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Top 10 Hotels in Florida Keys

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Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon 33050

4.0 out of 5.0
4.5 out of 5 (980 reviews)

Located on a private beach in Marathon, Tranquility Bay Beachfront Hotel and Resort is a 5-minute walk from the turtle …

$169
Captain Pips Marina & Hideaway

Captain Pips Marina & Hideaway

1410 Overseas Hwy, Marathon 33050-2117

3.0 out of 5.0
4.2 out of 5 (420 reviews)

Situated on the waterfront, this hotel is 0.6 mi (0.9 km) from The Turtle Hospital and 2.3 mi (3.6 km) from Sombrero Beach. …

$84
Captain Pip's at Knight's Key Inn

Captain Pip's at Knight's Key Inn

40 Kyle Way W, Marathon 33050

3.0 out of 5.0
4.4 out of 5 (7 reviews)

Situated in Marathon, this aparthotel is within 1 mi (2 km) of Pigeon Key Foundation and Seven Mile Bridge. The Turtle …

$129
Glunz Ocean Beach Hotel & Resort

Glunz Ocean Beach Hotel & Resort

351 East Ocean Drive, Key Colony Beach 33051

3.0 out of 5.0
4.3 out of 5 (445 reviews)

Located in Key Colony Beach, this beachfront hotel is next to a golf course and within 3 mi (5 km) of Captain Hooks Marina an …

$139
Seascape Motel & Marina

Seascape Motel & Marina

1275 76th Oceanside, Marathon 33050

2.5 out of 5.0
4.5 out of 5 (108 reviews)

Nestled on the beach, this Marathon motel is 1.2 mi (2 km) from Conch Air and 1.4 mi (2.3 km) from Sombrero Beach. Island …

$136
Parmer's Resort

Parmer's Resort

565 Barry Avenue, Little Torch Key 33042

2.5 out of 5.0
4 out of 5 (880 reviews)

Situated on the waterfront, this motel is 8.7 mi (13.9 km) from Bahia Honda State Park and Beach and within 20 mi (32 km) o …

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Kingsail Resort

Kingsail Resort

7050 Overseas Highway, Marathon 33050

2.0 out of 5.0
3.4 out of 5 (1,547 reviews)

Located in the heart of Marathon, this motel is within 1 mi (2 km) of Crane Point Museum and Nature Center and Sombrero Beach …

$89
Lime Tree Bay Resort

Lime Tree Bay Resort

68500 Overseas Hwy, Long Key 33001

3.5 out of 5.0
4.1 out of 5 (388 reviews)

This waterfront resort sits on 1/4 mile of tropical waterfront in the heart of the Florida Keys. Close to Long Key State Park …

$109
Looe Key Reef Resort

Looe Key Reef Resort

27340 Overseas Highway, Ramrod Key 33042

2.5 out of 5.0
3.3 out of 5 (368 reviews)

Situated on the waterfront, this hotel is 9.4 mi (15.1 km) from Bahia Honda State Park and Beach and within 25 mi (40 km) o …

$99
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West 33040

4.0 out of 5.0
4.5 out of 5 (2,903 reviews)

This Key West historical district hotel is 2 blocks from Southernmost Point. Ernest Hemingway Home and Museum, and Key West …

$199

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Visiting the Florida Keys is akin to stepping into a whole new world full of live music and cheap drinks. Your cellphone will still work and you don't need a passport, but it's hard to remember that you're still in the good old USA. Year-round perfect temperatures set the scene for swimming, splashing, and displaying your best outfits on the world-famous Duval Street. Whether you want to embrace the laid-back atmosphere by napping on the beach or spending the day visiting historical landmarks like Truman's Winter White House, take plenty of breaks in between for refreshments like a local beer and a slice of Key Lime Pie or two. Whether you're looking for a romantic place to get away from it all or a wild time on Duval, you can find hotels in Florida Keys that let you soak up the fun of the Keys.

All that relaxing in the sun can really take it out of a person! Whether you're heading to bed at midnight or sunrise, you'll want one of the best Florida Keys hotels to do so. Expedia can offer cheap deals on everything from five-star luxury resorts to family-friendly beach spots. If you'd rather be steps from the nightlife action, we've got that covered, too. For a quick weekend getaway to escape the winter blues or an epic two-week family vacation, we have got the accommodation you need to make the most of your stay. Pocket all the cash you save through our hotel discounts and splurge on a sunset sail from Islamadora, a pub crawl in Key West, or a chance to ogle the costumes at the annual Fantasy Fest. Let Expedia get you the best deals for a trip to the Florida Keys you'll remember forever.