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Featured Florida Keys Independent Hotels

See all 848 Properties in Florida Keys
Havana Cabana at Key West

Havana Cabana at Key West

3420 N. Roosevelt Blvd, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 
4.0 out of 5 (63 reviews)
Great location My husband and I stayed at this hotel for 2 nights, and it was the beat time ever. We celebrated ou … - 

Havana Cabana at Key West$127

Havana Cabana at Key West$127
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (569 reviews)
Beautiful Hotel The hotel facade and hampton's style decorating is perfection, the grounds and facilities excellent … - 

Oceans Edge Key West Resort, Hotel & Marina$134

Oceans Edge Key West Resort, Hotel & Marina$134
Bayside Inn Key Largo

Bayside Inn Key Largo

99490 Overseas Hwy, Key Largo
    2.5 out of 5.0
     
     
    3.0 out of 5 (1,836 reviews)
    Beautiful sunset Affordable area and close walking distance to any necessities. Best sunset view in the keys. - 

    Bayside Inn Key Largo$79

    Bayside Inn Key Largo$79
    Ibis Bay Beach Resort

    Ibis Bay Beach Resort

    3101 N. Roosevelt Blvd, Key West
      2.5 out of 5.0
       
       
      3.8 out of 5 (1,701 reviews)
      Everything You Need! Ibis Bay Beach Resort has everything you need for a perfect Key West getaway- onsite restaurant wit … - 

      Ibis Bay Beach Resort$121

      Ibis Bay Beach Resort$121
      Margaritaville Key West Resort & Marina

      Margaritaville Key West Resort & Marina

      245 Front Street, Key West
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      4.3 out of 5 (311 reviews)
      Highly recommend We only stayed for a short time. Hotel was nice and clean. Staff was great, lots of amenities and r … - 

      Margaritaville Key West Resort & Marina$250

      Margaritaville Key West Resort & Marina$250
      The Perry Hotel Key West

      The Perry Hotel Key West

      7001 Shrimp Road, Key West
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      4.6 out of 5 (218 reviews)
      Better than expected Off the beaten path but a welcome change of pace with a great atmosphere. Industrial modern feel wi … - 

      The Perry Hotel Key West$161

      The Perry Hotel Key West$161
      Marina Del Mar Resort and Marina

      Marina Del Mar Resort and Marina

      527 Caribbean Drive, Key Largo
      • Free Cancellation
      • Reserve now, pay when you stay
      2.5 out of 5.0
       
       
      3.6 out of 5 (1,897 reviews)
      Nice hotel with Pool. Hotel located along a harbour with fishing boats and diving support. „diver down“. It is apleasure … - 
      Albury Court Hotel - Key West

      Albury Court Hotel - Key West

      1030 Eaton St, Key West
        3.0 out of 5.0
         
         
        4.0 out of 5 (1,484 reviews)
        Nice hotel within walking distance to everything. Excellent and friendly staff. Property very well kept. Rooms clean and amenities in room were nice … - 

        Albury Court Hotel - Key West$169

        Albury Court Hotel - Key West$169
        Heron House - Adult Only

        Heron House - Adult Only

        512 Simonton St, Key West
          3.5 out of 5.0
           
           
          4.3 out of 5 (1,641 reviews)
          Close to Duval, very adult friendly and calm Beautiful relaxed hotel with beautiful courtyard. Will def stay again next Key West trip! About 2 b … - 

          Heron House - Adult Only$119

          Heron House - Adult Only$119
          Skipjack Resort & Marina

          Skipjack Resort & Marina

          19 Sombrero Blvd, Marathon
            3.0 out of 5.0
             
             
            4.1 out of 5 (241 reviews)
            Great hotel if you want to get away and relax Hotel is perfect for a getaway. It’s off the main road and is very quiet. Check in was super fast a … - 

            Skipjack Resort & Marina$159

            Skipjack Resort & Marina$159
            Amara Cay Resort

            Amara Cay Resort

            80001 Overseas Hwy, Islamorada
            • Free Cancellation
            • Reserve now, pay when you stay
            3.5 out of 5.0
             
             
            4.3 out of 5 (1,329 reviews)
            As much fishing in 5 days as possible Definitely give this place 5 stars! Great location, the cleanest rooms. Great drinks at bar . Great … - 

            Amara Cay Resort$199

            Amara Cay Resort$199
            Creekside Inn Islamorada

            Creekside Inn Islamorada

            90611 Old Highway, Islamorada
              2.5 out of 5.0
               
               
              3.6 out of 5 (768 reviews)
              close to local amenities, including beach. Good location. best to get a room on the waterfront side of the building as you will be facing the … - 

