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Top Downtown San Francisco Neighborhoods for Resorts & Hotels with Spas

Union Square
1 hotels
from

$195

South of Market
52 hotels
from

$143

Featured Downtown San Francisco Resorts & Hotels with Spas

See all 183 Hotels in Downtown San Francisco
The Scarlet Huntington Hotel

The Scarlet Huntington Hotel

1075 California St, San Francisco
4.5 out of 5.0
4.6 out of 5 (1,569 reviews)
Elegant hotel and luxurious spaThird stay at the Huntington. The ambience, amenities, location, food and service are top notch. Love the boutique hotel feel. Views are amazing.
 Julie Nov 4, 2014

$195

$195
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco
4.0 out of 5.0
4.3 out of 5 (6,469 reviews)
My Favorite Union Square HotelGreat fitness and spa, nice rooms, decent views and super-friendly staff.
  Feb 15, 2016

$176

$176
InterContinental San Francisco

InterContinental San Francisco

888 Howard Street, San Francisco
4.5 out of 5.0
4.5 out of 5 (2,841 reviews)
Enjoyable stay, friendly staff, great locationMy husband, nine-year-old son and I were at the Intercontinental for a recent "staycation" and completely enjoyed our weekend there. The room was very comfortable; every single staff person was helpful and friendly; and the pool, fitness room and spa made it a perfect stay.
  Dec 8, 2014

$143

$143
The Marker San Francisco, a Joie de Vivre Hotel

The Marker San Francisco, a Joie de Vivre Hotel

501 Geary St, San Francisco
4.0 out of 5.0
4.4 out of 5 (2,184 reviews)
Happy Birthday to my husbandI wanted something a bit special for his 60th Birthday. Although the hotel did not do any thing special. The room was wonderful we enjoyed the spa and the restaurant was exceptional!
 clarice Jul 30, 2016

$159

$159
Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel

55 Cyril Magnin St, San Francisco
4.0 out of 5.0
4.2 out of 5 (11,419 reviews)
Friendly atmosphereVery large, inviting hotel. Concierge extremely knowledgable and friendly. Only downside - no spa in the hotel.
  Nov 29, 2014

$135

$135
Palace Hotel, a Luxury Collection Hotel, San Francisco

Palace Hotel, a Luxury Collection Hotel, San Francisco

2 New Montgomery St, San Francisco
5.0 out of 5.0
4.5 out of 5 (3,577 reviews)
Excellent location, very friendly staffNice indoor pool and sauna. The hotel staff greeted us with chocolates at check in. The lobby is beautiful.
  Mar 30, 2014

$191

$191
The Westin St. Francis San Francisco on Union Square

The Westin St. Francis San Francisco on Union Square

335 Powell Street, San Francisco
4.0 out of 5.0
4.2 out of 5 (5,221 reviews)
St Francis Westin Hotel is magnificentFantastic guest services, phenomenal bar downstairs (The Clock Bar), and terific gym and spa. Definitely my favorite hotel in the states.
  Jan 23, 2014

$158

$158
San Francisco Marriott Marquis

San Francisco Marriott Marquis

780 Mission Street, San Francisco
4.0 out of 5.0
4.3 out of 5 (4,483 reviews)
Nice hotel centrally locatedWhen my family decided to take a quick getaway weekend to San Francisco we wanted to find somewhere close to shopping and resturants with spa services and a fitness center. After staying at the Marriot Marquis we came very satisfied. Not only is it right near union scquare and city center but the ...
 jose Feb 17, 2014

$169

$169
Four Seasons Hotel San Francisco

Four Seasons Hotel San Francisco

757 Market St, San Francisco
5.0 out of 5.0
4.5 out of 5 (469 reviews)
Need renovation / Spa awfulThe hotel needs to be renovated. The spa is inside an open to the public gym and it is in awful conditions
  May 12, 2016

$415

$415
The St. Regis San Francisco

The St. Regis San Francisco

125 3rd St, San Francisco
5.0 out of 5.0
4.7 out of 5 (292 reviews)
Confortable hotel close to shopping & dining optioThe St Regis is a comfortable hotel, centrally located with helpful staff. I booked a Grand Deluxe room - while comfortable it was not very spacious - I can only think if I had booked a regular or even a Delux room I'd have been disappointed with the room. The room furnishings were plush and comfortable ...
 PC Jun 9, 2014

$395

$395
Hilton San Francisco Union Square

Hilton San Francisco Union Square

333 O'Farrell St., San Francisco
4.0 out of 5.0
4.0 out of 5 (8,367 reviews)
Central location. Luxurious facility with poolWonderful location near trolley cars and BART and muni station. Great staff, beautiful rooms, nice pool and sauna. Well equipped gym!.
 Smokey Aug 24, 2017

