Title: Best East Prairie, MO Lodge Rentals from $54 | Expedia.com [East Prairie Travel Guide](https://expedia.com/East-Prairie.dx3000349349)[Hotels in East Prairie](https://expedia.com/East-Prairie-Hotels.d3000349349.Travel-Guide-Hotels)[Vacation Rentals in East Prairie](https://expedia.com/East-Prairie-Vacation-Rentals.d3000349349.Travel-Guide-VacationRentals)[Car Rentals in East Prairie](https://expedia.com/Car-Rentals-In-East-Prairie.d3000349349.Car-Rental-Guide)[East Prairie Vacation Packages](https://expedia.com/East-Prairie.d3000349349.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-02-27&endDate=2026-03-01&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-03-06&endDate=2026-03-08&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=3000349349&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=LODGE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) No exact matches found, but these alternatives could be just right ## Recommended hotels in East Prairie ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/85184a8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/f90ef358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/978331d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Sikeston, MO [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) Sikeston 9.4/10 Exceptional (1,004 reviews) "As always it was a perfect visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $94 nightly $108 total Feb 26 - Feb 27 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/f2cf9c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/c790aa73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/7d2010d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247451/27c728aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Sikeston [](https://www.expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) Sikeston 9.4/10 Exceptional (59 reviews) "Clean rooms great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) IRA $101 nightly $114 total Feb 28 - Mar 1 Total with taxes and fees [](https://www.expedia.com/Fairfield-By-Marriott-Inn-Suites-Sikeston.h111247451.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/e89ec295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/55808580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/57e73ffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn at Discovery Park of America [](https://www.expedia.com/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information) Union City 9.2/10 Wonderful (350 reviews) "The rooms are big and the property is spotless!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) debbie $71 nightly $84 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/77525d07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/4abadc7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/432f7137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Sikeston [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) Sikeston 9.0/10 Wonderful (483 reviews) "Very Clean room, friendly staff, breakfast in the morning. Will be staying again! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Affinity $95 nightly $108 total Feb 28 - Mar 1 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/5b4d84d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/ef46b494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/7d06bc03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108420000/108416700/108416635/0acd5e5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 By Wyndham Marston [](https://www.expedia.com/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) Marston 8.0/10 Very Good (48 reviews) "Room clean bed comfortable, breakfast simple but good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $67 nightly $76 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Marston-Hotels-Super-8-By-Wyndham-Marston.h108416635.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/08c2ace2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/a42cb957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/cf3c3f57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20594/9e3a2899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverstone Hotel Charleston-Sikeston [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) Charleston 6.8/10 (408 reviews) "The staff was very friendly and accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arturo $70 nightly $78 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Charleston-Hotels-The-Riverstone-Hotel.h20594.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/7bc13d14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/7397c7ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/d5184d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible, Non Smoking | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/970000/969900/969839/c5b64e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Hearth Inn & Suites Union City [](https://www.expedia.com/Union-City-Hotels-Country-Hearth-Inn-Suites-Union-City.h969839.Hotel-Information) Union City 8.6/10 Excellent (552 reviews) "Very clean nice staff and well run " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) zach $72 nightly $85 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Country-Hearth-Inn-Suites-Union-City.h969839.Hotel-Information) ![Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/a77daa89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premier Room, 1 Bedroom, Non Smoking | Bathroom | Combined shower/tub, free toiletries, towels, soap](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/5fa7b845.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/91bb8871.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New Orleans Inn Portageville [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) Portageville 8.0/10 Very Good (742 reviews) "Parking was good, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Corey $60 nightly $65 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/47690ac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/bf40a512.