Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Fort Myers Beach Business Hotels

See all 327 Hotels in Fort Myers Beach
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

11281 Summerlin Square Dr, Fort Myers Beach
2.5 out of 5.0
4.3 out of 5 (299 reviews)
Great breakfast. Love the waffles. The room was comfortable and quiet. The checking easy and friendly. The grounds was clean. Easy to find.
  Sep 23, 2017

$88

$88
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

1400 Estero Blvd, Fort Myers Beach
3.0 out of 5.0
3.1 out of 5 (968 reviews)
great place to goI had a great time, thought there might be problems because of the hurricane, but what they did was take care of it and go on just a ausom hotel in my book
  Sep 23, 2017

$134

$134
Gulfview Manor Resort

Gulfview Manor Resort

6530 Estero Blvd, Fort Myers Beach
3.0 out of 5.0
4.6 out of 5 (318 reviews)
Beautiful hotel, on a quiet clean beach. Easy check in , nice people very clean. On beach every morning, best beach I've ever even on.
  Jun 26, 2017
DiamondHead Beach Resort

DiamondHead Beach Resort

2000 Estero Blvd, Fort Myers Beach
3.5 out of 5.0
4.5 out of 5 (932 reviews)
Short but sweetArrived Tuesday the 5th to start our week. Unfortunately, hurricane Irma had other plans. The room was great and bed was comfortable. Hotel very clean. Great staff and outdoor restaurant. They were understanding when we cancelled the rest of our stay the next day and started driving North to avoid ...
  Sep 12, 2017

$152

$152
The Neptune Resort

The Neptune Resort

2310 Estero Blvd, Fort Myers Beach
3.0 out of 5.0
4.4 out of 5 (647 reviews)
Hotel right on the beach. Great views of the GulfStayed at the Neptune for a week. The hotel was very nice, the room was large enough room for five of us. The pool area was very nice with two saltwater pools and plenty of loungers and tables. The beach was also very clean and we were right on the beach. The staff was very nice, but tried to upsell ...
  Aug 25, 2017

$140

$140
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

1051 5th St, Fort Myers Beach
3.0 out of 5.0
3.7 out of 5 (710 reviews)
Nice hotela good hotel for a good holiday this very close to the beach the price very good and the workers very nice
  Sep 25, 2017

$82

$82
GullWing Beach Resort

GullWing Beach Resort

6620 Estero Blvd, Fort Myers Beach
3.5 out of 5.0
4.7 out of 5 (308 reviews)
This hotel was specious and had everything we needed. I love the kitchen and shower and the view of the beach
  Sep 26, 2017

$169

$169
Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

275 Estero Blvd, Fort Myers Beach
4.0 out of 5.0
4.5 out of 5 (756 reviews)
On the beach. Food is ok. Staff is awesome.This was our 3rd stay here. Not really fair to say too much as hurricane Irma just blasted through here. The last 2 times were perfect, ill leave it at that.
  Sep 24, 2017

$199

$199
Lovers Key Resort

Lovers Key Resort

8771 Estero Blvd, Fort Myers Beach
3.0 out of 5.0
4.5 out of 5 (187 reviews)
Furniture issuesThe furniture is very old. The Sofa bed sleepers mattress was "very bad" . Impossible to rest. I forgot to elevate this to a formal complaint. Therefore,
  Sep 5, 2017

$149

$149
Beach Club I

Beach Club I

326 Estero Blvd.,, Fort Myers Beach
3.0 out of 5.0
Bel-air Beach Club

Bel-air Beach Club

780 Estero Blvd.,, Fort Myers Beach
3.5 out of 5.0
Hideaway Village

Hideaway Village

5607 Estero Blvd, Fort Myers Beach
2.0 out of 5.0
4.2 out of 5 (115 reviews)
Wonderful room, great staff, free umbrellas, wagonWonderful room, great staff, free chairs, wagon, umbrellas to the beach. Very clean room, great patio and deck and pool. Easy to find and park at. There is no daily housekeeping, which we prefer, but just a heads up. But they will get you anything you need, night or day. Quaint quiet place with views ...
  Sep 8, 2017

$95

$95
Manatee Bay Inn

Manatee Bay Inn

932 Third St, Fort Myers Beach
2.5 out of 5.0
4.6 out of 5 (15 reviews)
Great little hidden gem :) We came down from Ohio for a quick weekend stay and loved this little place! The owners were very friendly and attentive and our room was perfect- nothing super fancy but was extremely clean and had everything we needed. Wished we could have stayed for a couple more days!
  Jun 29, 2015

