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Florida Keys Hotel Rooms at the Independent

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Florida Keys Hotels

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Featured Florida Keys Independent Hotels

See all 330 Hotels in Florida Keys
Key West Escapes - Luxury Yoga Vacations

Key West Escapes - Luxury Yoga Vacations

Tropical Street, Key West
4.0 out of 5.0
Santa Maria Suites

Santa Maria Suites

1401 Simonton St, Key West
4.0 out of 5.0
4.8 out of 5 (359 reviews)
In a crowded Key West, best accommodations When we arrived, we were a bit disappointed, looking at the hotel from the street...it doesn't look … - 

$419

$419
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82, Islamorada
4.0 out of 5.0
4.4 out of 5 (640 reviews)
Nice hotel with lots to do. Very good experience. Good food at all the places on site where we ate. Convenient to lots of other … - 

$229

$229
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
4.0 out of 5.0
4.5 out of 5 (458 reviews)
Great place to stay We loved everything about this place! Beautiful grounds, great pools, nice little beach area for ki … - 

$299

$299
Key West Yacht Life

Key West Yacht Life

Key West Harbour Yacht Club Stock Island, Key West
4.0 out of 5.0
Oceans Edge Key West Hotel & Marina

Oceans Edge Key West Hotel & Marina

5950 Peninsular Avenue, Key West
3.5 out of 5.0
4.3 out of 5 (75 reviews)
Excellente ,good, super!!!!!!!!!!!!!!!!!!!! !!!!! - 

$169

$169
The Gardens Hotel

The Gardens Hotel

526 Angela Street, Key West
4.0 out of 5.0
4.8 out of 5 (114 reviews)
Amazing hotel. Slice of heaven. Hotel that looks like plantation homes set in a secret garden. I really enjoyed al … - 

$249

$249
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Recently booked Florida Keys hotels

DoubleTree Resort by Hilton Grand Key - Key West
3.5 out of 5.0
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Duval House
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Sunset Cove Beach Resort
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Hilton Key Largo Resort
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24 North Hotel Key West
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Heron House - Adult Only
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Independent Florida Keys Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.