As of Jul 2, 2022, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Tuscumbia - Muscle Shoals on Jul 17, 2022 start from $86.45, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.