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Top 10 Hotels in Florida Keys

See all 257 Hotels in Florida Keys
Tranquility Bay Beachfront Hotel and Resort
Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon 33050

4.0 out of 5.0
4.5 out of 5 (899 reviews)

Located on a private beach in Marathon, Tranquility Bay Beachfront Hotel and Resort is a 5-minute walk from the turtle …

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Parmer's Resort
Parmer's Resort

565 Barry Avenue, Little Torch Key 33042

2.5 out of 5.0
4 out of 5 (783 reviews)

Situated on the waterfront, this motel is within 6 mi (10 km) of Key West Visitors Center, Bahia Honda State Park, and Big …

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Captain Pips Marina & Hideaway
Captain Pips Marina & Hideaway

1410 Overseas Hwy, Marathon 33050-2117

3.0 out of 5.0
4.2 out of 5 (365 reviews)

Situated on the waterfront, this hotel is 0.6 mi (0.9 km) from The Turtle Hospital and 2.3 mi (3.6 km) from Sombrero Beach. …

$159
Skipjack Resort & Marina
Skipjack Resort & Marina

19 Sombrero Blvd, Marathon 33050

2.5 out of 5.0
4.1 out of 5 (16 reviews)

The Skipjack Resort & Marina is located in Marathon in the middle of the Florida Keys, 50 miles from both Key Largo and Key …

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Old Wooden Bridge Marina
Old Wooden Bridge Marina

1791 Bogie Drive, Big Pine Key 33043

2.5 out of 5.0
3.5 out of 5 (2 reviews)

Situated near the beach, this cottage is within 3 mi (5 km) of Blue Hole, Bahia Honda State Park, and Big Pine Flea Market. …

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Margaritaville Key West Resort & Marina
Margaritaville Key West Resort & Marina

245 Front Street, Key West 33040

4.0 out of 5.0
3.8 out of 5 (11 reviews)

Situated in Key West, this hotel is steps from Key West Museum of Art and History and Audubon House and Tropical Gardens. …

$429
Blackfin Resort and Marina
Blackfin Resort and Marina

4650 Overseas Hwy., Marathon 33050

2.0 out of 5.0
3.7 out of 5 (468 reviews)

Located in the heart of Marathon, this hotel is within a 10-minute walk of Marathon Garden Club and Sombrero Beach. Crane …

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Glunz Ocean Beach Hotel & Resort
Glunz Ocean Beach Hotel & Resort

351 East Ocean Drive, Key Colony Beach 33051

3.0 out of 5.0
4.3 out of 5 (428 reviews)

Located in Key Colony Beach, this beachfront hotel is next to a golf course and within a 5-minute walk of Molasses Reef and …

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Hawks Cay Resort
Hawks Cay Resort

61 Hawks Cay Blvd, Duck Key 33050

4.0 out of 5.0
4.2 out of 5 (2,008 reviews)

This Florida Keys resort is on Duck Key, surrounded by the Atlantic Ocean and the Gulf of Mexico. Key Largo is 46 miles north …

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Lime Tree Bay Resort
Lime Tree Bay Resort

68500 Overseas Hwy, Long Key 33001

3.5 out of 5.0
4.2 out of 5 (198 reviews)

This waterfront resort sits on 1/4 mile of tropical waterfront in the heart of the Florida Keys. Close to Long Key State Park …

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Where to stay in Florida Keys

Florida Keys Hotel Guide

Visiting the Florida Keys is akin to stepping into a whole new world full of live music and cheap drinks. Your cellphone will still work and you don't need a passport, but it's hard to remember that you're still in the good old USA. Year-round perfect temperatures set the scene for swimming, splashing, and displaying your best outfits on the world-famous Duval Street. Whether you want to embrace the laid-back atmosphere by napping on the beach or spending the day visiting historical landmarks like Truman's Winter White House, take plenty of breaks in between for refreshments like a local beer and a slice of Key Lime Pie or two. Whether you're looking for a romantic place to get away from it all or a wild time on Duval, you can find hotels in Florida Keys that let you soak up the fun of the Keys.

All that relaxing in the sun can really take it out of a person! Whether you're heading to bed at midnight or sunrise, you'll want one of the best Florida Keys hotels to do so. Expedia can offer cheap deals on everything from five-star luxury resorts to family-friendly beach spots. If you'd rather be steps from the nightlife action, we've got that covered, too. For a quick weekend getaway to escape the winter blues or an epic two-week family vacation, we have got the accommodation you need to make the most of your stay. Pocket all the cash you save through our hotel discounts and splurge on a sunset sail from Islamadora, a pub crawl in Key West, or a chance to ogle the costumes at the annual Fantasy Fest. Let Expedia get you the best deals for a trip to the Florida Keys you'll remember forever.