Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the best price available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Downtown Portland Business Hotels

See all 178 Hotels in Downtown Portland
The Westin Portland Harborview

The Westin Portland Harborview

157 High St, Portland
4.0 out of 5.0
4.3 out of 5 (847 reviews)
Cozy room Great bed, very soft and comfortable .clean bathroom with lots towels
  Nov 18, 2017

$119

$119
Holiday Inn Portland-By the Bay

Holiday Inn Portland-By the Bay

88 Spring St, Portland
3.0 out of 5.0
4.2 out of 5 (1,115 reviews)
Another good experience2nd stay here - enjoyable again. Very pleasant staff, very nice accommodations, decent price.
  Nov 22, 2017

$97

$97
Portland Regency Hotel & Spa

Portland Regency Hotel & Spa

20 Milk Street, Portland
3.5 out of 5.0
4.4 out of 5 (1,304 reviews)
Fabulous hotel in a wonderful locationThis is a wonderful hotel in an excellent part of Portland, close to shopping restaurants and the ferry. Staff were friendly and helpful and nothing was too much trouble. Rooms were large and comfortable and the service was great. The hotel provided coffee and tea pastries every morning and transfers ...
  Nov 22, 2017

$140

$140
Hampton Inn Portland Downtown Waterfront

Hampton Inn Portland Downtown Waterfront

209 Fore St, Portland
2.5 out of 5.0
4.5 out of 5 (889 reviews)
Three days for workConvenient location. Great staff. Parking is a big expensive. So...maybe avoid if you have a car / do research on other hotels.
  Nov 11, 2017

$107

$107
Hilton Garden Inn Portland Downtown Waterfront

Hilton Garden Inn Portland Downtown Waterfront

65 Commercial St, Portland
3.0 out of 5.0
4.6 out of 5 (759 reviews)
Great locationCame to Portland for an event at Cross Arena - this hotel is a great location for proximity to the arena and it is in old port so all the better!
  Nov 18, 2017

$114

$114
Hyatt Place Portland-Old Port

Hyatt Place Portland-Old Port

433 Fore St, Portland
3.0 out of 5.0
4.3 out of 5 (966 reviews)
Perfect locationGreat location. Nice staff. Breakfast was a nice addition.
  Nov 14, 2017

$108

$108
Courtyard Portland Downtown/Waterfront

Courtyard Portland Downtown/Waterfront

321 Commercial St, Portland
3.0 out of 5.0
4.5 out of 5 (404 reviews)
Nice hotel Everything Portland has to offer downtown within walking distance from hotel. Bam Bam bakery 1 block away. Great coffee and quick breakfast baked goods.
  Nov 12, 2017

$109

$109
Portland Harbor Hotel

Portland Harbor Hotel

468 Fore Street, Portland
4.0 out of 5.0
4.5 out of 5 (128 reviews)
Great LocationGreat place to stay, close/walking distance to venues such as the Cross Insurance Arena. The hotel concierge was very helpful, the staff was also very courteous and helpful.
  Nov 20, 2017

$118

$118
The Press Hotel, Marriott Autograph Collection

The Press Hotel, Marriott Autograph Collection

119 Exchange Street, Portland
4.0 out of 5.0
4.7 out of 5 (298 reviews)
Excellent Service, Rooms, UNION Restaurant located in the building, Excellent Hospitality, Proximity to downtown Portland. Will be returning in warmer months.
  Nov 14, 2017

$143

$143
Map

Recently booked Business Hotels in Downtown Portland

The Westin Portland Harborview
4.0 out of 5.0
Last booking: 3 hours ago
Courtyard Portland Downtown/Waterfront
3.0 out of 5.0
Last booking: 5 hours ago
Hilton Garden Inn Portland Downtown Waterfront
3.0 out of 5.0
Last booking: 11 hours ago
The Press Hotel, Marriott Autograph Collection
4.0 out of 5.0
Last booking: 14 hours ago
Portland Regency Hotel & Spa
3.5 out of 5.0
Last booking: 24 hours ago
Hyatt Place Portland-Old Port
3.0 out of 5.0
Last booking: 26 hours ago
Holiday Inn Portland-By the Bay
3.0 out of 5.0
Last booking: 29 hours ago
Hampton Inn Portland Downtown Waterfront
2.5 out of 5.0
Last booking: 40 hours ago

Pocket Guide: Business Hotels in Downtown Portland

Search for hotels in Downtown Portland on Expedia. You can easily find your hotels in Downtown Portland using one of the methods below:

  • View our selection of featured hotels in Downtown Portland
  • Use the map to find hotels in the Downtown Portland neighborhood you prefer
  • Use the filters to see hotels in a specific area of Downtown Portland, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Downtown Portland
  • Enter your travel dates to view the best deals on hotels in Downtown Portland - while they last