$135

$135
Pointe Estero Beach Resort

Pointe Estero Beach Resort

6640 Estero Blvd, Fort Myers Beach
3.5 out of 5.0
4.6 out of 5 (359 reviews)
nice hotel and location. hotel staff was okay. pleasant, clean room, nice location, not cheap rather expensive,
  Sep 5, 2017

$189

$189
Sandcastle Beach Club

Sandcastle Beach Club

905 Estero Blvd.,, Fort Myers Beach
3.5 out of 5.0
Silver Sands Villas

Silver Sands Villas

1207 Estero Blvd., Fort Myers Beach
3.0 out of 5.0
5.0 out of 5 (1 reviews)
Super Cute & Great LocationThis property is nothing but cute! And the staff is awesome. They are so accommodating and make you feel right at home. You can not beat this location. Within walking or trolley to everywhere and the beach is literally across the street! I came to spend the weekend with my daughter, will be ...
  Nov 22, 2016
Tip Top Isles Waterfront Resort & Marina

Tip Top Isles Waterfront Resort & Marina

17863 San Carlos Blvd, Fort Myers Beach
2.0 out of 5.0
3.3 out of 5 (36 reviews)
Nice hotelNice place. New owners still getting their bearings. They were very friendly and helpful. Room was good. Nice 2 bedroom suite. Not large but good. Negatives: no glasses only plastic, not enough kitchen linens, floors seemed clean and place smelled clean but my bare feet got filthy!!! Needed 4 chairs ...
  Feb 25, 2017

$75

$75
Wyndham Garden Fort Myers Beach

Wyndham Garden Fort Myers Beach

6890 Estero Blvd, Fort Myers Beach
3.0 out of 5.0
3.9 out of 5 (337 reviews)
This hotel was very nice . Right on the beach. Nice staff there. Clean room. Bed was comfortable. Bathroom was nice size. We had a refrigerator and microwave which was a plus. Beach is within walking distance. Pool was having repairs done so we did not use it . They have a restaurant and a beach bar. Both were good. Nice place. I would stay there ...
  Sep 21, 2017

$97

$97
Tahitian Inn Motel

Tahitian Inn Motel

17761 San Carlos Blvd, Fort Myers Beach
2.0 out of 5.0
2.8 out of 5 (43 reviews)
Great hotelThe staff is very nice, there is a fridge, microwave and coffee maker which I appreciated and it's close to the beach! Would definitely recommend and stay here again!
  Aug 2, 2017

$57

$57
Dolphin Inn Resort

Dolphin Inn Resort

6555 Estero Blvd., Fort Myers Beach
2.0 out of 5.0
4.0 out of 5 (317 reviews)
Very nice place,loved the bay side docks Pool very well keeper They do need new shower heads tho Would book again,hope it's still after this Hurricane
  Sep 10, 2017

$69

$69
Map

Recently booked Business Hotels in Fort Myers Beach

Lani Kai Beachfront Resort
2.5 out of 5.0
Last booking: 3 minutes ago
Sandpiper Gulf Resort
3.0 out of 5.0
Last booking: 21 minutes ago
Sun Deck Inn and Suites
2.0 out of 5.0
Last booking: 1 hour ago
Flamingo Inn
2.0 out of 5.0
Last booking: 3 hours ago
Lovers Key Resort
3.0 out of 5.0
Last booking: 4 hours ago
Diamondhead Beach Resort and Spa
3.5 out of 5.0
Last booking: 9 hours ago
Wyndham Garden Fort Myers Beach
3.0 out of 5.0
Last booking: 15 hours ago
Carousel Inn on the Beach
2.0 out of 5.0
Last booking: 16 hours ago
Tahitian Inn Motel
2.0 out of 5.0
Last booking: 17 hours ago

Pocket Guide: Business Hotels in Fort Myers Beach

Search for hotels in Fort Myers Beach on Expedia. You can easily find your hotels in Fort Myers Beach using one of the methods below:

  • View our selection of featured hotels in Fort Myers Beach
  • Use the map to find hotels in the Fort Myers Beach neighborhood you prefer
  • Use the filters to see hotels in a specific area of Fort Myers Beach, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Fort Myers Beach
  • Enter your travel dates to view the best deals on hotels in Fort Myers Beach - while they last