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Featured Florida Keys Independent Hotels

See all 1,047 Hotels in Florida Keys
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
4.0 out of 5.0
4.5 out of 5 (340 reviews)
Nice hotel by the marina Great stay. Friendly staff. Quiet and relaxing stay. Rooms were very comfortable. Great place to un … - 

$179

$179
Ibis Bay Beach Resort

Ibis Bay Beach Resort

3101 N. Roosevelt Blvd, Key West
3.0 out of 5.0
3.7 out of 5 (1,610 reviews)
great spot loved it, super clean, super comfortable, that was perfect. - 

$239

$239
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
4.5 out of 5.0
4.2 out of 5 (191 reviews)
Great location The hotel staff was very professional in all aspects.The location was great,close to everything.The … - 

$254

$254
Silver Palms Inn

Silver Palms Inn

830 Truman Ave, Key West
3.5 out of 5.0
4.4 out of 5 (1,816 reviews)
Weekend in Key west Everything was great except the free drink tickets... the only alcohol they were good for was sangr … - 

$153

$153
The Southernmost Inn-Adults Only

The Southernmost Inn-Adults Only

525 United Street, Key West
3.0 out of 5.0
4.1 out of 5 (868 reviews)
Cozy inn We stayed at the Inn in mid October. Our 1st hotel had issues post hurricane so we found this place … - 

$229

$229
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key
4.0 out of 5.0
4.1 out of 5 (550 reviews)
Walls very thin. Noisy on the road. Large balcony with a good view overlooking water. - 

$165

$165
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West
3.5 out of 5.0
4.4 out of 5 (1,368 reviews)
Quaint, homey and welcoming lodging We spent four days at the Heron House Court. The accommodations were clean and comfortable and the … - 

$189

$189
NYAH Key West-Adults Only

NYAH Key West-Adults Only

420 Margaret Street, Key West
3.0 out of 5.0
4.4 out of 5 (831 reviews)
3 days 2 nights of an awesome experience. Will aga Excellent price and staff where excellent. Will stay over and over again. - 

$199

$199
Southwinds Motel

Southwinds Motel

1321 Simonton Street, Key West
2.0 out of 5.0
3.9 out of 5 (784 reviews)
Great location with friendly staff Lovely room close to the southern most point. Front desk staff were exceptionally helpful and alway … - 

$208

$208
Seashell Motel & Key West Hostel

Seashell Motel & Key West Hostel

718 South Street, Key West
2.0 out of 5.0
2.7 out of 5 (658 reviews)
Best deal in key west Great staff great facilities close to everything it is the best deal financially in key west. I wou … - 

$118

$118
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

527 Caribbean Drive, Key Largo
3.0 out of 5.0
3.6 out of 5 (1,852 reviews)
nice and clean. great restuarant next door. canal view. - 

$169

$169
Skipjack Resort & Marina

Skipjack Resort & Marina

19 Sombrero Blvd, Marathon
3.5 out of 5.0
4.2 out of 5 (157 reviews)
nice place to stay Great place to stay - we went snorkeling in Marathon and we stayed here and it was very nice. Every … - 

$159

$159
Heron House - Adult Only

Heron House - Adult Only

512 Simonton St, Key West
3.5 out of 5.0
4.3 out of 5 (1,520 reviews)
Close to Duval! This was a small but very cozy place to stay! It was clean. The free breakfast was good and plentif … - 

$159

$159
Creekside Inn Islamorada

Creekside Inn Islamorada

90611 Old Highway, Islamorada
3.0 out of 5.0
3.5 out of 5 (657 reviews)
the Hotel was very close to the highway so the noise was very loud from it - 

$125

$125
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
4.5 out of 5.0
4.5 out of 5 (1,051 reviews)
Pleasant Very nice place to stay with private beach , definitely recommend and wish i could stay more then o … - 

$349

$349
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

99340 Overseas Highway, Key Largo
2.0 out of 5.0
3.7 out of 5 (785 reviews)
The place is rustic, and older but very nice cozy and clean. Recommend. - 

$120

$120
Drift Hotel

Drift Hotel

95320 Overseas Hwy, Key Largo
3.0 out of 5.0
4.1 out of 5 (21 reviews)
Cozy, quaint little gem with direct access to the we just stayed here for two days and absolutely loved it! Quaint little place with direct access to … - 

$139

$139
Bayside Inn Key Largo

Bayside Inn Key Largo

99490 Overseas Hwy, Key Largo
3.0 out of 5.0
3.0 out of 5 (1,758 reviews)
Older facility needs updating. WiFi doesn’t work. No beach to speak of. You get what you pay for. N … - 

$159

$159
Chelsea House Hotel - Key West

Chelsea House Hotel - Key West

709 Truman Ave, Key West
3.0 out of 5.0
4.2 out of 5 (602 reviews)
Great location The hotel was conveniently located, within a 5-minute walk to Duval Street. The hotel was very quai … - 

$224

$224
Amara Cay Resort

Amara Cay Resort

80001 Overseas Hwy, Islamorada
4.0 out of 5.0
4.3 out of 5 (1,209 reviews)
only one night but great experience We decided to extend a business trip a few days from Orlando and picked the Keys ( warmer). At rand … - 

$233

$233
Map

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Independent Florida Keys Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.