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Featured Florida Keys Independent Hotels

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Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
4.5 out of 5.0
4.5 out of 5 (375 reviews)
Beautiful Facilities Rooms and pools were very nice. Hotel bar, restaurant and Starbucks add 18% gratuity to anything yo … - 

$305

$305
Amara Cay Resort

Amara Cay Resort

80001 Overseas Hwy, Islamorada
4.0 out of 5.0
4.3 out of 5 (1,220 reviews)
Responsive hotel management and the property wasn’t affected by Irma. - 

$321

$321
Ibis Bay Beach Resort

Ibis Bay Beach Resort

3101 N. Roosevelt Blvd, Key West
3.0 out of 5.0
3.7 out of 5 (1,621 reviews)
Nice room and staff. All was good except breakfast was disappointing compared to other places we stayed that were 1/4 th … - 

$279

$279
Banana Bay Resort & Marina

Banana Bay Resort & Marina

4590 Overseas Highway, Marathon
3.5 out of 5.0
3.5 out of 5 (1,392 reviews)
Very nice, updated hotel with a good vibe Very nice, updated hotel with a good vibe and beautiful sunsets. Haley at the front desk was great, … - 

$234

$234
Creekside Inn Islamorada

Creekside Inn Islamorada

90611 Old Highway, Islamorada
3.0 out of 5.0
3.5 out of 5 (673 reviews)
Great experience and the staff was very freinly and helpful - 

$170

$170
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key
4.0 out of 5.0
4.1 out of 5 (577 reviews)
The hotel is nice, I just didn't like that it did not have a beach where you could swim. The sheets … - 

$253

$253
Heron House Court - Adult Only

Heron House Court - Adult Only

412 Frances St, Key West
3.0 out of 5.0
4.4 out of 5 (1,387 reviews)
Will stay there again Excellent staff - Roland, Michael, and Deanna are top shelf people. Very helpful and friendly answe … - 

$219

$219
Amy Slate's Amoray Dive Resort

Amy Slate's Amoray Dive Resort

104250 Overseas Hwy, Key Largo
2.5 out of 5.0
3.9 out of 5 (924 reviews)
Great for those using Amoray Scuba/Snorkeling Serv This is a great hotel for those using Amoray Services. The location is good and it is right on the … - 

$152

$152
The Southernmost Inn-Adults Only

The Southernmost Inn-Adults Only

525 United Street, Key West
2.5 out of 5.0
4.1 out of 5 (886 reviews)
Quiet and comfortable The Southernmost Inn is clean and the staff is nice, and breakfast is available daily - 

$299

$299
Silver Palms Inn

Silver Palms Inn

830 Truman Ave, Key West
4.0 out of 5.0
4.4 out of 5 (1,812 reviews)
Exceeded our expectations!! We come to Key West for an semi annual anniversary trip. Our usual hotel, the Casa Marina, had exce … - 

$299

$299
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
4.5 out of 5.0
4.3 out of 5 (210 reviews)
Nice hotel, central, amenities good. We arrived early so we left our luggage and wandered around. They texted when our room was ready, l … - 

$399

$399
The Perry Hotel Key West

The Perry Hotel Key West

7001 Shrimp Road, Key West
4.5 out of 5.0
4.6 out of 5 (108 reviews)
Very good value close to downtown Key West The decor and marina views are excellent. The hotel is about a 15 minute drive via car or shuttle t … - 

$304

$304
Skipjack Resort & Marina

Skipjack Resort & Marina

19 Sombrero Blvd, Marathon
3.0 out of 5.0
4.2 out of 5 (166 reviews)
We booked The Skipjack at the last minute for a brief one night stay. close to a beach and good res … - 

$239

$239
Southwinds Motel

Southwinds Motel

1321 Simonton Street, Key West
2.5 out of 5.0
3.9 out of 5 (801 reviews)
Key West Anniversary Vacation We enjoyed their friendly and helpful staff, great location just a block off Duvall Street and a co … - 

$258

$258
Chelsea House Hotel - Key West

Chelsea House Hotel - Key West

709 Truman Ave, Key West
3.0 out of 5.0
4.2 out of 5 (620 reviews)
Great service and clean rooms. The staff was amazing. The environmental was friendly and I will def … - 

$314

$314
Chesapeake Beach Resort

Chesapeake Beach Resort

83409 Overseas Hwy, Islamorada
2.5 out of 5.0
3.8 out of 5 (540 reviews)
Good value hotel The hotel had considerable damage from the hurricane so no beach access at this time and a lot of u … - 

$249

$249
Marina Del Mar Resort and Marina

Marina Del Mar Resort and Marina

527 Caribbean Drive, Key Largo
2.5 out of 5.0
3.6 out of 5 (1,848 reviews)
Perfect Location Marina Del Mar was right across the marina from the dive company I was diving with. It was a 5 minu … - 

$179

$179
Bayside Inn Key Largo

Bayside Inn Key Largo

99490 Overseas Hwy, Key Largo
3.0 out of 5.0
3.0 out of 5 (1,766 reviews)
Nice hotel close to beach We enjoyed the pool and beach area. It had comfy beach chairs and lounge chairs to enjoy the view o … - 

$169

$169
Duval House

Duval House

815 Duval St, Key West
3.5 out of 5.0
4.2 out of 5 (701 reviews)
Mile 0 Fest lodging was perfect We stayed for 2 nights. We had a one day pass for Mile 0 Fest. It is pretty much right in the middl … - 

$299

$299
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
4.5 out of 5.0
4.5 out of 5 (1,064 reviews)
Best resort on Marathon Great resort with well maintained facilities and property. Pools, beach and grounds are beautiful. … - 

$499

$499

Recently booked Florida Keys hotels

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Skipjack Resort & Marina
3.0 out of 5.0
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Creekside Inn Islamorada
3.0 out of 5.0
Last booking: 41 minutes ago
Bayview Inn & Marina
2.5 out of 5.0
Last booking: 44 minutes ago
Southernmost Beach Resort
4.5 out of 5.0
Last booking: 46 minutes ago
Fairfield Inn and Suites by Marriott Key West
3.0 out of 5.0
Last booking: 49 minutes ago
Bay Harbor Lodge
3.5 out of 5.0
Last booking: 55 minutes ago

Independent Florida Keys Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.