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Featured Florida Keys Boutique Hotels

See all 511 Hotels in Florida Keys
Azul del Mar

Azul del Mar

104300 Overseas Highway, Key Largo
3.5 out of 5.0
4.5 out of 5 (182 reviews)
Relaxing RetreatMy husband and I stayed 2 nights after driving the Keys and spending 3 nights in Key West. We were greeted warmly, our room was perfect. Loved the adult only atmosphere. The only disappointment was no swimming pool. I didn't notice it when I booked . We enjoyed the small private beach area. Would ...
  Aug 23, 2017

$159

$159
Artist House Key West

Artist House Key West

534 Eaton Street, Key West
3.5 out of 5.0
4.6 out of 5 (103 reviews)
Awesome staff, great locationWe chose the Artist House for the location, close to dining and entertainment. The Anne Suite was beautiful and so large. At breakfast they offered a wide variety of baked goods plus fruit, yogurt, and other choices. We missed Happy Hour most days but were always made to feel welcome. Overall, I ...
  Nov 19, 2017

$179

$179
Artist House on Fleming

Artist House on Fleming

1016 Fleming St., Key West
3.5 out of 5.0
4.6 out of 5 (129 reviews)
Quiet place. Great Location. Friendly Staff.Very welcoming check in. They make it very easy to come and go as you please. Bikes are available for rent but it’s not a long walk to Duval St, Mallory Square, or North Harbor. Comfortable rooms, would definitely stay again. The peaceful pool and fountain were great to chill at after a long fun ...
  Nov 11, 2017

$169

$169
Weatherstation Inn

Weatherstation Inn

57 Front St, Key West
2.5 out of 5.0
4.7 out of 5 (387 reviews)
Excellent place to stay in awesome location!We absolutely loved everything about Weatherstation Inn! Check in was smooth and easy. Rooms were very clean and large. Bottled water was very nice since it was so hot outside. Location was fantastic. Definitely will return for another stay in the future!
  Aug 17, 2017

$279

$279
The Saint Hotel Key West, Autograph Collection

The Saint Hotel Key West, Autograph Collection

417 Eaton Street, Key West
3.5 out of 5.0
4.5 out of 5 (231 reviews)
Great Location to Duval and all the activitiesWe really enjoyed The Saint and the fact we could walk about everywhere we wanted. The people were super nice and the hotel had a fun new vibe about it. Beautiful pool. And somehow tucked right in the middle of everything. Our room was super small but that was all that was available. Was prices but ...
  May 11, 2017

$219

$219
Albury Court Hotel - Key West

Albury Court Hotel - Key West

1030 Eaton St, Key West
3.0 out of 5.0
4.0 out of 5 (1,528 reviews)
The lady at the front desk was very nice and friendly and did all above and beyond the expectations
  Nov 22, 2017

$159

$159
Almond Tree Inn

Almond Tree Inn

512 Truman Ave, Key West
3.5 out of 5.0
4.8 out of 5 (765 reviews)
Great lodging and amenities near Duval Street,Great pool, nice landscaping, comfortable room, wonderful breakfast. Short walk to Duval Street.
  Nov 23, 2017

$305

$305
Silver Palms Inn

Silver Palms Inn

830 Truman Ave, Key West
3.5 out of 5.0
4.4 out of 5 (2,454 reviews)
Nice and clean hotelThe Hotel is in a good location and room was very clean and comfortable.
  Nov 21, 2017

$179

$179
The Cabana Inn Key West-Adults Only

The Cabana Inn Key West-Adults Only

413 Applerouth Lane, Key West
3.0 out of 5.0
4.5 out of 5 (806 reviews)
Centrally located near all attractions. Had a great experience. This is our 2nd stay here. My only gripes are that the coffee in the morning runs out quickly and you are left waiting for it and that it can be noisey. Noise is mainly from the street and from neighbors upstairs. Room was great. Hot tub and pool was nice. Staff is ...
  Nov 23, 2017

$164

$164
The Marker Waterfront Resort Key West

The Marker Waterfront Resort Key West

200 William Street, Key West
4.0 out of 5.0
4.6 out of 5 (831 reviews)
nice hotel close to Mallory SquateBeautiful hotel close to Duval and Mallory Square. Beautiful pool and clean rooms and bathrooms. We'll be back.
  Nov 21, 2017

$259

$259
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
4.0 out of 5.0
4.3 out of 5 (1,063 reviews)
great experience...loved the complimentary rum punch 😁
  Nov 21, 2017

$164

$164
Amara Cay Resort

Amara Cay Resort

80001 Overseas Hwy, Islamorada
3.5 out of 5.0
4.3 out of 5 (1,197 reviews)
awesome placeeverything looks new condition, very clean, ac very cold.
  Sep 5, 2017

$219

$219
Lighthouse Court Hotel - Key West

Lighthouse Court Hotel - Key West

902 Whitehead St, Key West
3.5 out of 5.0
4.1 out of 5 (898 reviews)
We were able to check in early, staff was very professional, had great ideas and suggestions for tours, dinner reservations and gave us maps all marked up to give the exact locations of activities. Rooms as recently updated, close to the pool and the hotel is great location for Key West.
  Nov 21, 2017

