Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Check prices on hotels in Florida Keys

Best deal Best deal Aug 17 - Aug 19
Tonight Tonight Jun 20 - Jun 21
This weekend This weekend Jun 22 - Jun 24
Next weekend Next weekend Jun 29 - Jul 1

Featured Florida Keys Independent Hotels

See all 848 Properties in Florida Keys
Havana Cabana at Key West

Havana Cabana at Key West

3420 N. Roosevelt Blvd, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
3.5 out of 5.0
 
 
3.9 out of 5 (59 reviews)
Nicely renovated Hotel was nice, the pool was great, however, there were 30 something filler of “resort usage fee” p … - 
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
  • Free Cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (567 reviews)
Beautiful Hotel The hotel facade and hampton's style decorating is perfection, the grounds and facilities excellent … - 

Oceans Edge Key West Resort, Hotel & Marina$134

Oceans Edge Key West Resort, Hotel & Marina$134
Bayside Inn Key Largo

Bayside Inn Key Largo

99490 Overseas Hwy, Key Largo
    2.5 out of 5.0
     
     
    3.0 out of 5 (1,835 reviews)
    Beautiful sunset Affordable area and close walking distance to any necessities. Best sunset view in the keys. - 

    Bayside Inn Key Largo$79

    Bayside Inn Key Largo$79
    Ibis Bay Beach Resort

    Ibis Bay Beach Resort

    3101 N. Roosevelt Blvd, Key West
      2.5 out of 5.0
       
       
      3.8 out of 5 (1,701 reviews)
      Everything You Need! Ibis Bay Beach Resort has everything you need for a perfect Key West getaway- onsite restaurant wit … - 

      Ibis Bay Beach Resort$121

      Ibis Bay Beach Resort$121
      Margaritaville Key West Resort & Marina

      Margaritaville Key West Resort & Marina

      245 Front Street, Key West
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      4.3 out of 5 (307 reviews)
      Highly recommend We only stayed for a short time. Hotel was nice and clean. Staff was great, lots of amenities and r … - 

      Margaritaville Key West Resort & Marina$250

      Margaritaville Key West Resort & Marina$250
      The Perry Hotel Key West

      The Perry Hotel Key West

      7001 Shrimp Road, Key West
      • Free Cancellation
      • Reserve now, pay when you stay
      4.0 out of 5.0
       
       
      4.6 out of 5 (217 reviews)
      Better than expected Off the beaten path but a welcome change of pace with a great atmosphere. Industrial modern feel wi … - 

      The Perry Hotel Key West$153

      The Perry Hotel Key West$153
      Marina Del Mar Resort and Marina

      Marina Del Mar Resort and Marina

      527 Caribbean Drive, Key Largo
        2.5 out of 5.0
         
         
        3.6 out of 5 (1,897 reviews)
        Nice hotel with Pool. Hotel located along a harbour with fishing boats and diving support. „diver down“. It is apleasure … - 

        Marina Del Mar Resort and Marina$109

        Marina Del Mar Resort and Marina$109
        Albury Court Hotel - Key West

        Albury Court Hotel - Key West

        1030 Eaton St, Key West
          3.0 out of 5.0
           
           
          4.0 out of 5 (1,485 reviews)
          Nice hotel within walking distance to everything. Excellent and friendly staff. Property very well kept. Rooms clean and amenities in room were nice … - 

          Albury Court Hotel - Key West$169

          Albury Court Hotel - Key West$169
          Heron House - Adult Only

          Heron House - Adult Only

          512 Simonton St, Key West
            3.5 out of 5.0
             
             
            4.3 out of 5 (1,639 reviews)
            Close to Duval, very adult friendly and calm Beautiful relaxed hotel with beautiful courtyard. Will def stay again next Key West trip! About 2 b … - 

            Heron House - Adult Only$129

            Heron House - Adult Only$129
            Skipjack Resort & Marina

            Skipjack Resort & Marina

            19 Sombrero Blvd, Marathon
              3.0 out of 5.0
               
               
              4.1 out of 5 (238 reviews)
              Great hotel if you want to get away and relax Hotel is perfect for a getaway. It’s off the main road and is very quiet. Check in was super fast a … - 

              Skipjack Resort & Marina$149

              Skipjack Resort & Marina$149
              Amara Cay Resort

              Amara Cay Resort

              80001 Overseas Hwy, Islamorada
                3.5 out of 5.0
                 
                 
                4.3 out of 5 (1,327 reviews)
                Awesome keys property Well appointed boutique resort in keys. Great resort will return. - 

                Amara Cay Resort$199

                Amara Cay Resort$199
                Creekside Inn Islamorada

                Creekside Inn Islamorada

                90611 Old Highway, Islamorada
                  2.5 out of 5.0
                   
                   
                  3.6 out of 5 (766 reviews)
                  Stay at Creekside Inn Nice stop on our way to Key West. Clean and comfortable for a reasonable price. - 

