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Featured Florida Keys Independent Hotels

See all 699 Hotels in Florida Keys
Ibis Bay Beach Resort

Ibis Bay Beach Resort

3101 N. Roosevelt Blvd, Key West
3.0 out of 5.0
3.7 out of 5 (1,611 reviews)
On the water Clean, comfortable room with a peaceful water view. Prompt shuttle to town was a big plus. Friendly … - 

$143

$143
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
4.5 out of 5.0
4.5 out of 5 (312 reviews)
This is the place to relax..!! From your check in to check out you are going to feel very comfortable and everyone is very nice, s … - 

$166

$166
Silver Palms Inn

Silver Palms Inn

830 Truman Ave, Key West
4.0 out of 5.0
4.4 out of 5 (1,818 reviews)
Great location! Perfect location to be able to get to Duval St. You are a bit away from the action but it is very a … - 

$179

$179
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
4.5 out of 5.0
4.3 out of 5 (170 reviews)
Beautiful hotel and experience We were given an upgrade for no apparent reason except good customer service and kindness. It was a … - 

$231

$231
The Southernmost Inn-Adults Only

The Southernmost Inn-Adults Only

525 United Street, Key West
3.0 out of 5.0
4.1 out of 5 (851 reviews)
Nice hotel, friendly staff, good breakfast. We had a great time. The staff was very friendly. The folks at the front desk were very accommodati … - 

$179

$179
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key
4.0 out of 5.0
4.1 out of 5 (527 reviews)
Super nice staff Super nice people very helpful . !!!!!!!!!!!!!!!! ........................... - 

$116

$116
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

527 Caribbean Drive, Key Largo
2.5 out of 5.0
3.6 out of 5 (1,858 reviews)
nice hotel close to Sharky's and Ocean Divers Nice place great staff. One of the cleaning staff was talking Very loud early in the morning. That … - 

$119

$119
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West
3.5 out of 5.0
4.4 out of 5 (1,344 reviews)
Convient location The hotel staff were personable and helpful. The staff made our stay enjoyable. Expect a lot of int … - 

$149

$149
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St, Key West
4.0 out of 5.0
4.3 out of 5 (1,507 reviews)
Very nice place to stay, close to everything in Key West. Rooms were very nice & clean. Staff very … - 

$149

$149
Drift Hotel

Drift Hotel

95320 Overseas Hwy, Key Largo
3.0 out of 5.0
3.9 out of 5 (15 reviews)
Clean, quiet Hotel with room for some improvements Check in was not the standard expected businesslike event I am used to. Pleasant greeting by the la … - 

$129

$129
NYAH Key West-Adults Only

NYAH Key West-Adults Only

420 Margaret Street, Key West
3.0 out of 5.0
4.4 out of 5 (822 reviews)
Little KW Gem This place is incredible. Super clean. Awesome, helpful staff. - 

$159

$159
Skipjack Resort & Marina

Skipjack Resort & Marina

19 Sombrero Blvd, Marathon
3.5 out of 5.0
4.2 out of 5 (151 reviews)
Convenient and Close to Everything on Marathon With the very real and impending threat of Hurricane Irma looming, I was in need of a room for the … - 

$169

$169
Creekside Inn Islamorada

Creekside Inn Islamorada

90611 Old Highway, Islamorada
2.5 out of 5.0
3.5 out of 5 (650 reviews)
Great hotel and location Was a great experience. They have done a great job in renovating the rooms. Everything was clean an … - 

$125

$125
Amy Slate's Amoray Dive Resort

Amy Slate's Amoray Dive Resort

104250 Overseas Hwy, Key Largo
2.0 out of 5.0
3.9 out of 5 (896 reviews)
Affordable Stay We stayed at this hotel for one night and the experience was fine. The rooms are dated but ours was … - 

$89

$89
Blackfin Resort and Marina

Blackfin Resort and Marina

4650 Overseas Hwy., Marathon
2.5 out of 5.0
3.7 out of 5 (541 reviews)
Bike ride overnight stop. we stayed two different nights. Very friendly staff, and nicely decorated rooms. - 

$124

$124
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

99340 Overseas Highway, Key Largo
2.5 out of 5.0
3.7 out of 5 (764 reviews)
Ok, wouldn't rule it out for a return visit Everything was ok but the mattress was so bad that if you tried to sit up in bed you could feel the … - 

$87

$87
Southwinds Motel

Southwinds Motel

1321 Simonton Street, Key West
2.5 out of 5.0
3.9 out of 5 (770 reviews)
Pleasantly surprised that the hotel doesn't have a better rating online. We would stay again i f we … - 

$129

$129
Seashell Motel & Key West Hostel

Seashell Motel & Key West Hostel

718 South Street, Key West
2.0 out of 5.0
2.7 out of 5 (648 reviews)
Old location but clean and comfortable could use some upkeep but would stay again - 

$70

$70
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
4.5 out of 5.0
4.5 out of 5 (1,042 reviews)
Tranquil More then expected , Ottis a staff member went above and beyond! Very clean and wonderful. - 

$179

$179
Amara Cay Resort

Amara Cay Resort

80001 Overseas Hwy, Islamorada
4.0 out of 5.0
4.3 out of 5 (1,201 reviews)
awesome place everything looks new condition, very clean, ac very cold. - 

$219

$219
Map

Recently booked Florida Keys hotels

The Gates Hotel Key West
4.5 out of 5.0
Last booking: 9 minutes ago
Silver Palms Inn
4.0 out of 5.0
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Artist House Key West
4.0 out of 5.0
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Southernmost Beach Resort
4.5 out of 5.0
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Alexander Palms Court
3.0 out of 5.0
Last booking: 1 hour ago
Ibis Bay Beach Resort
3.0 out of 5.0
Last booking: 1 hour ago
Heron House Court - Adult Only
3.5 out of 5.0
Last booking: 2 hours ago
Pier House Resort & Spa
4.5 out of 5.0
Last booking: 2 hours ago
The Marker Waterfront Resort Key West
4.5 out of 5.0
Last booking: 2 hours ago

Independent Florida Keys Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.