
Effingham Vacations from $377
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Your Effingham Vacation
When a city break is calling, answer it with a vacation package to Effingham. With all your travel arrangements in place before you leave, all you need to do here is focus on making unforgettable memories. Your trip to Effingham wouldn't be complete without visiting its popular attractions, like Lynches River State Park. No matter your travel plans or budget, organizing a tailored Effingham vacation is a walk in the park with Expedia.
The Latest Effingham vacation packages
Price found within the past 48 hours. Click for updated prices.


Residence Inn Marriott Florence
Price was $765, price is now $644 per person
$644
per person
Dec 3 - Dec 7
found 1 day ago
Roundtrip non-stop flight included
Manchester (MHT) to Florence (FLO)
8.8/10 Excellent! (423 reviews)
We had a wonderful stay here. The room was very nice, with a kitchen, sitting area and king bed. Nice vanity in bath. But the mattress was soft, sinking in the middle. The staff here Charon and Cynthia serving breakfast were some of the nicest people we've met while eating breakfast. They displayed and kept the food items well stocked. The breakfast was great, we had sausage, both turkey and pork, eggs, toast, waffles, pastries, cereals, with a nut and topping station, juice, coffee, milk, yogurt, fresh pineapple, bananas, apples just to name a few. It was awesome!! Will be back here. I will have to say at check out the staff person was away with a note at the front desk, "I've walked away, will return later". This was the busiest time of day check out time and they weren't there to man the station. Only negative thing to say here.
Reviewed on Aug 23, 2025

Hotel Florence, Tapestry Collection by Hilton
Price was $820, price is now $713 per person
$713
per person
Dec 3 - Dec 7
found 12 hours ago
Roundtrip non-stop flight included
Manchester (MHT) to Florence (FLO)
8.8/10 Excellent! (580 reviews)
Very unique property. Great room and bath. No closet but didn’t miss it. It had a hanging trolley. Vicytors restaurant is superb. Staff is more than gracious.
Reviewed on Sep 18, 2025


Hilton Garden Inn Florence
Price was $775, price is now $681 per person
$681
per person
Dec 3 - Dec 7
found 12 hours ago
Roundtrip non-stop flight included
Manchester (MHT) to Florence (FLO)
8.4/10 Very Good! (229 reviews)
Everything was alright except the bathroom door which has a habit to close from outside and to open it you have to have a nickel or a dime to unscrew the lock as was suggested by the front desk clerk. :))
Reviewed on Sep 18, 2025
Effingham Hotel Deals

Park Inn by Radisson Florence, SC
1729 Mandeville Road, Florence, SC
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $100 total per night from Sep 28 to Sep 29
$100 total
Sep 28 - Sep 29
Total with taxes and fees
9/10 Wonderful! (2,151 reviews)
"Conveniently located for stopover on a long journey. Giod parking soace and a friendly front desk staff."
Reviewed on Sep 25, 2025

Howard Johnson by Wyndham Florence
2038 W Lucas Street, I-95 Exit 164, Florence, SC
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $73 total per night from Sep 28 to Sep 29
$73 total
Sep 28 - Sep 29
Total with taxes and fees
8.6/10 Excellent! (2,371 reviews)
"This is a really nice hotel. Thought the room was like perfect quite honestly and I would definitely stay here again"
Reviewed on Sep 19, 2025

Comfort Inn & Suites
527 Woody Jones Blvd, Florence, SC
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $117 total per night from Sep 30 to Oct 1
$117 total
Sep 30 - Oct 1
Total with taxes and fees
9/10 Wonderful! (1,089 reviews)
"The staff at check in was very friendly and cheerful. Property is convenient to restaurants and is clean and quiet. Love the gnome decorations!"
Reviewed on Sep 24, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.