Beginning of main content

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Downtown Guadalajara Mision Hotels

See all 250 Hotels in Downtown Guadalajara
Hotel Misión Guadalajara Carlton

Hotel Misión Guadalajara Carlton

Ave Ninos Heroes 125, Guadalajara
3.5 out of 5.0
3.3 out of 5 (591 reviews)
Great experience It was a great experience but the room needed to be better clean - 

$40

$40

Recently booked Downtown Guadalajara hotels

Hotel Real Maestranza
4.0 out of 5.0
Last booking: 4 hours ago
Hotel Dali Ejecutivo
3.0 out of 5.0
Last booking: 6 hours ago
Holiday Inn Hotel & Suites Guadalajara-Centro Historico
4.0 out of 5.0
Last booking: 6 hours ago
One Guadalajara Centro Histórico
3.0 out of 5.0
Last booking: 7 hours ago
Hotel Casino Plaza
4.0 out of 5.0
Last booking: 7 hours ago
Hotel Nueva York
3.0 out of 5.0
Last booking: 10 hours ago
Hotel Morales Historical & Colonial Downtown Core
4.0 out of 5.0
Last booking: 14 hours ago
Real Inn Guadalajara Centro
3.0 out of 5.0
Last booking: 17 hours ago
Perla Central Hotel
4.0 out of 5.0
Last booking: 23 hours ago

Pocket Guide: Mision Hotels in Downtown Guadalajara

Search for hotels in Downtown Guadalajara on Expedia. You can easily find your hotels in Downtown Guadalajara using one of the methods below:

  • View our selection of featured hotels in Downtown Guadalajara
  • Use the map to find hotels in the Downtown Guadalajara neighborhood you prefer
  • Use the filters to see hotels in a specific area of Downtown Guadalajara, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Downtown Guadalajara
  • Enter your travel dates to view the best deals on hotels in Downtown Guadalajara - while they last