$135

$135
Fairmont San Francisco

Fairmont San Francisco

950 Mason Street Atop Nob Hill, San Francisco
5.0 out of 5.0
4.5 out of 5 (4,923 reviews)
Nice hotel and centrally locatedI was greeted with a great smile, loved the accommodations and the spa and staff was great.
 matt G Oct 2, 2015

$199

$199
W San Francisco

W San Francisco

181 3rd St, San Francisco
4.0 out of 5.0
4.2 out of 5 (1,305 reviews)
Birthday GetawayThis hotel is great . It's located downtown , with lots walking distance and the restaurant, bar and club are located in the lobby. There is also a Bliss Spa located inside the hotel which iI enjoyed. Only complaint is the AC.. barely works. Other than that I will revis this hotel again. And let's ...
 Blanchee Sep 11, 2017

$199

$199
The Ritz-Carlton, San Francisco

The Ritz-Carlton, San Francisco

600 Stockton St, San Francisco
5.0 out of 5.0
4.5 out of 5 (767 reviews)
Great location on historic Nob hillChef had a wonderful tasting menu. Great pet friendly hotel. Everyone from the doormen to the spa personnel were really friendly and professional.
 Adam Apr 9, 2014

$332

$332
The Donatello Hotel

The Donatello Hotel

501 Post St, San Francisco
3.5 out of 5.0
4.4 out of 5 (1,695 reviews)
Spacious, well-located 2 night stayWe found the room to be, for four of us (two adults, two teens) to be spacious and comfortable. There was enough room to spread out, and the fact that we had a microwave, fridge and all basic kitchen supplies (even including a bottle opener) was super. Included in our rate we had access to the Club ...
  Jun 16, 2016

$118

$118
Hotel Rex San Francisco

Hotel Rex San Francisco

562 Sutter St, San Francisco
3.5 out of 5.0
4.2 out of 5 (1,619 reviews)
Great hotel, perfect location!After missing our flight, hotel Rex was so accommodating! Enjoyed our short stay, loved the Library Bar, & walked out the door into beautiful San Francisco Union Square!
  Nov 18, 2017

$125

$125
Marriott Courtyard San Francisco Downtown

Marriott Courtyard San Francisco Downtown

299 2nd St, San Francisco
3.5 out of 5.0
4.3 out of 5 (1,890 reviews)
Good location nice breakfast & pool costly parkingOverall nice hotel in quiet area (2nd street). Walking distance 5-10minutes to Union square, cable-car, F-line, and BART. There's a good choice of restaurants on the same street, ranging from a Subway and Meditterranean to Indian and Thai food. Kid friendly. Hotel staff is very friendly.Room was ...
 Michael Apr 7, 2014

$143

$143
Clift

Clift

495 Geary St, San Francisco
4.0 out of 5.0
4.1 out of 5 (3,916 reviews)
Perfect location to all my tech events Excellent location. Staff was super friendly. Breakfast in the velvet room was incredible. Stayed here at the recommendation of a friend. Will certainly stay again.
  Nov 22, 2017

$159

$159
Club Donatello

Club Donatello

441 Mason Street, San Francisco
4.1 out of 5 (14 reviews)
Great hotel and locationGreat location to everything, we could walk to everything. Staff were very helpful with local knowledge and directions. Would definitely stay there again, loved it.
  Nov 16, 2015
Map

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Downtown San Francisco Resorts & Spa Travel Guide

Pamper Yourself with a Spa Day in Downtown San Francisco

You deserve the royal treatment every now and then. Take the opportunity for a trip where you can have all your worries melt away in Downtown San Francisco. If you are seeking for extravagant accommodations or reasonable choices, we can assist you in finding the ideal place to stay. Pack up your bag and not your worries to begin your pressure-free vacation.

Book a Downtown San Francisco Spa Vacation that Won't Break the Bank

Make sure to take your time once you've checked-in. You've just begun your vacation, so spend a little time getting acquainted with your room. Decompress and stretch out for a bit. After that you can make your first appointment to indulge yourself at a nearby spa. After you've indulged yourself by getting a massage treatment, unwinding within the steam room, or soaking in the whirlpool, you can put on your explorer's hat and uncover the hidden gems of Downtown San Francisco. Discovering incredible foods, eclectic boutiques, or a happening venue can be one of the many highlights of your holiday. If you're not sure where to begin, check with your hotel's concierge attendant to get an idea for what Downtown San Francisco has to offer. There is no better source than a local to point you to an exciting evening out or to a cafe to sip a few drinks at and socialize. No matter what you decide to do, just be sure to hang loose. Your spa holiday shouldn't be anything but extremely relaxing.

When you are ready to find the best hotel in Downtown San Francisco for your spa getaway, book through Expedia and dream of all the ways you are going to relax.