Top 10 Hotels in Downtown San Francisco

See all 170 Hotels in Downtown San Francisco
Hotel Nikko San Francisco

Hotel Nikko San Francisco

222 Mason St, San Francisco 94102

4.5 out of 5.0
4.3 out of 5 (6,452 reviews)

The Asian-inspired Hotel Nikko San Francisco is located downtown, a 4-minute walk from Union Square and the designer shops of …

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Serrano Hotel

Serrano Hotel

405 Taylor St, San Francisco 94102

4.5 out of 5.0
4 out of 5 (4,434 reviews)

The Serrano Hotel is steps away from Union Square, perfectly positioned in the Theater District of San Francisco, 2 blocks …

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Handlery Union Square Hotel

Handlery Union Square Hotel

351 Geary St, San Francisco 94102

4.0 out of 5.0
4 out of 5 (4,747 reviews)

A half-block from cable cars, this hotel is 2 blocks from Westfield San Francisco Shopping Centre; the Moscone Center and the …

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Loews Regency San Francisco

Loews Regency San Francisco

222 Sansome St, San Francisco 94104

5.0 out of 5.0
4.6 out of 5 (369 reviews)

Offering spectacular views, this luxury hotel occupies the top floors of a 48-story tower in San Francisco's Financial …

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Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

424 Clay St, San Francisco 94111

4.0 out of 5.0
4.2 out of 5 (5,077 reviews)

Club Quarters Hotel in San Francisco is located in the center of the financial district, across from the Embarcadero Center …

$98
The Adrian

The Adrian

493 Eddy St, San Francisco 94109

2.5 out of 5.0

Located in Downtown San Francisco, this hotel is within a 10-minute walk of Asian Art Museum of San Francisco and Westfield …

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Harbor Court Hotel

Harbor Court Hotel

165 Steuart St, San Francisco 94105

4.0 out of 5.0
4.3 out of 5 (1,896 reviews)

Located in Downtown San Francisco, this romantic hotel is within a 15-minute walk of Ferry Building and Exploratorium. …

$109
Hotel Diva

Hotel Diva

440 Geary St, San Francisco 94102

4.0 out of 5.0
3.9 out of 5 (2,764 reviews)

This downtown San Francisco hotel is surrounded by shopping, restaurants and theaters, only 2 blocks from Union Square, and …

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Axiom Hotel San Francisco

Axiom Hotel San Francisco

28 Cyril Magnin Street, San Francisco 94102

4.0 out of 5.0
4.4 out of 5 (535 reviews)

Located in Downtown San Francisco, this hotel is within a 15-minute walk of Westfield San Francisco Centre, San Francisco …

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Villa Florence San Francisco on Union Square

Villa Florence San Francisco on Union Square

225 Powell St, San Francisco 94102

4.5 out of 5.0
4 out of 5 (3,480 reviews)

Infused with the spirit of Italy, this romantic downtown San Francisco retreat is on the Powell Street cable car line, less …

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Recent Reviews in Downtown San Francisco

Where to stay in Downtown San Francisco

Downtown San Francisco Hotel Guide

Top Downtown San Francisco Accommodations

San Francisco is an important city in United States of America. It has a number of interesting neighborhoods, including Downtown San Francisco, which is about 0.5 miles to the southeast of downtown San Francisco.

The Golden Gate Bridge, the University of San Francisco and Pier 39 are just a small sample of the star attractions that are worth visiting while staying in San Francisco.

Conveniently located near California College of the Arts is The St. Regis San Francisco and Loews Regency San Francisco, while the Fairmont Heritage Place, Ghirardelli Square and Four Seasons Hotel San Francisco are near the Powell St Cable Car Turnaround.

There are a range of places to stay available in Downtown San Francisco, which gives tourists the chance to contrast prices and facilities. Establishments at the more economical end of the scale include the Layne Hotel and Castle Inn.

Downtown San Francisco also has some more upscale accommodations, such as The Ritz-Carlton, San Francisco and JW Marriott San Francisco Union Square.

Accommodation options near Downtown San Francisco

If Downtown San Francisco accommodation doesn't suit, a good alternative is to check out the hotels in South of Market. Another alternative is to book a hotel in San Francisco, which is another San Francisco neighborhood.

To get the most out of your San Francisco vacation, be sure to check out Expedia's San Francisco vacation travel guide; for great places to stay, go to our San Francisco hotels page.

If you aren't that keen on embarking on a trek to visit, look into the nearby Fairmont San Francisco and The Scarlet Huntington Hotel. The San Francisco Marriott Union Square and Wyndham Canterbury at San Francisco are conveniently located options for accommodation, as visiting this attraction is a priority!

After a morning of wandering around Downtown San Francisco, make your way to The Creamery for a cup of coffee and an indulgent treat. When something heartier is in order, try San Francisco Marriott Marquis for a satisfying lunch. Finish another wonderful day at Comstock Saloon, a fun venue where locals get together for a night out.