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Featured Downtown San Francisco Independent Hotels

See all 176 Hotels in Downtown San Francisco
Hotel Spero

Hotel Spero

405 Taylor St, San Francisco
    4.0 out of 5.0
     
     
    4.0 out of 5 (4,722 reviews)
    Two thumbs up The hotel was very nicely designed. I had a queen suite; it was a cozy. You can tell it’s been newl … - 

    Hotel Spero$136

    Hotel Spero$136
    Hotel Whitcomb

    Hotel Whitcomb

    1231 Market St, San Francisco
      3.5 out of 5.0
       
       
      3.2 out of 5 (8,604 reviews)
      Hotel is old and dated. Very thin walls. No coffee machine in room. A bottle of water would have be … - 

      Hotel Whitcomb$119

      Hotel Whitcomb$119
      Chancellor Hotel on Union Square

      Chancellor Hotel on Union Square

      433 Powell St, San Francisco
        3.5 out of 5.0
         
         
        4.3 out of 5 (3,711 reviews)
        Nice Boutique Hotel Near Everything My husband and I stayed at the Chancellor for 4 nights. The hotel staff was very helpful and friend … - 

        Chancellor Hotel on Union Square$161

        Chancellor Hotel on Union Square$161
        Handlery Union Square Hotel

        Handlery Union Square Hotel

        351 Geary St, San Francisco
          3.5 out of 5.0
           
           
          4.0 out of 5 (4,278 reviews)
          Great place to stay I was pleased with the room, staff was nice. It was a bit warm, as the thermostat only goes to 65. … - 

          Handlery Union Square Hotel$149

          Handlery Union Square Hotel$149
          The Pickwick Hotel

          The Pickwick Hotel

          85 5th St, San Francisco
            3.5 out of 5.0
             
             
            3.5 out of 5 (1,932 reviews)
            They had Friendly staff. It was a great location near museums, a large mall, and bars. - 

            The Pickwick Hotel$159

            The Pickwick Hotel$159
            Hotel Vertigo

            Hotel Vertigo

            940 Sutter Street, San Francisco
              3.5 out of 5.0
               
               
              4.0 out of 5 (1,496 reviews)
              Close to everything The hotel is great close to everything friendly staff - 

              Hotel Vertigo$197

              Hotel Vertigo$197
              Mystic Hotel

              Mystic Hotel

              417 Stockton St, San Francisco
                3.5 out of 5.0
                 
                 
                4.0 out of 5 (2,473 reviews)
                Nice hotel. Small but big for San Fran. It’s bigger by a few square feet than some other nearby comperable union square hotel rooms. 1 min … - 

                Mystic Hotel$155

                Mystic Hotel$155
                Monarch Hotel

                Monarch Hotel

                1015 Geary St, San Francisco
                  2.0 out of 5.0
                   
                   
                  3.0 out of 5 (1,950 reviews)
                  Perfect location. Love staying here. Staff is so nice. We always stay here - 
                  Grant Plaza Hotel

                  Grant Plaza Hotel

                  465 Grant Ave, San Francisco
                    2.0 out of 5.0
                     
                     
                    3.2 out of 5 (2,088 reviews)
                    Great location. Rooms are small but clean. Overall good experience - 
                    Grant Hotel

                    Grant Hotel

                    753 Bush St, San Francisco
                      2.0 out of 5.0
                       
                       
                      3.6 out of 5 (2,804 reviews)
                      Simple, clean, affordable Perfect for my one night stay. Small hotel with basic needs covered. Very clean. Coffee in lobby an … - 
                      Axiom Hotel San Francisco

                      Axiom Hotel San Francisco

                      28 Cyril Magnin Street, San Francisco
                        4.0 out of 5.0
                         
                         
                        4.4 out of 5 (677 reviews)
                        Great stay No complaints about Hotel Axiom. I’m a very light sleeper so we requested a quiet room and had zero … - 
                        The Mosser

                        The Mosser

                        54 4th Street, San Francisco
                          2.5 out of 5.0
                           
                           
                          3.9 out of 5 (4,448 reviews)
                          Enjoyable stsy My stay was enjoyable. However there were a few episodes of cigarette smoke coming into my room, an … - 
                          Adante Hotel, a C-Two Hotel