                  Creekside Inn Islamorada$125

                  Creekside Inn Islamorada$125
                  Silver Palms Inn

                  Silver Palms Inn

                  830 Truman Ave, Key West
                    3.5 out of 5.0
                     
                     
                    4.5 out of 5 (1,866 reviews)
                    Lovely renovated hotel with great proximity We loved this hotel. It is newly renovated with spacious, spotless rooms. It is a bit off Duval Str … - 

                    Silver Palms Inn$159

                    Silver Palms Inn$159
                    Chesapeake Beach Resort

                    Chesapeake Beach Resort

                    83409 Overseas Hwy, Islamorada
                      2.5 out of 5.0
                       
                       
                      3.7 out of 5 (606 reviews)
                      Islamorada motel This really nice motel on Islamorada is still on the mend from Irma, but is priced accordingly. Gre … - 

                      Chesapeake Beach Resort$122

                      Chesapeake Beach Resort$122
                      Heron House Court - Adult Only

                      Heron House Court - Adult Only

                      412 Frances St, Key West
                        3.0 out of 5.0
                         
                         
                        4.4 out of 5 (1,481 reviews)
                        Great location Such a lovely place to ‘come home to’ after your day enjoying the city. - 

                        Heron House Court - Adult Only$119

                        Heron House Court - Adult Only$119
                        Seashell Motel & Key West Hostel

                        Seashell Motel & Key West Hostel

                        718 South Street, Key West
                        • Free Cancellation
                        • Reserve now, pay when you stay
                        1.5 out of 5.0
                         
                         
                        2.8 out of 5 (723 reviews)
                        Affordable stay Very close to the beach and within walking distance to Duval St. where there are plenty of places t … - 

                        Seashell Motel & Key West Hostel$39

                        Seashell Motel & Key West Hostel$39
                        La Siesta Resort & Marina

                        La Siesta Resort & Marina

                        80241 Overseas Highway, Islamorada
                          3.0 out of 5.0
                           
                           
                          3.8 out of 5 (662 reviews)
                          Quiet, Relaxing Resort on the water. Very pleased with the cleanliness and well-kept grounds of this resort. The staff was accommodating … - 
                          Tranquility Bay Beachfront Hotel and Resort

                          Tranquility Bay Beachfront Hotel and Resort

                          2600 Overseas Hwy, Marathon
                          • Free Cancellation
                          • Reserve now, pay when you stay
                          4.0 out of 5.0
                           
                           
                          4.5 out of 5 (1,130 reviews)
                          Beautiful view from any angle Spacious and very clean No contact at all from management staff which was disappointing after 8 day … - 

                          Tranquility Bay Beachfront Hotel and Resort$149

                          Tranquility Bay Beachfront Hotel and Resort$149
                          Drop Anchor Resort and Marina

                          Drop Anchor Resort and Marina

                          84959 Overseas Highway, 222, Islamorada
                            3.0 out of 5.0
                             
                             
                            4.3 out of 5 (903 reviews)
                            Hotel had beautiful white sand and view First time ever going to the Keys. We stayed in Key Largo, Islamorada and Key West.Drop Anchor Reso … - 

                            Drop Anchor Resort and Marina$161

                            Drop Anchor Resort and Marina$161
                            Lime Tree Bay Resort

                            Lime Tree Bay Resort

                            68500 Overseas Hwy, Long Key
                              3.5 out of 5.0
                               
                               
                              4.1 out of 5 (696 reviews)
                              Beautiful views with a great amenities The bed was uncomfortable but aside from that this was the perfect place to stay. Close to so many … - 

                              Lime Tree Bay Resort$119

                              Lime Tree Bay Resort$119
                              Map

                              Recently booked Florida Keys hotels

                              Lime Tree Bay Resort
                              3.5 out of 5.0
                              Last booking: 7 minutes ago
                              Courtyard by Marriott Marathon Florida Keys
                              3.0 out of 5.0
                              Last booking: 13 minutes ago
                              Courtyard by Marriott Key West Waterfront
                              3.0 out of 5.0
                              Last booking: 21 minutes ago
                              Drop Anchor Resort and Marina
                              3.0 out of 5.0
                              Last booking: 55 minutes ago
                              Ocean Key Resort - A Noble House Resort
                              4.0 out of 5.0
                              Last booking: 1 hour ago
                              24 North Hotel Key West
                              4.0 out of 5.0
                              Last booking: 1 hour ago
                              Best Western Key Ambassador Resort Inn
                              2.5 out of 5.0
                              Last booking: 3 hours ago
                              Holiday Inn Express Hotel & Suites Marathon
                              2.5 out of 5.0
                              Last booking: 4 hours ago
                              The Gates Hotel Key West
                              4.0 out of 5.0
                              Last booking: 5 hours ago

                              Independent Florida Keys Hotel Guide

                              Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Florida Keys, Florida. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Florida Keys hotels guarantees an unparalleled level of comfort and quality.

                              You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Florida Keys Independent locations may even offer extra little benefits and discounts for frequent travelers.