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Featured Florence Luxury Hotels

See all 98 Properties in Florence

Estimated price for 1 night/2 adults

The ColdWater Inn
The ColdWater Inn
3.5 out of 5.0 712 Hwy 72 W, Tuscumbia, AL
4.4/5 (150 reviews)
$109/ night for 2 guests

Clean, ornately furnished in old southern charm style. Breakfast had good variety, fresh food & coffee. The lady in charge of the breakfast area kept it stocked, clean & she was very pleasant!

Reviewed on Jun 5, 2019
Clarion Inn
Clarion Inn
3.0 out of 5.0 4900 Hatch Blvd, Sheffield, AL
Free Cancellation
3.6/5 (402 reviews)
$59/ night for 2 guests

The service was great. Some things need to be refurbished but a great value.

Reviewed on May 21, 2019
Baymont by Wyndham Florence/Muscle Shoals
Baymont by Wyndham Florence/Muscle Shoals
2.5 out of 5.0 115 Ana Drive, Florence, AL
Free Cancellation
3.8/5 (375 reviews)
$67/ night for 2 guests

Wondetful everything clean room and friendly staff

Reviewed on May 12, 2019
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Recently booked Luxury Hotels in Florence

Baymont by Wyndham Florence/Muscle Shoals
2.5 out of 5.0
Last booking: 10 hours ago

A few days away keeps your stress at bay, so book your trip to Florence and prepare to unwind. Tremendous experiences, scrumptious eats, and the most stunning photo opportunities: these are just some of the reasons to take a vacation to Florence. You'll snag seats to the most sought-after shows, treat yourself to decadent dishes, and eye-guzzle the top monuments and landmarks in the region. Where else would you stay but a luxury hotel? Extravagant experiences are right up your alley, so get your elegant hotel in Florence on Expedia.com today, and your relaxing getaway is off to a good start.

5-Star Vacations in Florence

It turns out plenty of folks have decided to call it home -- how is that for proof that Florence is full of an incredible array of activities? Whether you’re looking to spend your vacation dining on fine seasonal food or exploring museums in Florence, you'll never be disappointed. Florence is full of outstanding hotels as well as fantastic food, so you can count on a spectacular stay. Book early to ensure you snag a room!

Your luxury vacation is your chance to live your best life, including dining at 5-star restaurants and getting VIP seats. When you're smart enough to book travel on Expedia.com, you never have to limit yourself. Thanks to our impressive room rates, you can always afford to check out the area's most intriguing activities. After many hours of adventure, your luxury accommodation awaits. Don't fall asleep before making use of your room's luxury bath products or asking the concierge for advice on tomorrow's plans. The luxury hotels in Florence will have you feeling the serenity in the blink of an eye.

Find Luxury Florence Hotels Now

When you’ve got your heart set on an upscale getaway in Florence, Expedia.com is here to save the day. Browse the abundance of reviews on fabulous hotels and find the perfect vacation rental. Luxury accommodations offer amenities like spacious suites and concierge services. Many deluxe accommodations in Florence even feature impeccable suites, and it's likely you'll discover pampering spa treatments in your hotel. Book your luxury experience in Florence now, and soon you'll be soaking up luxury in style!