Downtown Santo Domingo Vacations from $397

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Your Downtown Santo Domingo Vacation

Reserving a tailor-made Downtown Santo Domingo vacation package is an excellent way to know the ins and outs of this unique neighborhood. From its well-known places to its lesser-known treasures, you'll be sure to uncover something new. Start your trip to Downtown Santo Domingo by checking out nearby attractions such as Centro Olimpico, Quisqueya Stadium and Cathedral of Santo Domingo. No matter what your ideal Downtown Santo Domingo vacation looks like, you can turn it into reality with Expedia.

The Latest Downtown Santo Domingo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Altos de Caño Hondo
Coral Costa Caribe Beach Resort - All Inclusive
Nizao Beach Lodge
Bahia Principe Grand La Romana - All Inclusive
Hacienda Samana Bay Hotel & Residence

Where to stay in Downtown Santo Domingo

Find the best Downtown Santo Domingo areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Santo Domingo

Downtown Santo Domingo Hotel Deals

Embassy Suites by Hilton Santo Domingo

Embassy Suites by Hilton Santo Domingo

4 out of 5
Ave. Tiradentes #32, Corner of Gustavo Mejia, Santo Domingo
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $189 total per night from Aug 31 to Sep 1
$189 total
Aug 31 - Sep 1
Total with taxes and fees
9.2/10 Wonderful! (1,005 reviews)
"The hotel is located in a privileged neighborhood, good for shopping, good restaurants . The staff is very friendly, the rooms are comfortable and it is very clean. The food is delicious!!! I visit Santo Domingo 3-4 times a year and I stay in this hotel because of its convenience and and good ..."

Reviewed on Aug 19, 2025

Embassy Suites by Hilton Santo Domingo
Santo Domingo Marriott Hotel Piantini - New Hotel

Santo Domingo Marriott Hotel Piantini - New Hotel

4.5 out of 5
Av Abraham Lincoln esquina, Andres Julio Aybar Piantini, Santo Domingo
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $163 total per night from Sep 5 to Sep 6
$163 total
Sep 5 - Sep 6
Total with taxes and fees
9.4/10 Exceptional! (194 reviews)
"we enjoyed our two week vacation at the marriott bonvoy piantini. the hotel is beautiful and the staff is fantastic. will be back for sure."

Reviewed on Aug 19, 2025

Santo Domingo Marriott Hotel Piantini - New Hotel
Aloft Santo Domingo Piantini

Aloft Santo Domingo Piantini

4 out of 5
AV ABRAHAM LINCOLN ESQUINA, ANDRES JULIO AYBAR, Santo Domingo
Fully refundableReserve now, pay when you stay
$114 nightly
The price is $146 total per night from Aug 29 to Aug 30
$146 total
Aug 29 - Aug 30
Total with taxes and fees
9.4/10 Exceptional! (353 reviews)
"Good"

Reviewed on Aug 23, 2025

Aloft Santo Domingo Piantini
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Downtown Santo Domingo

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.