$179

$179
The Gardens Hotel

The Gardens Hotel

526 Angela Street, Key West
4.0 out of 5.0
4.8 out of 5 (417 reviews)
Wonderful find!The hotel was centrally located to the fun, bustling activities on Duval Street, yet was quiet and intimate. We enjoyed our stay and hope to return next time we visit Key West.
  Nov 13, 2017

$194

$194
Orchid Key Inn

Orchid Key Inn

1004 Duval St, Key West
3.5 out of 5.0
4.8 out of 5 (660 reviews)
Pampered, relaxing, retreat The hotel was the perfect oasis after exploring Key West each day of our vacation.
  Nov 14, 2017

$283

$283
La Concha Hotel & Spa

La Concha Hotel & Spa

430 Duval St, Key West
4.0 out of 5.0
4.1 out of 5 (1,865 reviews)
Right in the heart of Old Town. You can walk to everything.
  Nov 24, 2017

$195

$195
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key
3.5 out of 5.0
4.1 out of 5 (507 reviews)
Party weekend Nice views and quiet Bay side staff was wonderful and very accommodating!
  Nov 21, 2017

$116

$116
The Marquesa Hotel

The Marquesa Hotel

600 Fleming Street, Key West
3.5 out of 5.0
4.9 out of 5 (186 reviews)
Unique HotelWe loved everything about the hotel-from the initial greeting to the checkout. It is not your standard hotel where everything is alike. Since it is a converted conch house, every room is different. The staff was/is excellent with special kudos going to Bruce. The landscaping in the pool area and ...
  Sep 1, 2017

$300

$300
NYAH Key West-Adults Only

NYAH Key West-Adults Only

420 Margaret Street, Key West
2.5 out of 5.0
4.4 out of 5 (818 reviews)
Great location and very friendly and caring servicBig rooms with a big locker, own bathroom with is really nice and cleans every day! Great service and really nice location, great outdoor facilities with 3 pools 1 spar and a lot of possibilitys to sit or lay down. Breakfast was a good selection of different things, where everyone finds something. ...
  Nov 19, 2017

$116

$116
Paradise Inn Key West-Adults Only

Paradise Inn Key West-Adults Only

819 Simonton Street, Key West
3.5 out of 5.0
4.6 out of 5 (841 reviews)
Perfect locationWe really enjoyed Key West. We drove from Naples. We expected Key West to be recovering from Hurricaine Irma but Key West seemed to have been spared. Some of the other islands were not so lucky. It’s a great place to stay. Colourful and laid back.
  Nov 22, 2017

$249

$249
Map

Recently booked Boutique Hotels in Florida Keys

Holiday Inn Key Largo
3.0 out of 5.0
Last booking: 3 hours ago
Southernmost Beach Resort
4.0 out of 5.0
Last booking: 5 hours ago
Banana Bay Resort and Marina
2.5 out of 5.0
Last booking: 6 hours ago
Hyatt Place Marathon Florida Keys
3.0 out of 5.0
Last booking: 6 hours ago
The Gates Hotel Key West
4.0 out of 5.0
Last booking: 6 hours ago
Sheraton Suites Key West
3.5 out of 5.0
Last booking: 7 hours ago
Hyatt Centric Key West Resort and Spa
4.0 out of 5.0
Last booking: 7 hours ago
Heron House - Adult Only
3.5 out of 5.0
Last booking: 7 hours ago
Key Largo Bay Marriott Beach Resort
3.5 out of 5.0
Last booking: 7 hours ago

Reserve a Florida Keys Boutique Room that is Uniquely You

After you land in Florida Keys, you'll realize that all your concerns are left behind and you can relax for the next several days. You'll uncover that a numerous people had the same escape plan as you. Florida Keys has seen an 86% increase over last year. Wherever you may holiday, you still bring your exceptional self on your trip, and Expedia offers bookings at the most avant-garde and authentic boutique properties in Florida Keys.

Small Lodging with Plenty of Personality

With your cutting-edge fashion and a need to dance to your own beat, part of the perfect vacation is discovering an abode in Florida Keys that echoes you. Unlike their more straight-laced, big-chain brothers that aspire to please everybody, these small hotels love displaying their offbeat charisma. Most boutique hotels have traits like:

  • An idiosyncratic style you will not be able to get in bigger hotels, from individually fashioned rooms to cozy meeting areas, and thoughtful touches that make it seem homey.
  • A more exclusive stay, since boutique hotels typically have less than 100 rooms.
  • A highly personalized type of service, where they add thoughtful touches like fresh-cut flowers.
  • A desirable address in the center of Florida Keys. You'll be just steps from the town's coolest attractions.

Indulge in Everything Florida Keys Offers!

Florida Keys has rooms to satisfy all types of budgets and preferences that create a visit memorable.

Book a Room with Views Inside and Out in Florida Keys

If you absolutely must have a stay in a Florida Keys boutique hotel that will make you feel like a guest in a stylish home, book quickly, since everybody is as well. Thankfully, Expedia has all the top rates on the most exceptional boutique accommodations. A one-of-a-kind stay is just a few taps away!