Find Business Hotels in Downtown San Diego, CA

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Check availability on Downtown San Diego Business Hotels

Tonight
Dec 7 - Dec 8
Tomorrow
Dec 8 - Dec 9
Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21

Top Downtown San Diego Business Hotels

Outdoor pool, sun loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1852)
"Enjoyed my stay"
United States
Brandon
$123 nightly
The price is $143
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hilton San Diego Bayfront
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2871)
"It was nice and the bar up top was great"
United States
Brent
$223 nightly
The price is $259
Dec 14 - Dec 15
Total with taxes and fees
Manchester Grand Hyatt San Diego
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillowtop beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (718)
"Great staff, great location, great value. "
United States
Juan
$103 nightly
The price is $120
Dec 15 - Dec 16
Total with taxes and fees
The DEXTRO Little Italy, BW Premier Collection
Lobby
Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1181)
"Amazing stay "
United States
Aaron
$168 nightly
The price is $194
Dec 22 - Dec 23
Total with taxes and fees
Hotel Republic San Diego, Autograph Collection
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1939)
"Great hotel"
United States
Farzana
$204 nightly
The price is $237
Dec 18 - Dec 19
Total with taxes and fees
Marriott Marquis San Diego Marina
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1050)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
$160 nightly
The price is $186
Dec 19 - Dec 20
Total with taxes and fees
The Westin San Diego Bayview
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6073)
"Always an amazing stay"
United States
Jana
$160 nightly
The price is $186
Dec 10 - Dec 11
Total with taxes and fees
Wyndham San Diego Bayside
Exterior
San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1589)
"All was very nice!"
United States
Tim
$144 nightly
The price is $167
Dec 14 - Dec 15
Total with taxes and fees
San Diego Marriott Gaslamp Quarter
Lobby sitting area
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2043)
"It was an amazing stay "
United States
Alejandra
$225 nightly
The price is $261
Jan 4 - Jan 5, 2026
Total with taxes and fees
Omni San Diego Hotel at the Ballpark
Outdoor pool, pool umbrellas, sun loungers
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

2.5 star property
Downtown San Diego
8.2 out of 10, Very Good, (2268)
"Great stay, I recommend it"
United States
Furio
$104 nightly
The price is $120
Dec 21 - Dec 22
Total with taxes and fees
Hampton Inn San Diego-Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Price trends for hotels in Downtown San Diego

Less expensive
More expensive
This month
Next month
December
November
$130
$182
Month
Price
January
$182
February
$216
March
$226
April
$250
May
$247
June
$304
July
$307
August
$273
September
$303
October
$339
November
$340
December
$130
Price trend information excludes taxes and fees and is based on base rates for a nightly stay for 2 adults found in the last 7 days on our site and averaged for commonly viewed hotels in Downtown San Diego. Select dates and complete search for nightly totals inclusive of taxes and fees.

Top Downtown San Diego Hotel Reviews

The Westin San Diego Bayview

The Westin San Diego Bayview

10/10 Excellent
"The staff was friendly. "
Alba 2-night trip
Posted 1 day ago
The Westin San Diego Bayview

Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
Expedia is here to help you find a fantastic business-friendly hotel when work takes you out of town. From free parking and WiFi to on-site restaurants and cafés, our stays come with all you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Downtown San Diego?
Expedia can help you easily find cheap business-friendly hotels in Downtown San Diego. Head to our "traveler experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work and rest comfortably, like free WiFi and included breakfast. You can also choose your budget and hotel star rating to keep costs down.

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