Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Florida Keys Hyatt Hotels Hotels

See all 357 Hotels in Florida Keys
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

601 Front St, Key West
4.0 out of 5.0
4.5 out of 5 (683 reviews)
Great location near Duval Street. The hotel has beautiful rooms with great views. The staff could n … - 

$229

$229
Hyatt Residence Club Key West, Beach House

Hyatt Residence Club Key West, Beach House

5051 Overseas Highway, Key West
3.5 out of 5.0
4.5 out of 5 (228 reviews)
Perfect hotel on Key West It is away from the busy part of the Island, yet is close enough to everything. Rooms are very comf … - 

$319

$319
Hyatt Residence Club Key West, Windward Pointe

Hyatt Residence Club Key West, Windward Pointe

3675 South Roosevelt Boulevard, Key West
3.5 out of 5.0
4.6 out of 5 (164 reviews)
Nice hotel, clean. Wish our room had a better view of the water. Cool pool and outdoor games - 

$309

$309
Map

Recently booked Florida Keys hotels

Marina Del Mar Resort and Marina
2.5 out of 5.0
Last booking: 24 minutes ago
Coconut Cay Resort & Marina
2.0 out of 5.0
Last booking: 1 hour ago
The Grand Guesthouse
2.5 out of 5.0
Last booking: 1 hour ago
Parrot Key Hotel & Resort
4.0 out of 5.0
Last booking: 2 hours ago
Paradise Inn Key West - Adult Exclusive
3.5 out of 5.0
Last booking: 3 hours ago
Best Western Hibiscus Motel
2.5 out of 5.0
Last booking: 3 hours ago
NYAH Key West - Adult Exclusive
2.5 out of 5.0
Last booking: 3 hours ago
The Pelican Key Largo Cottages
2.0 out of 5.0
Last booking: 3 hours ago
Pier House Resort & Spa
4.0 out of 5.0
Last booking: 3 hours ago

Hyatt Hotels Florida Keys Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Hyatt Hotels hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Hyatt Hotels Florida Keys hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Hyatt Hotels locations may even offer extra little benefits and discounts for frequent travelers.