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/d5d0cfa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) [](https://www.expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) Sikeston 8.4/10 Very Good (739 reviews) "Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky $60 nightly $69 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/1fd79e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/65f9cbe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down comforters, desk, iron/ironing board](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/4b95ba78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8150000/8144200/8144106/58cb82c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sikeston Southwest by IHG [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) Sikeston 8.6/10 Excellent (447 reviews) "Stay was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kourtney $87 nightly $99 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Holiday-Inn-Express-Suites-Sikeston-Southwest.h8144106.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f7d6d20c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Accessible (Hearing) | Iron/ironing board, bed sheets](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f54017fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/2c1de1a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/4fbaaf96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Union City [](https://www.expedia.com/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information) Union City 9.6/10 Exceptional (172 reviews) "Spotless , friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gail $120 nightly $143 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/fa4ef12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/980dd49e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/3798eaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/91000000/90830000/90821500/90821467/b7350700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Yard Inn and Suite [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) Sikeston 6.8/10 (123 reviews) "Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew $48 nightly $54 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Country-Yard-Inn-And-Suite.h90821467.Hotel-Information) ![Free daily full breakfast](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/13d95c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/42667f54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Laptop workspace, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/b775798e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Sikeston I-55 [](https://www.expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) Sikeston 8.4/10 Very Good (1,005 reviews) "Great stay, everything was clean and comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles $82 nightly $94 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/c1609da5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/643f6c59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking | Iron/ironing board, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/ba65d6e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14600/14571/bfe56101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Union City US 51 [](https://www.expedia.com/Union-City-Hotels-Quality-Inn-Union-City-US-51.h14571.Hotel-Information) Union City 8.4/10 Very Good (494 reviews) "Nice room" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) José Ricardo $67 nightly $80 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Quality-Inn-Union-City-US-51.h14571.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/e1e1641a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Non Smoking, Microwave | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/c064d51d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/w1290h938x0y0-9734f59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, 1 King Bed, Non Smoking, Microwave | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/22000000/21830000/21826900/21826840/73298be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hospitality House Union City I 69 / US 51 [](https://www.expedia.com/Union-City-Hotels-Hospitality-House.h21826840.Hotel-Information) Union City 6.8/10 (380 reviews) "Easy to check in.. Clean Room..Lots of food options near by.. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pooran $58 nightly $69 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Hospitality-House.h21826840.Hotel-Information) ![Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/679acee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/55ffcc39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/1ca277a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/988800/988758/a5038447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Charleston/Sikeston East MO [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) Charleston 6.8/10 (623 reviews) "Affordable for a quick one night stay. Restaurant and gas station next to hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Annette $62 nightly $69 total Mar 3 - Mar 4 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Super-8-By-Wyndham-Charleston-MO.h988758.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-6f8601de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/de7767c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 1 King Bed with Sofa bed | Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w3995h2667x0y0-c8905780.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111247500/111247452/w4000h2662x0y0-82d0e62d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Sikeston [](https://www.expedia.com/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) Sikeston 9.2/10 Wonderful (12 reviews) "This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason $134 nightly $152 total Feb 22 - Feb 23 Total with taxes and fees [](https://www.expedia.com/Towneplace-Suites-By-Marriott-Sikeston.h111247452.Hotel-Information) ![Suite, 2 Queen Beds, Non Smoking | Individually furnished, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/a2256dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/07a7ee12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking | Individually furnished, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/bb2e8b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/40000000/39520000/39519200/39519116/8feb1e66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Union City, TN [](https://www.expedia.com/Union-City-Hotels-MainStay-Suites.h39519116.Hotel-Information) Union City 8.6/10 Excellent (44 reviews) "Very clean room, friendly staff! I would highly recommend this place! