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Featured Florida Keys Independent Hotels

See all 496 Hotels in Florida Keys
24 North Hotel Key West

24 North Hotel Key West

3820 North Roosevelt Boulevard, Key West
4.5 out of 5.0
4.1 out of 5 (1,066 reviews)
very nice hotel close enough to downtown key west lost my key card a couple times eh sh** happens right? they had no problem in replacing it cleaning … - 

$139

$139
Ibis Bay Beach Resort

Ibis Bay Beach Resort

3101 N. Roosevelt Blvd, Key West
3.0 out of 5.0
3.7 out of 5 (1,614 reviews)
On the water Clean, comfortable room with a peaceful water view. Prompt shuttle to town was a big plus. Friendly … - 

$143

$143
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
4.5 out of 5.0
4.5 out of 5 (3,111 reviews)
Checked in late, no problem they are open 24 hours! When I told them it was my moms birthday, the c … - 

$194

$194
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
4.5 out of 5.0
4.5 out of 5 (310 reviews)
Incredible stay at Ocean Edge BEAUTIFUL HOTEL Right from the start the "experience at Ocean Edge was incredible". We pulled up to a beautiful hot … - 

$166

$166
Sheraton Suites Key West

Sheraton Suites Key West

2001 S Roosevelt Blvd, Key West
4.0 out of 5.0
4.3 out of 5 (2,096 reviews)
Nice hotel This hotel is nice. The shuttle is very useful to go to downtown. - 

$151

$151
Hilton Garden Inn Key West,The Keys Collection

Hilton Garden Inn Key West,The Keys Collection

3850 N Roosevelt Blvd, Key West
4.0 out of 5.0
4.1 out of 5 (342 reviews)
This is a very nice hotel, very clean, staff super friendly. I definitely recommend it - 

$146

$146
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
4.5 out of 5.0
4.3 out of 5 (1,076 reviews)
Nice Hotel -- Beautiful Poor and Bar Area The Gates is a nice hotel at the very north end of Key West. The have a shuttle that runs every hou … - 

$169

$169
Silver Palms Inn

Silver Palms Inn

830 Truman Ave, Key West
4.0 out of 5.0
4.4 out of 5 (2,468 reviews)
Great hotel Friendly, professional staff. Clean comfortable and well appointed rooms and a good location just a … - 

$179

$179
The Marker Waterfront Resort Key West

The Marker Waterfront Resort Key West

200 William Street, Key West
4.5 out of 5.0
4.5 out of 5 (853 reviews)
Great Resort Valet parking is sweet, however know that there is a $30/day parking fee on top of the $35/day reso … - 

$175

$175
The Southernmost Inn-Adults Only

The Southernmost Inn-Adults Only

525 United Street, Key West
3.0 out of 5.0
4.1 out of 5 (849 reviews)
Nice hotel, friendly staff, good breakfast. We had a great time. The staff was very friendly. The folks at the front desk were very accommodati … - 

$169

$169
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key
4.0 out of 5.0
4.1 out of 5 (524 reviews)
Clean Hotel at reasonable price Two couples stayed in this town house but it would hold 3 couples. Great access to a canal with ful … - 

$116

$116
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

527 Caribbean Drive, Key Largo
3.0 out of 5.0
3.6 out of 5 (1,858 reviews)
Pluses and minuses This is an older property in a beautiful setting next to a marina. Our room was somewhat small, but … - 

$119

$119
Hyatt Place Marathon Florida Keys

Hyatt Place Marathon Florida Keys

1996 Overseas Highway, Marathon
3.5 out of 5.0
4.5 out of 5 (1,345 reviews)
Nice hotel in Marathon Nice hotel,free breakfast and free parking. Good shower and fridge in room Nice pool. - 

$180

$180
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West
3.5 out of 5.0
4.4 out of 5 (1,344 reviews)
Convient location The hotel staff were personable and helpful. The staff made our stay enjoyable. Expect a lot of int … - 

$149

$149
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St, Key West
4.0 out of 5.0
4.3 out of 5 (1,506 reviews)
Very nice place to stay, close to everything in Key West. Rooms were very nice & clean. Staff very … - 

$149

$149
La Concha Hotel & Spa

La Concha Hotel & Spa

430 Duval St, Key West
4.5 out of 5.0
4.1 out of 5 (1,778 reviews)
Enjoyed my stay, however, the bathroom is very tight. - 

$195

$195
Drift Hotel

Drift Hotel

95320 Overseas Hwy, Key Largo
3.0 out of 5.0
3.9 out of 5 (15 reviews)
Clean, quiet Hotel with room for some improvements Check in was not the standard expected businesslike event I am used to. Pleasant greeting by the la … - 

$129

$129
Fairfield Inn & Suites by Marriott Key West, Keys Collection

Fairfield Inn & Suites by Marriott Key West, Keys Collection

3852 North Roosevelt Boulevard, Key West
3.5 out of 5.0
4.0 out of 5 (883 reviews)
Nice hotel, good location. Hits all the marks, great breakfast. Roosters from 3 AM to 6 AM, we're not fun. - 

$149

$149
NYAH Key West-Adults Only

NYAH Key West-Adults Only

420 Margaret Street, Key West
3.0 out of 5.0
4.4 out of 5 (822 reviews)
Little KW Gem This place is incredible. Super clean. Awesome, helpful staff. - 

$149

$149
Skipjack Resort & Marina

Skipjack Resort & Marina

19 Sombrero Blvd, Marathon
3.5 out of 5.0
4.2 out of 5 (151 reviews)
Convenient and Close to Everything on Marathon With the very real and impending threat of Hurricane Irma looming, I was in need of a room for the … - 

$169

$169
Map

Recently booked Florida Keys hotels

La Concha Hotel & Spa
4.5 out of 5.0
Last booking: 1 minute ago
Marina Del Mar Resort and Marina
3.0 out of 5.0
Last booking: 10 minutes ago
Holiday Inn Key Largo
3.5 out of 5.0
Last booking: 24 minutes ago
The Reach, A Waldorf Astoria Resort
4.5 out of 5.0
Last booking: 39 minutes ago
Southernmost Beach Resort
4.5 out of 5.0
Last booking: 43 minutes ago
Chelsea House Hotel - Key West
3.0 out of 5.0
Last booking: 45 minutes ago
The Pelican Key Largo Cottages
2.5 out of 5.0
Last booking: 50 minutes ago
Holiday Inn Express Hotel & Suites Marathon
3.0 out of 5.0
Last booking: 1 hour ago
Courtyard by Marriott Key Largo
3.5 out of 5.0
Last booking: 1 hour ago

Independent Florida Keys Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.