Top 10 Hotels in Florida Keys

See all 178 Hotels in Florida Keys
Bayside Inn Key Largo
Bayside Inn Key Largo

99490 Overseas Hwy, Key Largo 33037

2.5 out of 5.0
3.1 out of 5 (1,685 reviews)

This beachfront Florida Bay hotel is in the center of Key Largo, within walking distance to numerous restaurants and coffee …

$67
Holiday Inn Express Hotel & Suites Marathon
Holiday Inn Express Hotel & Suites Marathon

13201 Overseas Hwy, Marathon 33050

2.5 out of 5.0
4.3 out of 5 (1,336 reviews)

Situated on the waterfront, this hotel is within 2 mi (3 km) of Captain Hooks Marina and Dive Center, Conch Air, and Island …

$129
Ocean Key Resort - A Noble House Resort
Ocean Key Resort - A Noble House Resort

Zero Duval St., Key West 33040

4.0 out of 5.0
4.6 out of 5 (1,467 reviews)

Overlooking the Gulf of Mexico from the western edge of Duval Street, this Key West resort adjacent to Mallory Square …

$242
Lighthouse Court Hotel - Key West
Lighthouse Court Hotel - Key West

902 Whitehead St, Key West 33040

3.5 out of 5.0
4.1 out of 5 (797 reviews)

This small hotel is located across the street from the Hemingway Home and Museum and next door to the Key West Lighthouse & …

$169
Best Western Key Ambassador Resort Inn
Best Western Key Ambassador Resort Inn

3755 S Roosevelt Blvd, Key West 33040

2.5 out of 5.0
4 out of 5 (1,554 reviews)

Located on the Atlantic side of Island and just minutes from the Key West Art Society and Historical Downtown. Nearby points …

$136
Key West Inn Key Largo
Key West Inn Key Largo

201 Ocean Drive, Key Largo 33037

2.5 out of 5.0
3.7 out of 5 (792 reviews)

Situated in Key Largo, this hotel is 1.2 mi (2 km) from Dolphins Plus and within 3 mi (5 km) of Dolphins Plus Bayside and …

$72
Albury Court Hotel - Key West
Albury Court Hotel - Key West

1030 Eaton St, Key West 33040

3.0 out of 5.0
4 out of 5 (1,340 reviews)

Albury Court is a 15-minute walk from the bars and restaurants of Duval Street, the island's popular nightlife destination …

$139
Sombrero Resort & Marina
Sombrero Resort & Marina

19 Sombrero Blvd, Marathon 33050

2.0 out of 5.0
3.1 out of 5 (1,085 reviews)

The Sombrero Resort & Marina is located in Marathon in the middle of the Florida Keys, 50 miles from both Key Largo and Key …

$93
Casa Marina Resort - A Waldorf Astoria Resort
Casa Marina Resort - A Waldorf Astoria Resort

1500 Reynolds Street, Key West 33040

4.0 out of 5.0
4.2 out of 5 (2,137 reviews)

Looking out over the Straits of Florida towards Cuba, this upscale resort places guests a 3-minute drive from downtown Key …

$299
Dove Creek Lodge, an Ascend Hotel Collection Member
Dove Creek Lodge, an Ascend Hotel Collection Member

147 Seaside Ave, Key Largo 33037

3.0 out of 5.0
4.5 out of 5 (168 reviews)

Situated on the waterfront, this hotel is within 1 mi (2 km) of Florida Keys Wild Bird Rehabilitation Center and Florida Keys …

$159

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Where to stay in Florida Keys

Florida Keys Hotel Guide

Visiting the Florida Keys is akin to stepping into a whole new world full of live music and cheap drinks. Your cellphone will still work and you don't need a passport, but it's hard to remember that you're still in the good old USA. Year-round perfect temperatures set the scene for swimming, splashing, and displaying your best outfits on the world-famous Duval Street. Whether you want to embrace the laid-back atmosphere by napping on the beach or spending the day visiting historical landmarks like Truman's Winter White House, take plenty of breaks in between for refreshments like a local beer and a slice of Key Lime Pie or two. Whether you're looking for a romantic place to get away from it all or a wild time on Duval, you can find hotels in Florida Keys that let you soak up the fun of the Keys.

All that relaxing in the sun can really take it out of a person! Whether you're heading to bed at midnight or sunrise, you'll want one of the best Florida Keys hotels to do so. Expedia can offer cheap deals on everything from five-star luxury resorts to family-friendly beach spots. If you'd rather be steps from the nightlife action, we've got that covered, too. For a quick weekend getaway to escape the winter blues or an epic two-week family vacation, we have got the accommodation you need to make the most of your stay. Pocket all the cash you save through our hotel discounts and splurge on a sunset sail from Islamadora, a pub crawl in Key West, or a chance to ogle the costumes at the annual Fantasy Fest. Let Expedia get you the best deals for a trip to the Florida Keys you'll remember forever.