn & Suites Cincinnati Downtown

800 W 8th St, Cincinnati
2.5 out of 5.0
3.3 out of 5 (317 reviews)
Nice hotel at a reasonable price I was pleasantly surprised at the quality of this Quality Inn. The price was reasonable and it is convenient to Uber to all downtown locations. The average fare was under $8. The room was quiet and extremely clean. The staff was friendly and helpful. Soon they will have a restaurant, in addition ...
  Jan 7, 2018

$75

$75
Residence Inn by Marriott Cincinnati Downtown/The Phelps

Residence Inn by Marriott Cincinnati Downtown/The Phelps

506 East 4th Street, Cincinnati
3.5 out of 5.0
4.9 out of 5 (254 reviews)
Nice hotel close to the Interstate and CasinoWE arrived at 11:00 p.m. after some delays driving and were checked in immediately. Staff was very friendly and helpful. The room was great, (also the breakfast in the morning!)
  Dec 6, 2017

$170

$170
Homewood Suites by Hilton Cincinnati-Downtown

Homewood Suites by Hilton Cincinnati-Downtown

617 Vine Street, Suite B, Cincinnati
3.5 out of 5.0
4.5 out of 5 (186 reviews)
Very comfortableMy room was large and comfortable with a small but well-equipped kitchen. Overall my stay was excellent but a couple of tips if you are planning to stay here: 1. The fridge can be quite loud, so if you are staying in a studio room with no walls between the kitchen and bedroom, you might need some ...
  Oct 8, 2017

$134

$134
Renaissance Cincinnati Downtown Hotel

Renaissance Cincinnati Downtown Hotel

36 East Fourth Street, Cincinnati
4.0 out of 5.0
4.6 out of 5 (453 reviews)
Nice hotel close to lots of things to doHad a very enjoyable stay. We had a few issues with the room upon check-in but staff responded immediately and went above and beyond making sure all was good. Even gave us a breakfast buffet coupon for the third person in our room (only two came with reservation) and a bottle of wine as we were there ...
  Dec 4, 2017

$160

$160
Holiday Inn Hotel & Suites Cincinnati Downtown

Holiday Inn Hotel & Suites Cincinnati Downtown

701 Broadway Street, Cincinnati
3.0 out of 5.0
4.4 out of 5 (45 reviews)
Excellent! As always the hotel and restaurant staff was beyond expectations. The service was excellent and the food extremely palette pleasing. We will definitely be back for every trip we have in this area.
  Dec 12, 2017

$148

$148
Map

Recently booked Business Hotels in Downtown Cincinnati

Cincinnatian Hotel
4.5 out of 5.0
Last booking: 1 hour ago
The Westin Cincinnati
4.0 out of 5.0
Last booking: 1 hour ago
Millennium Cincinnati
3.5 out of 5.0
Last booking: 3 hours ago
Homewood Suites by Hilton Cincinnati-Downtown
3.5 out of 5.0
Last booking: 4 hours ago
21c Museum Hotel Cincinnati
5.0 out of 5.0
Last booking: 9 hours ago
Renaissance Cincinnati Downtown Hotel
4.0 out of 5.0
Last booking: 14 hours ago
Residence Inn by Marriott Cincinnati Downtown/The Phelps
3.5 out of 5.0
Last booking: 14 hours ago
Hilton Cincinnati Netherland Plaza
4.5 out of 5.0
Last booking: 16 hours ago
Quality Inn & Suites Cincinnati Downtown
2.5 out of 5.0
Last booking: 17 hours ago

Pocket Guide: Business Hotels in Downtown Cincinnati

Search for hotels in Downtown Cincinnati on Expedia. You can easily find your hotels in Downtown Cincinnati using one of the methods below:

  • View our selection of featured hotels in Downtown Cincinnati
  • Use the map to find hotels in the Downtown Cincinnati neighborhood you prefer
  • Use the filters to see hotels in a specific area of Downtown Cincinnati, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Downtown Cincinnati
  • Enter your travel dates to view the best deals on hotels in Downtown Cincinnati - while they last