              Creekside Inn Islamorada$133

              Creekside Inn Islamorada$133
              Silver Palms Inn

              Silver Palms Inn

              830 Truman Ave, Key West
              • Free Cancellation
              • Reserve now, pay when you stay
              3.5 out of 5.0
               
               
              4.5 out of 5 (1,866 reviews)
              Lovely renovated hotel with great proximity We loved this hotel. It is newly renovated with spacious, spotless rooms. It is a bit off Duval Str … - 

              Silver Palms Inn$159

              Silver Palms Inn$159
              Chesapeake Beach Resort

              Chesapeake Beach Resort

              83409 Overseas Hwy, Islamorada
                2.5 out of 5.0
                 
                 
                3.7 out of 5 (608 reviews)
                Islamorada motel This really nice motel on Islamorada is still on the mend from Irma, but is priced accordingly. Gre … - 

                Chesapeake Beach Resort$142

                Chesapeake Beach Resort$142
                Heron House Court - Adult Only

                Heron House Court - Adult Only

                412 Frances St, Key West
                  3.0 out of 5.0
                   
                   
                  4.4 out of 5 (1,482 reviews)
                  Great location Such a lovely place to ‘come home to’ after your day enjoying the city. - 

                  Heron House Court - Adult Only$129

                  Heron House Court - Adult Only$129
                  Seashell Motel & Key West Hostel

                  Seashell Motel & Key West Hostel

                  718 South Street, Key West
                  • Free Cancellation
                  • Reserve now, pay when you stay
                  1.5 out of 5.0
                   
                   
                  2.8 out of 5 (723 reviews)
                  Affordable stay Very close to the beach and within walking distance to Duval St. where there are plenty of places t … - 

                  Seashell Motel & Key West Hostel$90

                  Seashell Motel & Key West Hostel$90
                  La Siesta Resort & Marina

                  La Siesta Resort & Marina

                  80241 Overseas Highway, Islamorada
                  • Free Cancellation
                  • Reserve now, pay when you stay
                  3.0 out of 5.0
                   
                   
                  3.8 out of 5 (664 reviews)
                  Nice hotel close to beach Nice hotel on beach, with free rentals , staff was friendly - 
                  Tranquility Bay Beachfront Hotel and Resort

                  Tranquility Bay Beachfront Hotel and Resort

                  2600 Overseas Hwy, Marathon
                  • Free Cancellation
                  • Reserve now, pay when you stay
                  4.0 out of 5.0
                   
                   
                  4.5 out of 5 (1,131 reviews)
                  Beautiful view from any angle Spacious and very clean No contact at all from management staff which was disappointing after 8 day … - 

                  Tranquility Bay Beachfront Hotel and Resort$224

                  Tranquility Bay Beachfront Hotel and Resort$224
                  Drop Anchor Resort and Marina

                  Drop Anchor Resort and Marina

                  84959 Overseas Highway, 222, Islamorada
                    3.0 out of 5.0
                     
                     
                    4.3 out of 5 (903 reviews)
                    Hotel had beautiful white sand and view First time ever going to the Keys. We stayed in Key Largo, Islamorada and Key West.Drop Anchor Reso … - 
                    Lime Tree Bay Resort

                    Lime Tree Bay Resort

                    68500 Overseas Hwy, Long Key
                      3.5 out of 5.0
                       
                       
                      4.1 out of 5 (697 reviews)
                      Beautiful views with a great amenities The bed was uncomfortable but aside from that this was the perfect place to stay. Close to so many … - 

                      Lime Tree Bay Resort$119

                      Lime Tree Bay Resort$119
                      Map

                      Recently booked Florida Keys hotels

                      Skipjack Resort & Marina
                      3.0 out of 5.0
                      Last booking: 3 hours ago
                      Casa Marina, A Waldorf Astoria Resort
                      4.0 out of 5.0
                      Last booking: 4 hours ago
                      Fairfield Inn and Suites by Marriott Key West
                      3.5 out of 5.0
                      Last booking: 4 hours ago
                      Tranquility Bay Beachfront Hotel and Resort
                      4.0 out of 5.0
                      Last booking: 4 hours ago
                      Amara Cay Resort
                      3.5 out of 5.0
                      Last booking: 4 hours ago
                      Looe Key Reef Resort
                      2.5 out of 5.0
                      Last booking: 4 hours ago
                      Santa Maria Suites
                      4.0 out of 5.0
                      Last booking: 4 hours ago
                      Pelican Cove Resort & Marina
                      3.0 out of 5.0
                      Last booking: 4 hours ago
                      Chesapeake Beach Resort
                      2.5 out of 5.0
                      Last booking: 4 hours ago

                      Independent Florida Keys Hotel Guide

                      Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

                      You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.