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Featured Florida Keys Independent Hotels

See all 511 Hotels in Florida Keys
Ibis Bay Beach Resort

Ibis Bay Beach Resort

3101 N. Roosevelt Blvd, Key West
2.5 out of 5.0
3.7 out of 5 (1,686 reviews)
Very comfortable environment, clean rooms Great onsite restaurant, had a surf & turf that was awesome! Easy access to everywhere in Key West. … - 

$143

$143
Hilton Garden Inn Key West,The Keys Collection

Hilton Garden Inn Key West,The Keys Collection

3850 N Roosevelt Blvd, Key West
3.5 out of 5.0
4.1 out of 5 (327 reviews)
Good Key West Lodging My wife and I were in Key West for the boat races and stayed at the Garden Inn. We used the shuttle … - 

$125

$125
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key
3.5 out of 5.0
4.1 out of 5 (507 reviews)
Party weekend Nice views and quiet Bay side staff was wonderful and very accommodating! - 

$116

$116
The Southernmost Inn-Adults Only

The Southernmost Inn-Adults Only

525 United Street, Key West
2.5 out of 5.0
4.1 out of 5 (837 reviews)
Great location. Lovely hotel in the middle of the Old Town. I had a great stay in this hotel. It is also a short wa … - 

$179

$179
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

99340 Overseas Highway, Key Largo
2.0 out of 5.0
3.7 out of 5 (751 reviews)
Friendly staff It was a real pleasure staying there with very friendly staff. - 

$94

$94
Fairfield Inn & Suites by Marriott Key West, Keys Collection

Fairfield Inn & Suites by Marriott Key West, Keys Collection

3852 North Roosevelt Boulevard, Key West
3.0 out of 5.0
4.0 out of 5 (877 reviews)
Away from traffic and quiet breakfast was the best we have ever had stayed in a lot of high rated h … - 

$149

$149
24 North Hotel Key West

24 North Hotel Key West

3820 North Roosevelt Boulevard, Key West
4.0 out of 5.0
4.1 out of 5 (1,041 reviews)
Hotel has a great shuttle to Mallory Square! The hotel was nice. The shuttle was fantastic because we did not have to use our rental car the who … - 

$137

$137
La Concha Hotel & Spa

La Concha Hotel & Spa

430 Duval St, Key West
4.0 out of 5.0
4.1 out of 5 (1,864 reviews)
Amazing Location Our stay was very pleasant. We got there super early around 12:00 pm and they were able to provide … - 

$195

$195
Hyatt Place Marathon Florida Keys

Hyatt Place Marathon Florida Keys

1996 Overseas Highway, Marathon
3.0 out of 5.0
4.5 out of 5 (1,329 reviews)
Lovely hotel with excellent staff The foyer and desk staff provide a very good first impression that is reflected in the rest of the … - 

$161

$161
Silver Palms Inn

Silver Palms Inn

830 Truman Ave, Key West
3.5 out of 5.0
4.4 out of 5 (2,454 reviews)
Nice and clean hotel The Hotel is in a good location and room was very clean and comfortable. - 

$179

$179
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
4.0 out of 5.0
4.3 out of 5 (1,063 reviews)
great experience...loved the complimentary rum punch 😁 - 

$164

$164
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
4.0 out of 5.0
4.3 out of 5 (153 reviews)
Perfect location. Walking distance to everything. Great views to watch sunset. Good food at Bistro. - 

$161

$161
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

601 Front St, Key West
4.0 out of 5.0
4.5 out of 5 (1,288 reviews)
Overall, great property. Treated ourselves to a nice hotel for a last minute trip to Key West. The property was beautiful, r … - 

$239

$239
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
4.0 out of 5.0
4.4 out of 5 (1,422 reviews)
Nice Key West spot This was a very nice hotel and friendly hotel staff. The ‘beach’ is very small, but nice, and excel … - 

$279

$279
Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

97450 Overseas Highway, Key Largo
3.5 out of 5.0
4.7 out of 5 (96 reviews)
Short stay for our anniversary, but had a great time. Beautiful property and staff was very friendl … - 

$212

$212
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

527 Caribbean Drive, Key Largo
2.5 out of 5.0
3.6 out of 5 (2,046 reviews)
Great location with friendly staff and nice pool area. The rooms are clean and the rate was excelle … - 

$119

$119
Captain Pip's at Knight's Key Inn

Captain Pip's at Knight's Key Inn

40 Kyle Way W, Marathon
3.0 out of 5.0
4.5 out of 5 (40 reviews)
Good for a night or two Nice clean efficiency unit. Newly renovated. A nice place to take a break half way through the Keys … - 

$109

$109
Amy Slate's Amoray Dive Resort

Amy Slate's Amoray Dive Resort

104250 Overseas Hwy, Key Largo
2.0 out of 5.0
3.9 out of 5 (890 reviews)
We enjoyed the premises. Very nice location with dive boat on the property. Did not dive with them … - 

$86

$86
Southwinds Motel

Southwinds Motel

1321 Simonton Street, Key West
2.0 out of 5.0
3.9 out of 5 (756 reviews)
very nice stay - 200 yards away from ocean - 50 feet away from ana's cuban cafe --- get the cubano sandwhich - 1 s … - 

$169

$169
Duval House

Duval House

815 Duval St, Key West
3.0 out of 5.0
4.2 out of 5 (673 reviews)
Rooms were old but in very good condition. Hotel staff very pleasant. Loved the veranda room. Break … - 

$189

$189
Map

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Independent Florida Keys Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.