                          Adante Hotel, a C-Two Hotel

                          610 Geary St, San Francisco
                             
                             
                            3.2 out of 5 (1,973 reviews)
                            Budget friendly hotel in San Francisco Overall the hotel was a good deal for the price in an accessible/convenient part of the city. The r … - 

                            Adante Hotel, a C-Two Hotel$139

                            Adante Hotel, a C-Two Hotel$139
                            Hotel G San Francisco

                            Hotel G San Francisco

                            386 Geary Street, San Francisco
                              4.0 out of 5.0
                               
                               
                              4.1 out of 5 (1,347 reviews)
                              convenient good location bath light would not work resetting the gfi would fix for 5 minutes but who goes to sf to be in bat … - 
                              Calista Organic Hotel

                              Calista Organic Hotel

                              1485 Bush Street, San Francisco
                                3.0 out of 5.0
                                 
                                 
                                3.6 out of 5 (231 reviews)
                                Nice Hotel, Great Central Location, Friendly Staff For the price you pay, this hotel is great. It's located in the middle of SF with many tourist attr … - 

                                Calista Organic Hotel$137

                                Calista Organic Hotel$137
                                Hotel Metropolis

                                Hotel Metropolis

                                25 Mason Street, San Francisco
                                  3.0 out of 5.0
                                   
                                   
                                  3.3 out of 5 (1,676 reviews)
                                  Easy check in. Polite staff. Great area for walking. - 
                                  King George Hotel - A Greystone Hotel

                                  King George Hotel - A Greystone Hotel

                                  334 Mason Street, San Francisco
                                    3.0 out of 5.0
                                     
                                     
                                    3.8 out of 5 (2,194 reviews)
                                    Nice hotel! We only stayed one night, as planned. The location was perfect for us. The room was very nice and c … - 

                                    King George Hotel - A Greystone Hotel$120

                                    King George Hotel - A Greystone Hotel$120
                                    Tilden Hotel

                                    Tilden Hotel

                                    345 Taylor St, San Francisco
                                      4.0 out of 5.0
                                       
                                       
                                      3.4 out of 5 (313 reviews)
                                      Good for price An old, tired building that has been reasonably well decorated. Room wasn’t perfectly clean (old co … - 
                                      The Andrews Hotel

                                      The Andrews Hotel

                                      624 Post St, San Francisco
                                        3.0 out of 5.0
                                         
                                         
                                        3.8 out of 5 (1,437 reviews)
                                        Lovely little hotel - clean and well situated with great staff. I also appreciated the nice 'extras … - 

                                        The Andrews Hotel$149

                                        The Andrews Hotel$149
                                        Cornell Hotel de France

                                        Cornell Hotel de France

                                        715 Bush St, San Francisco
                                          3.5 out of 5.0
                                           
                                           
                                          4.2 out of 5 (1,011 reviews)
                                          Great value and style Cozy, centrally located and great value for the money. I would recommend. - 
                                          Map

                                          Recently booked Downtown San Francisco hotels

                                          Hotel Whitcomb
                                          3.5 out of 5.0
                                          Last booking: 9 minutes ago
                                          The Bartlett Hotel and Guesthouse
                                          2.5 out of 5.0
                                          Last booking: 12 minutes ago
                                          The Pickwick Hotel
                                          3.5 out of 5.0
                                          Last booking: 20 minutes ago
                                          Tilden Hotel
                                          4.0 out of 5.0
                                          Last booking: 23 minutes ago
                                          Hotel Nikko San Francisco
                                          4.0 out of 5.0
                                          Last booking: 24 minutes ago
                                          Hotel Spero
                                          4.0 out of 5.0
                                          Last booking: 24 minutes ago
                                          Hotel Rex San Francisco
                                          3.5 out of 5.0
                                          Last booking: 29 minutes ago
                                          The Andrews Hotel
                                          3.0 out of 5.0
                                          Last booking: 41 minutes ago
                                          Hilton San Francisco Union Square
                                          4.0 out of 5.0
                                          Last booking: 50 minutes ago

                                          Independent Downtown San Francisco Hotel Guide

                                          Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Downtown San Francisco, San Francisco. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Downtown San Francisco hotels guarantees an unparalleled level of comfort and quality.

                                          You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Downtown San Francisco Independent locations may even offer extra little benefits and discounts for frequent travelers.