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lydia $95 nightly $113 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-MainStay-Suites.h39519116.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/c970f53d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/832ea567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/2feca880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/40000000/39580000/39579100/39579081/6140f4df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Union City by IHG [](https://www.expedia.com/Union-City-Hotels-Holiday-Inn-Express-Suites-Union-City.h39579081.Hotel-Information) Union City 9.4/10 Exceptional (313 reviews) "The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela $103 nightly $123 total Mar 1 - Mar 2 Total with taxes and fees [](https://www.expedia.com/Union-City-Hotels-Holiday-Inn-Express-Suites-Union-City.h39579081.Hotel-Information) ![1 bedroom, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/be0d2e33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/3d86dbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/7335ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/22100/22041/717baff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn and Suites by Wyndham Sikeston [](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Sikeston 7.2/10 Good (1,001 reviews) "Everything was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James $68 nightly $78 total Feb 24 - Feb 25 Total with taxes and fees [](https://www.expedia.com/Sikeston-Hotels-Days-Inn-And-Suites-By-Wyndham-Sikeston.h22041.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-07&endDate=2026-03-08®ionId=3000349349&adults=2&lodging=LODGE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=AA_SPRING_PROMO_3000349349) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEast-Prairie-Lodges.d3000349349-aaLodges.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEast-Prairie-Lodges.d3000349349-aaLodges.Travel-Guide-Accommodation) ## Top East Prairie Hotel Reviews ![Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)](https://images.trvl-media.com/lodging/1000000/40000/34800/34745/f91b29ea_y.jpg) ### Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 10/10 Excellent "Very friendly and had an amazing stay so peaceful " [](https://expedia.com/Sikeston-Hotels-Travel-Inn-Suites.h34745.Hotel-Information) ![Hampton Inn Sikeston](https://images.trvl-media.com/lodging/26000000/25180000/25178200/25178175/d0739759_y.jpg) ### Hampton Inn Sikeston 10/10 Excellent "Very clean room and pleasant staff " [](https://expedia.com/Sikeston-Hotels-Hampton-Inn-Sikeston.h25178175.Hotel-Information) ![Drury Inn & Suites Sikeston, MO](https://images.trvl-media.com/lodging/1000000/30000/24300/24210/8e55cf67_y.jpg) ### Drury Inn & Suites Sikeston, MO 10/10 Excellent "upgrade to a suite" [](https://expedia.com/Sikeston-Hotels-Drury-Inn-Suites-Sikeston.h24210.Hotel-Information) ![ For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.](https://images.trvl-media.com/lodging/35000000/34330000/34322400/34322352/537131b5_y.jpg) ### For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier. 10/10 Excellent "Clean and convenient! Great stay, we will be back!" [](https://expedia.com/Hornbeak-Hotels-For-Larger-Groups-Right-On-Reelfoot-Lake-Private-Dock-And-Pier.h34322352.Hotel-Information) ![Reelfoot Lake Inn](https://images.trvl-media.com/lodging/17000000/16770000/16770000/16769945/755237c5_y.jpg) ### Reelfoot Lake Inn 10/10 Excellent "Room was spotless, and the staff was great. " [](https://expedia.com/Union-City-Hotels-Reelfoot-Lake-Inn.h16769945.Hotel-Information) ![Hampton Inn Union City](https://images.trvl-media.com/lodging/71000000/70820000/70814800/70814746/f7d6d20c_y.jpg) ### Hampton Inn Union City 10/10 Excellent "The staff was very friendly and courteous. The hotel was spotless. Very clean inside and out." [](https://expedia.com/Union-City-Hotels-Hampton-Inn-Union-City.h70814746.Hotel-Information) ![Best Western Plus Sikeston](https://images.trvl-media.com/lodging/9000000/8430000/8420600/8420572/29a4ab37_y.jpg) ### Best Western Plus Sikeston 10/10 Excellent "Thestaff at the front counter was awesome." [](https://expedia.com/Sikeston-Hotels-Best-Western-Plus-Sikeston.h8420572.Hotel-Information) ![Sleep Inn at Discovery Park of America](https://images.trvl-media.com/lodging/39000000/38310000/38309600/38309567/2a51d3d0_y.jpg) ### Sleep Inn at Discovery Park of America 10/10 Excellent "Great place ! Breakfast was amazing " [](https://expedia.com/Union-City-Hotels-Sleep-Inn.h38309567.Hotel-Information) ![New Orleans Inn Portageville ](https://images.trvl-media.com/lodging/39000000/38980000/38979800/38979739/2d9e6936_y.jpg) ### New Orleans Inn Portageville 10/10 Excellent "Clean room, Comfy bed and quiet surroundings made my quick stay comfortable. Reasonable price, close to restaurants, head shop, gas station and grocery. " [](https://expedia.com/Hayti-Hotels-New-Orleans-Inn.h38979739.Hotel-Information) ## Find out more about East Prairie ## East Prairie Lodges information | Number of reviews | 7,877 | | ----------------- | --------- | | Accommodation | 11 Lodges | | Lowest Price | $54 | | Highest Price | $152 | ## Frequently asked questions ### Why book your lodge in East Prairie with Expedia? ### How can I find cheap lodges in East Prairie? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Motels in Bertrand ](https://www.expedia.com/Bertrand-Motels.d3000349285-aaMotels.Travel-Guide-Accommodation) - [Motels in Charleston ](https://www.expedia.com/Charleston-Motels.d7182-aaMotels.Travel-Guide-Accommodation) - [Palaces in Charleston ](https://www.expedia.com/Charleston-Palaces.d7182-aaPalaces.Travel-Guide-Accommodation) - [Cabin Rentals in Charleston ](https://www.expedia.com/Charleston-Cabins.d7182-aaCabins.Travel-Guide-Accommodation) - [Bertrand Hotels ](https://www.expedia.com/Bertrand-Hotels.d3000349285.Travel-Guide-Hotels) - 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