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Downtown San Francisco, CA Luxury Hotels $158

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Downtown San Francisco Hotels

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Top Downtown San Francisco Neighborhoods for Luxury Hotels

Union Square
73 hotels
from

$299

South of Market
22 hotels
from

$170

Featured Downtown San Francisco Luxury Hotels

See all 177 Hotels in Downtown San Francisco
Taj Campton Place

Taj Campton Place

340 Stockton St, San Francisco
4.5 out of 5.0
4.6 out of 5 (425 reviews)
Great hotel in a perfect location!Fabulous staff. Upgraded our room. Fabulous restaurant and bar! Best breakfast in town!
  Jul 22, 2017

$300

$300
The Westin St Francis San Francisco on Union Square

The Westin St Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.1 out of 5 (1,770 reviews)
Great location to stay when visiting San FranciscoExcellent location to take in all the sites in San Francisco. Easy access from SFO on the BART or a shuttle. Lots of shopping and restaurants nearby. Sight seeing buses and cable car access right out front the hotel. Only a 40 minute walk to Fisherman's Wharf too.
  Aug 17, 2017

$195

$195
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

757 Market St, San Francisco
5.0 out of 5.0
4.5 out of 5 (199 reviews)
The hotel is clean- staff is professional- food is great- rooms are very nice and comfortable.
  Aug 7, 2017

$400

$400
The St. Regis San Francisco

The St. Regis San Francisco

125 3rd St, San Francisco
5.0 out of 5.0
4.7 out of 5 (96 reviews)
Great hotel with great service Stayed here with my family (wife and 2 kids). The room was big by normal hotel standards and huge for SF. Staff was great and made us feel welcomed at all times. Sent kid sized robes for our kids to use (which they loved) and a dessert and card for my wife to celebrate her birthday. Kids also got ...
  Aug 2, 2017

$399

$399
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
4.5 out of 5.0
4.6 out of 5 (570 reviews)
Convenient+locationOur+stay+at+the+Scarlet+Huntington+was+just+the+thing+we+needed+after+a+weekend+at+Outside+Lands+music+festival.+The+hotel+provided+the+relaxation+we+so+craved+after+a+weekend+of+non-stop+going.+
  Aug 17, 2017

$229

$229
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.4 out of 5 (2,006 reviews)
Iconic but...No hot water - maintenance during peak bathing. Couldn't they wait until after 9am to begin???
  Aug 17, 2017

$299

$299
Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco
4.0 out of 5.0
3.9 out of 5 (1,558 reviews)
close+to+everythingdelightful+old+world+style+hotel+-+authentic+posh+city+experience
  Aug 17, 2017

$158

$158
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
4.5 out of 5.0
4.4 out of 5 (879 reviews)
Nice+clean+hotel+close+to+union+squareThe+staff+was+very+helpful+and+friendly.%0D%0ARoom+was+nice+and+clean.+We+would+stay+again+
  Aug 17, 2017

$170

$170
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (1,496 reviews)
True+five+star+hotel+with+the+quality+expected+from+the+quality+of+the+room+and+services
  Aug 17, 2017

$265

$265
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (398 reviews)
A terrific location and wonderful hotel, our family enjoyed everything the Ritz had to offer.
  Jul 31, 2017

$379

$379
Map

Recently booked Luxury Hotels in Downtown San Francisco

Hilton San Francisco Union Square
4.0 out of 5.0
Last booking: 8 minutes ago
Monarch Hotel
2.0 out of 5.0
Last booking: 8 minutes ago
Regency Inn
2.0 out of 5.0
Last booking: 15 minutes ago
Fairmont San Francisco
5.0 out of 5.0
Last booking: 20 minutes ago
Adante Hotel, a C-Two Hotel
2.0 out of 5.0
Last booking: 23 minutes ago
San Francisco Marriott Union Square
4.0 out of 5.0
Last booking: 25 minutes ago
Clift
4.0 out of 5.0
Last booking: 27 minutes ago
The Scarlet Huntington Hotel
4.5 out of 5.0
Last booking: 27 minutes ago
The Marker San Francisco, a Joie de Vivre Hotel
4.0 out of 5.0
Last booking: 35 minutes ago

A weekend away keeps your worries at bay, and Downtown San Francisco is the perfect place to visit. Intriguing attractions, divine eats, and chances to capture terrific photos: these are just a few of the things you'll discover in Downtown San Francisco. You'll devour delicious food, marvel at the best attractions in the region, and enjoy the most sought-after shows. Of course, you'll stay at a luxury hotel! Extravagant experiences are right up your alley, so reserve your luxury hotel in Downtown San Francisco on Expedia.com today, and your relaxing getaway is off to a great start.

5-Star Vacations in Downtown San Francisco

It turns out plenty of folks love Downtown San Francisco enough to live here -- how is that for proof that Downtown San Francisco is full of an incredible array of activities? No matter what brings you to Downtown San Francisco, the destination always delivers. Downtown San Francisco is full of great hotels in addition to friendly locals, so you can count on a spectacular stay. Book well in advance to get the best room!

Any 5-star getaway is the perfect opportunity to indulge in art, culture, and spa treatments. When you save big by booking on Expedia.com, you never have to limit yourself. Thanks to our unbeatable rates on hotels, you can always afford to experience the city's most exciting points of interest. After a day of adventure, your luxury hotel is waiting with spectacular food and impressive amenities. Take advantage of amenities like an incredible balcony view or indoor pool before the day is through. The luxury accommodations in Downtown San Francisco will soothe you into a state of tranquility before you know it.

Find Luxury Downtown San Francisco Hotels Now

It's that time; you're prepared to get swept away in Downtown San Francisco, and Expedia.com is here to save the day. Search through the bounty of real traveler reviews on incredible hotels until you find the right one. 5-Star hotels treat you right, offering things like VIP services and private kitchens. Some of the city's luxe accommodations even feature impeccable penthouses, while others offer tennis courts or salt water pools. Use our mobile booking app to choose a fabulous 5-star hotel in Downtown San Francisco, and soon you'll be soaking up luxury in style!